EKS-SUS-00365

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00365

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	438.4	1.0E-131	35	293	259

Status

Unreviewed

Ensembl Protein

ENSSSCP00000017021

UniProt Accession

F1SN17;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17B

Gene Synonyms/Alias

STK17B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000016067	ENSSSCP00000017021	ENSSSCT00000017493

Organism

Sus scrofa

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSRRRFDCRS ISGLLTTTPQ TPMKMDNFNN FYTLTSKELG RGKFAVVRQC ISKSTGQEYA 60

AKFLKKRRRG QDCRAEILHE IAVLELAKSC PHVINLHEVY ENASEIILVL EYAAGGEIFN 120

LCLPELAEMV SENDIIRLIK QILEGVYYLH QNNIVHLDLK PQNILLSSIY PLGDIKIVDF 180

GMSRKIGNAC ELREIMGTPE YLAPEILNYD PITTATDMWN VGVIAYMLLT HTSPFVGEDN 240

QETYLNISQV NVDYSEETFS SVSQLATDFI QRLLVKNPEK RPTAEICLSH SWLQQWDFGN 300

LFHPEETSSS SQSQDHTIRS SEDKTSKPSC NGTCSDREDK ENIPEDSSMV SKRFRFDDSL 360

PNPHELVSDL LC 372

Nucleotide Sequence
(FASTA)

ATGTCAAGGA GAAGATTTGA TTGCCGAAGT ATTTCAGGCT TGCTAACTAC AACTCCTCAA 60

ACTCCAATGA AAATGGATAA CTTTAATAAT TTTTATACAC TTACATCTAA AGAGCTAGGA 120

AGAGGAAAAT TTGCTGTGGT TAGGCAATGT ATATCCAAAT CTACTGGCCA AGAATATGCT 180

GCAAAATTTC TGAAAAAGAG AAGAAGAGGA CAGGATTGTC GAGCAGAGAT TCTACATGAG 240

ATTGCAGTAC TTGAATTGGC GAAGTCCTGT CCCCACGTGA TTAATCTTCA TGAAGTCTAT 300

GAAAATGCAA GTGAAATCAT TTTGGTATTG GAATATGCTG CAGGTGGAGA AATCTTCAAC 360

TTGTGTTTAC CTGAGTTGGC TGAAATGGTC TCTGAAAATG ACATTATCAG ACTCATTAAA 420

CAAATACTTG AAGGAGTTTA TTATCTACAT CAAAATAACA TTGTACACCT TGATTTAAAG 480

CCACAGAATA TATTATTAAG CAGCATATAC CCTCTTGGGG ACATAAAAAT TGTAGATTTT 540

GGAATGTCTC GAAAAATAGG GAATGCATGT GAACTTCGGG AAATCATGGG AACACCAGAA 600

TACTTGGCAC CTGAAATCCT GAACTATGAT CCTATTACCA CAGCAACAGA TATGTGGAAT 660

GTTGGTGTAA TAGCATATAT GTTGTTAACT CATACATCAC CATTTGTGGG AGAAGATAAT 720

CAAGAAACAT ACCTCAACAT TTCTCAAGTT AATGTAGATT ATTCAGAAGA AACATTTTCA 780

TCAGTTTCAC AGCTGGCCAC AGACTTCATC CAGAGGCTTT TAGTAAAAAA CCCAGAGAAA 840

AGACCGACAG CCGAAATCTG CCTTTCTCAT TCTTGGCTAC AGCAGTGGGA CTTTGGAAAC 900

TTGTTTCACC CTGAAGAAAC TTCCAGTTCC TCTCAAAGTC AGGATCATAC AATAAGGTCT 960

TCTGAAGACA AGACTTCTAA ACCCTCCTGT AATGGAACCT GCAGTGACCG AGAAGACAAA 1020

GAGAACATCC CGGAGGATAG CAGCATGGTG TCCAAAAGAT TTCGCTTTGA TGACTCATTG 1080

CCCAATCCCC ATGAACTTGT TTCAGATTTG CTCTGTTAG 1119

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

         t+kelg+Gkfavvr+c++kstG+eyaakflkkrr    r++++r+ei +e+avl++++s+

Q: 35    TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRR----RGQDCRAEILHEIAVLELAKSC  90

         789*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         p+vinlhevyen+s++il+le++aGGe+f+  l + +e++se+++++l+kqilegv+ylh

Q: 91    PHVINLHEVYENASEIILVLEYAAGGEIFNlcLPELAEMVSENDIIRLIKQILEGVYYLH  150

         ******************************877899************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         +++ivhldlkP+nill++ + p gdik++dfG+srki +++el+ei+GtPe++aPei+ny

Q: 151   QNNIVHLDLKPQNILLSSIY-PLGDIKIVDFGMSRKIGNACELREIMGTPEYLAPEILNY  209

         ********************.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p++++tdmw++Gvi+y+ll+++sPf+G+++qet+lnis+vn+d+see+fssvs+la+df

Q: 210   DPITTATDMWNVGVIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDF  269

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         i+rllvk+pekr t+e cl+hswl

Q: 270   IQRLLVKNPEKRPTAEICLSHSWL  293

         ***********************7

Domain Sequence
(FASTA)

TSKELGRGKF AVVRQCISKS TGQEYAAKFL KKRRRGQDCR AEILHEIAVL ELAKSCPHVI 60

NLHEVYENAS EIILVLEYAA GGEIFNLCLP ELAEMVSEND IIRLIKQILE GVYYLHQNNI 120

VHLDLKPQNI LLSSIYPLGD IKIVDFGMSR KIGNACELRE IMGTPEYLAP EILNYDPITT 180

ATDMWNVGVI AYMLLTHTSP FVGEDNQETY LNISQVNVDY SEETFSSVSQ LATDFIQRLL 240

VKNPEKRPTA EICLSHSWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis

KEGG

ssc:100153033

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013