EKS-SUS-00381

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00381

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	328.1	4.4E-98	113	361	249

Status

Unreviewed

Ensembl Protein

ENSSSCP00000023034

UniProt Accession

I3LG41;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000029264	ENSSSCP00000023034	ENSSSCT00000030606

Organism

Sus scrofa

Functional Description

Protein Length

505

Protein Sequence
(FASTA)

MPGVLEQAPV LDMPVPAEGT PPPLSGTPVP VPAYFRHAEP GFSLKKPGGL SRSLPPRPPA 60

KGSIPISRLF PLRTPGWHQP QPRRVSFRGK ASELLQSPGY DPNRPESFFQ QSFHRLGRLG 120

HGSYGEVFKV RSKEDGRLYA VKRSMSPFRG PKDRARKLAE VCGHEKVGQH PRCVRLEQAW 180

EEGGILYLQT ELCGPSLQQH CEAWGASLPE AQVWGYLRDA LLALAHLHGQ GLVHLDVKPA 240

NIFLGPRGRC KLGDFGLLVE LGASGASEAQ EGDPRYMAPE LLQGSYGTAA DVFSLGLTIL 300

EVACNMELPH GGEGWQQLRQ GYLPPEFTAG LSSELRSVLV MMLEPDPKLR ATAEALLALP 360

MLRQPRPWSV LWYMAAEALS RGWALWQALL ALLCWLWHGL AHPASWLQPL GPPATPPGSP 420

PCSLLLDSSL SSNWDDDSIG PPLAPGAAMP GSSARAAVPA GKGPAPKPRD ALDLSDIDSE 480

PPRGTFPAFE PRNLLSLFED SLGPS 505

Nucleotide Sequence
(FASTA)

ATGCCAGGGG TGCTAGAACA GGCTCCTGTG CTGGACATGC CTGTGCCTGC AGAGGGCACC 60

CCGCCGCCCC TGAGTGGCAC CCCGGTCCCG GTCCCAGCCT ACTTCCGGCA CGCAGAACCT 120

GGCTTCTCCC TCAAGAAGCC CGGGGGGCTC AGTCGGAGCC TCCCACCCCG GCCCCCTGCC 180

AAGGGCAGCA TCCCCATCAG CCGCCTCTTC CCTCTTCGGA CCCCGGGCTG GCACCAGCCT 240

CAGCCCCGGC GAGTGTCGTT CCGAGGCAAA GCCTCTGAGC TCCTGCAGAG CCCTGGGTAC 300

GACCCGAATC GGCCGGAGTC CTTCTTCCAG CAGAGTTTCC ACAGGCTTGG CCGCCTAGGC 360

CACGGCTCCT ATGGAGAAGT CTTCAAGGTG CGCTCCAAGG AAGATGGCCG GCTCTACGCG 420

GTGAAGCGCT CCATGTCCCC ATTCCGGGGC CCCAAGGACC GGGCCCGCAA GCTGGCCGAG 480

GTCTGCGGCC ACGAGAAGGT GGGGCAGCAC CCGCGCTGCG TGCGGCTGGA ACAGGCCTGG 540

GAGGAGGGCG GCATCCTGTA CCTGCAGACG GAGCTGTGTG GGCCCAGCCT GCAGCAGCAC 600

TGCGAGGCCT GGGGTGCCAG CCTGCCCGAG GCCCAGGTCT GGGGCTACCT GAGGGATGCC 660

CTGCTGGCCC TGGCCCACCT GCATGGCCAA GGCCTGGTCC ACCTTGACGT CAAGCCTGCC 720

AACATCTTCC TGGGGCCCCG GGGCCGCTGC AAGCTGGGTG ACTTTGGGTT GCTGGTGGAG 780

CTGGGTGCAT CTGGAGCCAG CGAGGCCCAG GAGGGAGACC CGCGCTACAT GGCCCCCGAG 840

CTGCTGCAAG GCTCTTACGG GACAGCGGCC GACGTATTCA GTCTGGGCCT CACCATCTTG 900

GAAGTGGCGT GCAACATGGA GCTGCCCCAT GGTGGGGAGG GCTGGCAGCA GCTGCGCCAG 960

GGCTACCTGC CCCCCGAATT CACTGCTGGC CTGTCTTCTG AGCTGCGGTC TGTCCTCGTC 1020

ATGATGCTGG AACCTGACCC CAAGCTGCGG GCCACAGCCG AGGCCCTGCT GGCCCTGCCC 1080

ATGCTCCGGC AGCCACGGCC TTGGAGCGTC CTGTGGTACA TGGCCGCTGA AGCCCTCAGC 1140

CGAGGGTGGG CCCTGTGGCA GGCCCTGCTC GCCCTGCTCT GCTGGCTCTG GCACGGGCTG 1200

GCTCACCCCG CCAGCTGGCT GCAGCCTCTA GGTCCGCCGG CCACCCCGCC TGGCTCGCCG 1260

CCCTGCAGCC TCCTCCTGGA CAGCAGCCTC TCCAGCAACT GGGATGACGA CAGCATAGGG 1320

CCACCTCTTG CTCCGGGTGC TGCCATGCCA GGGAGCAGTG CCCGGGCCGC GGTGCCTGCT 1380

GGGAAAGGCC CTGCCCCCAA GCCCAGGGAT GCTCTGGACC TAAGTGACAT TGACTCAGAG 1440

CCACCTCGGG GCACCTTCCC CGCCTTTGAG CCTCGGAACC TCCTCAGCCT GTTTGAGGAC 1500

TCACTGGGCC CCAGCTGA 1518

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++ ++G+G++gevfkv+++edg+lyA+k+s++p++g ++++++l+Ev +h+++gqh+

Q: 113   FHRLGRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVCGHEKVGQHPR  172

         89999*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +vr+ +aWee ++ly+qtElC g sL+++   cea+ ++l+ea+++ +l d ll+l +lH

Q: 173   CVRLEQAWEEGGILYLQTELC-GPSLQQH---CEAWGASLPEAQVWGYLRDALLALAHLH  228

         *********************.*******...****************************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

          + lvHlD+kp+nif+  ++++klgD+Gl++el+++ +s+++EGD ry+a+E+lq++y +

Q: 229   GQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGASGASEAQEGDPRYMAPELLQGSYGT  288

         ************************************************************

S: 181   lkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepdp  240

         + aD+Fslgltileva+n+elP+ Ge W++lR+g+lp+e+++ ls++lr++l +mlepdp

Q: 289   A-ADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDP  347

         *.**********************************************************

S: 241   erRptaeellkhev  254

         + R+tae+ll+ ++

Q: 348   KLRATAEALLALPM  361

         **********9876

Domain Sequence
(FASTA)

FHRLGRLGHG SYGEVFKVRS KEDGRLYAVK RSMSPFRGPK DRARKLAEVC GHEKVGQHPR 60

CVRLEQAWEE GGILYLQTEL CGPSLQQHCE AWGASLPEAQ VWGYLRDALL ALAHLHGQGL 120

VHLDVKPANI FLGPRGRCKL GDFGLLVELG ASGASEAQEG DPRYMAPELL QGSYGTAADV 180

FSLGLTILEV ACNMELPHGG EGWQQLRQGY LPPEFTAGLS SELRSVLVMM LEPDPKLRAT 240

AEALLALPM 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013