EPS-SUS-00023

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SUS-00023

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	168.4	3.1E-49	308	501	194

Status

Unreviewed

Ensembl Protein

ENSSSCP00000027484

UniProt Accession

I3LTN6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1G

Gene Synonyms/Alias

PPM1G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000027135	ENSSSCP00000027484	ENSSSCT00000023870

Organism

Sus scrofa

Functional Description

Protein Length

545

Protein Sequence
(FASTA)

MGAYLSQPNT VKCSGDGVGA SRLPLPYGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD 60

GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA IDAKLTTEEV IKELAQIAGR 120

PTEDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY GQNCHKGAPH SKSGAGTGEE 180

AGSQGLNGEA GPEDPSRETS SEENGPTAKA HTGLSSNSER GTEAGQGGEP GTPTGEAGPS 240

CSSASDKLPR VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE 300

AEEDEEEEEE MMVPGMEGKE EPGSDSGTTA VVALIRGKQL IVANAGDSRC VVSEAGKALD 360

MSYDHKPEDE VELARIKNAG GKVTMDGRVN GGLNLSRAIG DHFYKRNKNL PPEEQMISAL 420

PDIKVLTLTD DHEFMVIACD GIWNVMSSQE VIDFIQSKIS QRDENGELRL LSSIVEELLD 480

QCLAPDTSGD GTGCDNMTCI IICFKPRNTA ELQPESGKRK LEEVLSTEGA EENGNSDNKK 540

KAKRD 545

Nucleotide Sequence
(FASTA)

ATGGGTGCCT ACCTCTCCCA GCCCAACACG GTGAAGTGCT CTGGGGACGG GGTCGGCGCC 60

TCGCGCCTGC CGCTGCCCTA CGGCTTCTCC GCCATGCAAG GCTGGCGCGT CTCCATGGAG 120

GATGCTCACA ACTGTATTCC TGAGCTGGAC AGCGAGACAG CCATGTTTTC TGTCTACGAT 180

GGACATGGAG GGGAGGAAGT TGCCTTGTAC TGTGCCAAAT ATCTTCCTGA CATCATCAAG 240

GATCAGAAGG CCTACAAAGA AGGCAAGCTA CAGAAGGCTT TGGAAGATGC CTTCTTGGCT 300

ATCGATGCCA AACTGACCAC TGAGGAAGTC ATTAAAGAGC TGGCACAGAT TGCAGGGCGA 360

CCCACTGAGG ATGAGGATGA AAAAGAAAAA GTAGCTGATG AAGATGATGT GGACAACGAG 420

GAGGCTGCAC TACTGCATGA AGAGGCTACC ATGACTATTG AAGAGCTGCT GACACGCTAT 480

GGGCAGAACT GTCACAAGGG TGCTCCCCAC AGCAAATCTG GAGCTGGGAC AGGCGAGGAA 540

GCAGGGTCCC AGGGCCTCAA TGGGGAGGCG GGACCTGAGG ACCCATCTAG GGAAACTTCT 600

TCAGAGGAAA ATGGCCCCAC AGCCAAGGCT CACACAGGCC TTTCCTCCAA CTCGGAACGT 660

GGGACTGAGG CAGGCCAAGG GGGTGAGCCT GGCACTCCCA CTGGTGAGGC TGGGCCTTCC 720

TGCTCTTCAG CCTCTGACAA GCTGCCTCGA GTTGCTAAGT CCAAGTTCTT TGAGGACAGT 780

GAGGATGAGT CAGATGAGGC GGAGGAGGAA GAGGAAGACA GTGAGGAATG CAGTGAGGAA 840

GAAGACGGCT ACAGCAGTGA AGAGGCAGAG AATGAGGAAG ACGAGGATGA CACTGAGGAG 900

GCTGAAGAGG ATGAGGAAGA AGAAGAGGAG ATGATGGTCC CTGGGATGGA AGGCAAAGAG 960

GAGCCTGGCT CTGACAGTGG CACAACAGCG GTGGTGGCTC TGATACGAGG GAAGCAGTTG 1020

ATTGTAGCCA ATGCAGGAGA CTCCCGCTGT GTGGTGTCTG AGGCTGGCAA AGCTTTAGAC 1080

ATGTCCTATG ACCACAAACC AGAGGATGAA GTGGAGCTGG CACGCATCAA GAATGCTGGT 1140

GGCAAGGTGA CCATGGACGG GCGAGTCAAC GGTGGCCTCA ACCTCTCCAG AGCCATTGGA 1200

GACCACTTCT ATAAGAGAAA CAAGAACTTA CCACCTGAGG AACAGATGAT TTCGGCCCTC 1260

CCTGACATCA AGGTGCTGAC TCTCACTGAT GATCACGAAT TCATGGTCAT TGCCTGTGAT 1320

GGCATCTGGA ATGTGATGAG CAGCCAGGAA GTTATAGACT TTATTCAGTC CAAGATCAGC 1380

CAGCGTGATG AAAATGGGGA GCTTCGGTTA TTGTCATCCA TCGTGGAAGA GCTGCTGGAT 1440

CAGTGCCTGG CACCAGACAC CTCTGGGGAC GGTACAGGGT GTGACAACAT GACCTGCATC 1500

ATCATATGCT TCAAGCCCCG AAACACAGCA GAGCTTCAGC CAGAGAGTGG CAAGCGGAAA 1560

CTGGAGGAGG TGCTCTCTAC TGAGGGGGCT GAAGAAAATG GCAACAGTGA CAACAAGAAG 1620

AAGGCCAAGC GGGACTAG 1638

Domain Profile

S: 87    deel..kvleeksldidksGstavvalikdsklyvanvGdSravLcrngkavelssdHkp  144

         +ee+    +e k++  + sG+tavvali++++l+van+GdSr+v +  gka+ +s dHkp

Q: 308   EEEMmvPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKP  367

         334412334455555666******************************************

S: 145   sredEleRieeaggsvilkdgaRvlGvLavsRalGdlylk.........pyvtpePevts  195

         + e El+Ri++agg+v+ +   Rv+G L++sRa+Gd ++k         +++++ P++ +

Q: 368   EDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKV  425

         *******************9..**************************************

S: 196   hrltsedefliLasDGlwdvvsneeavslvrdvle......kkeaeqeaakkLvklalar  249

          +lt ++ef+++a+DG+w+v+s++e+++++++ ++      + + ++++ ++L++++la

Q: 426   LTLTDDHEFMVIACDGIWNVMSSQEVIDFIQSKISqrdengELRLLSSIVEELLDQCLAP  485

         ********************************9998877666667788999999999999

S: 250   gsk......dnvsaiv  259

          ++      dn++ i+

Q: 486   DTSgdgtgcDNMTCII  501

         9987777777777766

Domain Sequence
(FASTA)

EEEMMVPGME GKEEPGSDSG TTAVVALIRG KQLIVANAGD SRCVVSEAGK ALDMSYDHKP 60

EDEVELARIK NAGGKVTMDG RVNGGLNLSR AIGDHFYKRN KNLPPEEQMI SALPDIKVLT 120

LTDDHEFMVI ACDGIWNVMS SQEVIDFIQS KISQRDENGE LRLLSSIVEE LLDQCLAPDT 180

SGDGTGCDNM TCII 194

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007050	; P:cell cycle arrest
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

ssc:100739632

;

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013