EKS-SUS-00212

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00212

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	317.5	7.2E-95	3	237	235

Status

Unreviewed

Ensembl Protein

ENSSSCP00000017863

UniProt Accession

D0G7E1;

Protein Name

Protein Synonyms/Alias

Protein kinase, AMP-activated, alpha 1 catalytic subunit;

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000016858	ENSSSCP00000017863	ENSSSCT00000018359

Organism

Sus scrofa

Functional Description

Protein Length

517

Protein Sequence
(FASTA)

VGKHELTGHK VAVKILNRQK IRSLDVVGKI RREIQNLKLF RHPHIIKLYQ VISTPSDIFM 60

VMEYVSGGEL FDYICKNGRL DEKESRRLFQ QILSGVDYCH RHMVVHRDLK PENVLLDAHM 120

NAKIADFGLS NMMSDGEFLR TSCGSPNYAA PEVISGRLYA GPEVDIWSSG VILYALLCGT 180

LPFDDDHVPT LFKKICDGIF YTPQYLNPSV ISLLKHMLQV DPMKRATIKD IREHEWFKQD 240

LPKYLFPEDP SYSSTMIDDE ALKEVCEKFE CSEEEVLSCL YNRNHQDPLA VAYHLIIDNR 300

RIMNEAKDFY LATSPPDSFL DDHHLTRPHP ERVPFLVAET PRARHTLDEL NPQKSKHQGV 360

RKAKWHLGIR SQSRPNDIMA EVCRAIKQLD YEWKVVNPYY LRVRRKNPVT STYSKMSLQL 420

YQVDSRTYLL DFRSIDDEIT EAKSGTATPQ RSGSVSNYRA CQRNDSDAEA QGKSSEASLT 480

SSVTSLDSSP VDLTPRPGSH TIEFFEMCAN LIKILAQ 517

Nucleotide Sequence
(FASTA)

GTTGGCAAAC ATGAATTGAC TGGTCATAAA GTTGCTGTGA AGATACTCAA TCGACAGAAG 60

ATTCGAAGCC TTGATGTAGT AGGAAAAATC CGCAGAGAAA TTCAGAACCT CAAGCTTTTC 120

AGGCATCCTC ATATAATTAA ATTGTACCAG GTCATCAGTA CACCATCTGA TATTTTCATG 180

GTGATGGAAT ATGTTTCAGG AGGCGAGCTA TTTGATTATA TCTGTAAAAA TGGAAGGCTG 240

GATGAAAAAG AAAGTCGACG TCTCTTCCAA CAAATCCTTT CTGGTGTGGA TTATTGTCAC 300

AGGCATATGG TGGTCCACAG AGATTTGAAA CCTGAAAATG TCCTGCTTGA TGCACACATG 360

AATGCAAAAA TAGCTGACTT CGGTCTTTCA AACATGATGT CAGATGGTGA ATTTTTAAGA 420

ACGAGTTGTG GCTCACCCAA CTATGCTGCA CCAGAAGTAA TTTCAGGAAG GTTGTATGCT 480

GGTCCAGAGG TAGATATATG GAGCAGTGGG GTTATTCTCT ATGCTTTATT ATGTGGAACA 540

CTTCCATTTG ATGATGATCA TGTGCCAACT CTTTTTAAGA AGATTTGTGA TGGGATCTTT 600

TATACCCCTC AGTATTTAAA TCCTTCTGTG ATTAGCCTTT TGAAACATAT GCTACAGGTG 660

GATCCCATGA AGAGAGCCAC AATCAAAGAT ATCAGGGAAC ATGAATGGTT TAAACAGGAC 720

CTTCCAAAAT ATCTCTTTCC TGAGGATCCA TCGTATAGTT CAACCATGAT TGATGATGAA 780

GCCTTAAAAG AAGTATGTGA AAAATTTGAA TGCTCAGAAG AGGAGGTTCT CAGCTGCCTT 840

TATAACAGAA ATCACCAGGA CCCTTTGGCA GTTGCCTACC ACCTTATAAT AGATAACAGG 900

AGAATAATGA ATGAGGCCAA AGATTTTTAC TTGGCAACAA GCCCACCTGA TTCTTTTCTT 960

GATGATCACC ATTTGACTCG GCCCCATCCT GAAAGAGTAC CGTTTTTGGT TGCTGAAACT 1020

CCAAGGGCAC GCCATACCCT TGATGAATTA AATCCACAAA AATCCAAACA CCAAGGTGTA 1080

AGGAAAGCAA AATGGCATTT GGGAATTAGA AGTCAAAGTC GACCCAATGA TATCATGGCA 1140

GAAGTTTGTA GAGCAATTAA ACAACTGGAT TATGAGTGGA AGGTTGTAAA TCCATATTAT 1200

TTGCGTGTTC GAAGGAAGAA TCCTGTGACA AGTACATACT CCAAAATGAG TCTACAATTA 1260

TACCAAGTGG ATAGTAGGAC GTACTTATTG GATTTCCGTA GTATTGATGA TGAAATTACT 1320

GAAGCCAAAT CAGGGACTGC TACTCCACAG AGATCGGGCT CAGTTAGCAA CTATCGAGCT 1380

TGCCAAAGGA ATGATTCAGA TGCTGAGGCT CAAGGAAAAT CCTCAGAAGC TTCTCTTACC 1440

TCATCTGTAA CCTCACTTGA CTCTTCTCCT GTTGACTTAA CTCCAAGACC TGGAAGTCAC 1500

ACAATAGAAT TTTTTGAGAT GTGTGCAAAT CTAATTAAAA TTCTTGCACA GTAA 1554

Domain Profile

S: 19    khketkekvavKiikkkkl.seeslekikrEieilkklkhpniikllevietkkklylvl  77

         kh++t++kvavKi++++k+ s + + ki+rEi+ lk ++hp+iikl++vi+t +++++v+

Q: 3     KHELTGHKVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVM  62

         7999**************96667788**********************************

S: 78    eyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllldkkeni  137

         ey+sggeLfdyi ++grl+eke+r+lf+q++s+v+Y+h++ +vHrDlKpeN+lld+++n

Q: 63    EYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNA  122

         ************************************************************

S: 138   kiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalvtgklP  197

         kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+vD+Ws Gv+Lyal++g+lP

Q: 123   KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP  182

         ************************************************************

S: 198   fdeenlkellekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         fd++++ +l++ki +g + +p++l+++++sLl+++L+vdp kRati++i++hew+

Q: 183   FDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF  237

         ******************************************************7

Domain Sequence
(FASTA)

KHELTGHKVA VKILNRQKIR SLDVVGKIRR EIQNLKLFRH PHIIKLYQVI STPSDIFMVM 60

EYVSGGELFD YICKNGRLDE KESRRLFQQI LSGVDYCHRH MVVHRDLKPE NVLLDAHMNA 120

KIADFGLSNM MSDGEFLRTS CGSPNYAAPE VISGRLYAGP EVDIWSSGVI LYALLCGTLP 180

FDDDHVPTLF KKICDGIFYT PQYLNPSVIS LLKHMLQVDP MKRATIKDIR EHEWF 235

Keyword

ATP-binding; Kinase; Nucleotide-binding; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ssc:100145903

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013