EKS-SUS-00065

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00065

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	323.5	1.4E-96	103	337	235

Status

Unreviewed

Ensembl Protein

ENSSSCP00000019184

UniProt Accession

I3L585;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000022296	ENSSSCP00000019184	ENSSSCT00000023339

Organism

Sus scrofa

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MGQELCAKTL QPGCSCHRCW EGGDAHSGQR SAPVTVEAAM ELADLKEASC SMTSFHPRGP 60

QSVHARKFKN KRPRSNSDSF QEEHLRQSFQ WTKSLPFGAA SSYLNLEKLG EGSYATVYKG 120

ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 180

VHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 240

ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 300

PGVSNILEQL EKIWEVVGVP TEDTWPGVSK LPNYNPVWIP HPFPNT 346

Nucleotide Sequence
(FASTA)

ATGGGTCAAG AGCTGTGTGC AAAGACTCTC CAGCCTGGAT GCAGCTGCCA TCGCTGTTGG 60

GAGGGAGGCG ATGCACACAG CGGTCAGAGG AGTGCGCCTG TGACCGTGGA GGCTGCGATG 120

GAGCTAGCAG ACCTAAAAGA AGCATCATGT TCCATGACTT CATTTCACCC CAGGGGACCT 180

CAGTCTGTCC ATGCCCGGAA GTTCAAGAAT AAAAGGCCAC GGAGTAATAG CGATTCTTTT 240

CAGGAAGAGC ATCTGAGGCA GAGTTTTCAG TGGACGAAGA GCCTTCCCTT TGGGGCAGCC 300

TCATCTTACC TGAACTTGGA GAAGCTGGGT GAAGGCTCTT ATGCTACAGT TTACAAGGGG 360

ATCAGCAGGA TAAATGGACA ACTAGTGGCT TTAAAAGTCA TCAGCATGAA TGCAGAGGAA 420

GGAGTCCCAT TTACAGCCAT CCGGGAAGCT TCTCTCCTGA AGGGTTTGAA ACATGCCAAT 480

ATTGTGCTCT TGCATGACAT AATCCACACC AAAGAGACAC TGACATTCGT TTTTGAATAC 540

GTGCACACGG ACCTGGCCCA GTATATGTCC CAGCACCCAG GAGGGCTTCA TCCTCACAAT 600

GTCAGGCTTT TCATGTTTCA ACTTTTGCGG GGCCTGGCAT ACATCCACCA CCAACACGTT 660

CTTCACAGGG ACCTGAAACC TCAGAATTTA CTCATCAGTC ACCTGGGAGA GCTCAAACTG 720

GCTGATTTTG GTCTTGCTCG GGCCAAATCC ATTCCCAGCC AGACATACTC TTCAGAAGTT 780

GTGACTCTCT GGTACCGCCC TCCTGATGCC CTGCTGGGAG CTACTGAGTA TTCTTCTGAA 840

CTGGACATAT GGGGTGCAGG CTGCATCTTT ATTGAAATGT TCCAGGGTCA ACCGTTGTTT 900

CCTGGGGTTT CCAACATCCT TGAACAGCTG GAGAAGATCT GGGAGGTGGT GGGAGTCCCT 960

ACAGAGGATA CCTGGCCTGG GGTTTCCAAG CTACCTAACT ACAATCCAGT GTGGATTCCA 1020

CATCCATTTC CAAATACC 1038

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geG+y++vyk+ ++ +g++vAlK i ++ e egvp+ta+rE sllk lkh+ni

Q: 103   YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANI  161

         6789******************************998.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l++vfe++++dL++++++++  +l++++v+ +++qll+glay+H+++

Q: 162   VLLHDIIH-TKETLTFVFEYVHTDLAQYMSQHPG-GLHPHNVRLFMFQLLRGLAYIHHQH  219

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLis+ g+lklaDfGlara s p++ty++evvTlwYr+P+ Llga+eYs+

Q: 220   VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS  279

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.k  236

         ++DiW++gci+ e+++ +plf+g s+  +qle+i++++g p+e++wp+vsklp+y+

Q: 280   ELDIWGAGCIFIEMFQGQPLFPGVSNiLEQLEKIWEVVGVPTEDTWPGVSKLPNYNpV  337

         ***********************99967***************************943

Domain Sequence
(FASTA)

YLNLEKLGEG SYATVYKGIS RINGQLVALK VISMNAEEGV PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTFVFEYVH TDLAQYMSQH PGGLHPHNVR LFMFQLLRGL AYIHHQHVLH 120

RDLKPQNLLI SHLGELKLAD FGLARAKSIP SQTYSSEVVT LWYRPPDALL GATEYSSELD 180

IWGAGCIFIE MFQGQPLFPG VSNILEQLEK IWEVVGVPTE DTWPGVSKLP NYNPV 235

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013