EKS-SUS-00059

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00059

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	370.4	6.8E-111	89	373	285

Status

Unreviewed

Ensembl Protein

ENSSSCP00000016234

UniProt Accession

F1S320;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK14

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000015307	ENSSSCP00000016234	ENSSSCT00000016680

Organism

Sus scrofa

Functional Description

Protein Length

423

Protein Sequence
(FASTA)

MSTRNCPGMD SMIKPLDTIP EDKKVRVQRT QSTFDPFEKP ANQVKRVHSE NNACINFKTS 60

SAGKESPKVR RHSSPSSPTS PKFGKADSYE KLEKLGEGSY ATVYKGKSKV NGKLVALKVI 120

RLQEEEGTPF TAIREASLLK GLKHANIVLL HDIIHTKETL TLVFEYVHTD LCQYMDKHPG 180

GLHPENVKLF LFQLLRGLSY IHQRYILHRD LKPQNLLISD TGELKLADFG LARAKSVPSH 240

TYSNEVVTLW YRPPDVLLGS TEYSTCLDMW GVGCIFVEMI QGVAAFPGMK DIQDQLERIF 300

LVLGTPNEDT WPGVHSLPHF KPERFTLYSS KNLRQAWNKL SYVNHAEDLA SKLLQCSPKN 360

RLSAQAALSH EYFSDLPPRL WELTDMSSIF TVPNVRLQPE AGESTRAFGK NNSYGKSLSN 420

SKH 423

Nucleotide Sequence
(FASTA)

ATGTCTACAC GGAACTGCCC GGGAATGGAC TCAATGATCA AACCCTTGGA CACAATTCCT 60

GAGGATAAGA AAGTCAGGGT TCAGAGGACC CAGAGCACTT TTGACCCATT TGAGAAACCA 120

GCTAATCAAG TCAAGAGGGT GCATTCCGAG AACAATGCTT GCATTAACTT TAAGACCTCC 180

TCTGCTGGCA AAGAGTCTCC TAAAGTTCGG CGGCACTCCA GCCCCAGCTC GCCAACAAGT 240

CCCAAATTTG GAAAAGCTGA CTCATATGAA AAACTGGAAA AACTAGGGGA AGGATCTTAT 300

GCTACAGTAT ACAAAGGGAA AAGCAAGGTA AATGGGAAGT TGGTAGCCCT GAAGGTGATC 360

AGGCTGCAAG AAGAAGAAGG TACCCCTTTT ACAGCTATCA GGGAAGCTTC TCTGTTAAAA 420

GGACTGAAAC ATGCTAACAT AGTGCTGCTT CATGACATCA TCCACACAAA GGAGACGCTG 480

ACCCTTGTGT TTGAATATGT GCACACTGAT TTATGTCAGT ACATGGACAA GCATCCTGGG 540

GGGCTGCACC CAGAGAATGT GAAGTTGTTT TTATTTCAGT TGCTGCGAGG GCTGTCTTAC 600

ATCCACCAGC GTTATATTTT GCACAGAGAC CTGAAACCAC AGAACCTTCT GATCAGTGAC 660

ACGGGGGAGT TAAAGCTGGC AGATTTCGGT CTTGCAAGAG CAAAATCTGT CCCTAGCCAC 720

ACATACTCCA ATGAAGTGGT GACTTTGTGG TACAGACCTC CAGATGTCCT CCTGGGCTCA 780

ACAGAATATT CTACCTGCCT TGACATGTGG GGAGTTGGCT GTATCTTTGT TGAAATGATC 840

CAAGGAGTCG CTGCTTTTCC AGGAATGAAA GACATTCAGG ATCAACTTGA ACGAATATTT 900

CTGGTTCTTG GGACGCCCAA TGAGGACACA TGGCCTGGAG TTCATTCTTT ACCACATTTT 960

AAGCCAGAAC GCTTTACCCT GTACAGCTCT AAAAACCTTA GACAAGCATG GAATAAGCTC 1020

AGCTATGTGA ATCATGCAGA GGATCTGGCC TCCAAGCTCC TACAGTGTTC CCCAAAGAAC 1080

AGACTATCAG CCCAGGCTGC CTTGAGCCAC GAGTATTTTA GTGACCTGCC CCCACGGCTA 1140

TGGGAACTGA CTGATATGTC TTCTATTTTT ACCGTCCCAA ATGTAAGATT GCAACCAGAA 1200

GCTGGAGAAA GCACGCGGGC CTTTGGGAAA AACAATAGTT ATGGCAAAAG TCTGTCAAAC 1260

AGCAAGCACT GA 1272

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yeklek+geG+y++vyk+k+k +g++vAlK irl++e eg p+ta+rE sllk lkh+ni

Q: 89    YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHANI  147

         99********************************998.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l+Lvfe++++dL ++++k++  +l++e+vk +l+qll+gl+y+H++

Q: 148   VLLHDIIH-TKETLTLVFEYVHTDLCQYMDKHPG-GLHPENVKLFLFQLLRGLSYIHQRY  205

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLis++g+lklaDfGlara s+p++ty++evvTlwYr+P++Llg++eYst

Q: 206   ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYST  265

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

          +D+W+vgci++e+++  + f+g ++ +dqlerif +lgtp+e++wp+v++lp++k ++f

Q: 266   CLDMWGVGCIFVEMIQGVAAFPGMKDiQDQLERIFLVLGTPNEDTWPGVHSLPHFKpERF  325

         ************************99679***************************9999

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

         + +++k+l++ ++kl+  ++a dl +kll+++pk+R+sa++al+h+yf

Q: 326   TLYSSKNLRQAWNKLSyvNHAEDLASKLLQCSPKNRLSAQAALSHEYF  373

         99**********99997678***************************9

Domain Sequence
(FASTA)

YEKLEKLGEG SYATVYKGKS KVNGKLVALK VIRLQEEEGT PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTLVFEYVH TDLCQYMDKH PGGLHPENVK LFLFQLLRGL SYIHQRYILH 120

RDLKPQNLLI SDTGELKLAD FGLARAKSVP SHTYSNEVVT LWYRPPDVLL GSTEYSTCLD 180

MWGVGCIFVE MIQGVAAFPG MKDIQDQLER IFLVLGTPNE DTWPGVHSLP HFKPERFTLY 240

SSKNLRQAWN KLSYVNHAED LASKLLQCSP KNRLSAQAAL SHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013