EKS-SUS-00053

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00053

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	392.0	1.9E-117	201	482	282

Status

Unreviewed

Ensembl Protein

ENSSSCP00000022139

UniProt Accession

I3LDK7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17

Gene Synonyms/Alias

CDK17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000028182	ENSSSCP00000022139	ENSSSCT00000032012

Organism

Sus scrofa

Functional Description

Protein Length

533

Protein Sequence
(FASTA)

FDRMKKFKRR LSLTLRGSQT IDESLSELAE QMTIEENSSK DNGYCETTEP IVKNGRPPTS 60

HSMHSFLHQY TGSFKKPPLR RPHSVIGGSL GSFMAMPRNG SRLDIVHENL KMGSDGESDQ 120

ASGTSSDEVQ SPTGVCLRNR IHRRISMEDL NKRLSLPADI RIPDGYLEKL QINSPPFDQP 180

MSRRSRRASL SEIGFGKMET YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA 240

PCTAIREVSL LKDLKHANIV TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK 300

LFLYQILRGL AYCHRRKVLH RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT 360

LWYRPPDVLL GSSEYSTQID MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPSQE 420

TWPGVSSNDE FKNYNFPKYK PQPLINHAPR LDSEGIELIT KFLQYESKKR VSAEEAMKHV 480

YFRSLGPRIH ALPESVSIFS LKEIQLQKDP GFRNSSYPET VDLESSFVYT VLF 533

Nucleotide Sequence
(FASTA)

TTTGATAGGA TGAAAAAATT TAAGAGAAGG CTATCCCTCA CCCTTCGAGG AAGCCAGACT 60

ATTGATGAAT CATTGTCTGA ATTGGCTGAG CAAATGACTA TTGAAGAAAA CAGCAGCAAG 120

GATAATGGAT ATTGTGAAAC CACAGAGCCT ATCGTGAAGA ATGGCAGGCC TCCAACCTCT 180

CACAGTATGC ATTCCTTCCT CCACCAGTAC ACGGGGTCCT TCAAGAAGCC CCCGTTGCGG 240

AGACCACATA GCGTTATTGG AGGAAGCCTT GGTTCCTTCA TGGCAATGCC CAGAAATGGA 300

AGCAGATTAG ATATTGTTCA TGAAAATCTA AAAATGGGAT CAGATGGTGA GAGTGACCAA 360

GCTTCTGGGA CATCATCTGA TGAAGTCCAG TCACCTACGG GTGTTTGTCT TAGAAATCGT 420

ATACATAGAC GGATCTCAAT GGAGGATTTA AATAAGCGGT TATCACTGCC TGCAGATATC 480

AGAATACCTG ATGGGTATCT TGAAAAGTTG CAGATAAACA GTCCACCATT TGATCAACCA 540

ATGAGCCGAA GGTCTCGGAG AGCTTCCTTA TCAGAAATTG GGTTTGGAAA AATGGAAACC 600

TACATCAAGT TAGAAAAGCT TGGAGAGGGT ACATATGCAA CAGTATATAA AGGAAGAAGT 660

AAATTGACAG AGAATTTGGT GGCATTGAAA GAGATCCGAT TGGAACATGA AGAAGGTGCG 720

CCCTGCACAG CAATAAGAGA AGTTTCACTA TTAAAGGATC TAAAACATGC AAATATTGTT 780

ACCTTACATG ACATTGTTCA CACAGATAAA TCTTTGACCC TGGTCTTTGA GTATCTGGAT 840

AAAGATCTAA AACAGTACAT GGATGACTGT GGAAACATCA TGAGTATGCA CAATGTAAAG 900

CTGTTTCTAT ACCAGATTCT ACGTGGTTTA GCATATTGCC ACAGAAGAAA GGTCTTGCAT 960

CGAGACTTAA AACCGCAGAA CCTCCTCATT AATGAAAAAG GAGAATTAAA GCTAGCAGAT 1020

TTTGGACTAG CCAGAGCCAA GTCAGTTCCC ACAAAGACCT ACTCAAATGA AGTTGTCACG 1080

CTGTGGTACC GGCCACCTGA TGTGCTTCTC GGTTCCTCAG AGTACTCAAC ACAGATTGAC 1140

ATGTGGGGTG TTGGTTGCAT TTTCTTTGAA ATGGCTTCTG GAAGACCTCT GTTTCCAGGA 1200

TCAACTGTGG AAGATGAACT GCACTTAATT TTCCGACTGT TAGGAACTCC ATCTCAGGAA 1260

ACTTGGCCAG GTGTTTCTTC AAATGATGAG TTCAAGAACT ACAACTTTCC AAAATATAAA 1320

CCACAGCCTC TAATTAACCA TGCCCCCAGG TTAGACTCTG AAGGAATTGA ATTGATAACA 1380

AAATTTCTTC AGTATGAATC TAAGAAAAGG GTTTCGGCAG AAGAGGCCAT GAAACATGTG 1440

TACTTTCGAA GTCTGGGACC AAGAATACAT GCTTTACCTG AAAGTGTGTC AATATTCAGT 1500

TTGAAAGAGA TTCAGTTGCA AAAGGACCCG GGTTTTCGAA ATTCTTCTTA TCCAGAGACA 1560

GTGGACTTGG AATCTTCGTT TGTCTACACT GTCCTCTTC 1599

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 201   YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  259

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+glay+H++k

Q: 260   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKLFLYQILRGLAYCHRRK  317

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 318   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  377

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtps+++wp+vs+  e+k ++fp

Q: 378   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKnYNFP  437

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ l ++ ++l++++++l++k+l+++ kkR+sa+ea++h yf

Q: 438   KYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF  482

         ********************************************8

Domain Sequence
(FASTA)

YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK LFLYQILRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPSQE TWPGVSSNDE FKNYNFPKYK 240

PQPLINHAPR LDSEGIELIT KFLQYESKKR VSAEEAMKHV YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013