EKS-SUS-00339

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SUS-00339

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	366.8	9.5E-110	353	613	261

Status

Unreviewed

Ensembl Protein

ENSSSCP00000027585

UniProt Accession

I3LNQ4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K2

Gene Synonyms/Alias

MAP3K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSSCG00000030354	ENSSSCP00000027585	ENSSSCT00000022881
ENSSSCG00000030354	ENSSSCP00000025729	ENSSSCT00000030086

Organism

Sus scrofa

Functional Description

Protein Length

616

Protein Sequence
(FASTA)

LDDQQALNSI MQDLAVLHKV YFQNDVRVKF EHRGEKRILQ FPRPVKLEDL RSKAKIAFGQ 60

SMDLHYTNNE LVIPLTTQDD LDKAVELLDR SIHMKSLKIL LQHLNRILIN SSPSLCSNLL 120

QSFFIYPGAV NMVIKDSMET CEGGLKEEVE EMKQMKGGGP TSRDRSSPPP GYIPDELHQV 180

ARNGSFTSIN SEGEFIPESM DQVSSPENSG SGSCPSLDSP LDGESYPKSR MPRAQSYPDN 240

HQEFSDYDNP IFEKFGKGGT YPRRYHVSYH HQDYNDGRKT FPRARRTQGT SFRSPVSFSP 300

TDHSLSTSSG SSIFTPEYDE NRLRRRGSDI DNPTLTVMDI SPPSRSPRAP TNWRLGKLLG 360

QGAFGRVYLC YDVDTGRELA VKQVQFDPDS PETSKEVNAL ECEIQLLKNL LHERIVQYYG 420

CLRDPQEKTL SIFMEYMPGG SIKDQLKAYG ALTENVTRKY TRQILEGVHY LHSNMIVHRD 480

IKGANILRDS TGNVKLGDFG ASKRLQTICL SGTGMKSVTG TPYWMSPEVI SGEGYGRKAD 540

IWSVGCTVVE MLTEKPPWAE FEAMAAIFKI ATQPTNPKLP PHVSDYTRDF LKRIFVEAKL 600

RPSADELLRH MFVHYH 616

Nucleotide Sequence
(FASTA)

CTAGATGATC AGCAAGCTTT GAACTCAATC ATGCAAGATT TGGCTGTTCT TCATAAGGTA 60

TATTTTCAGA ATGATGTCCG AGTCAAATTT GAACACAGAG GAGAAAAAAG AATCCTTCAG 120

TTCCCCAGAC CAGTTAAACT GGAAGATCTG AGGTCTAAAG CTAAAATTGC CTTTGGACAG 180

TCTATGGATC TACATTATAC CAATAATGAG TTGGTAATCC CATTAACTAC CCAAGATGAC 240

TTGGACAAAG CTGTGGAACT GCTTGATCGC AGTATTCACA TGAAGAGTCT CAAGATACTA 300

CTTCAGCACC TGAACAGAAT CCTGATAAAT AGCAGTCCAT CTCTATGCTC TAATTTACTT 360

CAGTCTTTCT TTATATATCC AGGGGCAGTG AATATGGTCA TTAAAGATAG CATGGAAACG 420

TGTGAGGGTG GGTTGAAGGA AGAAGTAGAA GAGATGAAAC AGATGAAGGG AGGAGGTCCC 480

ACTAGTAGAG ATAGAAGCTC CCCTCCCCCT GGATACATTC CAGATGAATT GCACCAGGTT 540

GCCCGGAATG GGTCGTTCAC CAGTATCAAC AGTGAAGGAG AGTTCATTCC AGAGAGCATG 600

GACCAAGTAA GCAGCCCTGA AAATTCTGGC TCAGGAAGTT GTCCATCACT TGATAGCCCT 660

TTGGATGGAG AGAGCTATCC AAAATCACGA ATGCCTAGGG CACAGAGCTA CCCGGATAAT 720

CATCAGGAAT TTTCAGACTA CGATAACCCT ATCTTTGAGA AATTTGGAAA AGGAGGAACA 780

TATCCAAGAA GGTATCATGT TTCATATCAC CATCAAGACT ATAATGATGG GCGTAAAACT 840

TTCCCAAGAG CTAGAAGGAC CCAGGGAACC AGCTTCCGGT CTCCTGTGAG TTTCAGTCCT 900

ACTGACCACT CCTTAAGCAC TAGTAGTGGA AGCAGCATCT TTACCCCAGA GTATGATGAG 960

AATCGATTAA GAAGAAGGGG AAGTGATATA GACAATCCTA CTCTGACTGT CATGGACATC 1020

AGCCCACCCA GCCGCTCACC TCGTGCTCCA ACCAACTGGA GATTGGGCAA ACTGCTTGGC 1080

CAGGGAGCTT TTGGCAGAGT CTACCTCTGT TATGATGTTG ACACAGGAAG AGAATTGGCT 1140

GTTAAGCAAG TTCAGTTTGA CCCAGATAGC CCTGAAACCA GCAAGGAAGT AAACGCACTT 1200

GAGTGTGAAA TTCAGTTGTT GAAAAACTTG CTGCATGAGC GAATTGTTCA GTATTATGGC 1260

TGTTTGAGGG ATCCCCAAGA AAAAACACTT TCCATATTTA TGGAATATAT GCCAGGGGGT 1320

TCAATTAAGG ACCAATTAAA AGCATATGGA GCTCTTACTG AGAACGTGAC TAGGAAATAC 1380

ACCCGTCAGA TTCTGGAGGG TGTCCATTAT TTGCACAGTA ATATGATTGT TCATAGAGAT 1440

ATAAAAGGCG CAAATATTCT GCGAGATTCA ACAGGCAACG TCAAACTAGG AGATTTTGGG 1500

GCCAGCAAAC GGCTTCAAAC CATCTGTCTT TCGGGGACAG GAATGAAGTC TGTCACAGGC 1560

ACGCCATATT GGATGAGCCC TGAAGTGATT AGTGGAGAAG GTTATGGCAG AAAAGCAGAT 1620

ATCTGGAGCG TGGGCTGCAC TGTGGTGGAA ATGCTAACTG AAAAACCTCC TTGGGCAGAA 1680

TTTGAAGCAA TGGCTGCCAT CTTTAAAATT GCCACTCAGC CAACGAACCC AAAGCTGCCA 1740

CCTCACGTCT CAGACTATAC TCGAGATTTC CTCAAACGGA TCTTTGTAGA GGCCAAACTG 1800

AGACCCTCAG CTGATGAACT TCTAAGGCAC ATGTTTGTGC ACTATCACTA G 1851

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++dvdtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 353   WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  412

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  + +e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg++yLH

Q: 413   ERIVQYYGClrDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH  472

         *********777899*********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 473   SNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  532

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs+gc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s+ ++d

Q: 533   E--GYGRKADIWSVGCTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPKLPPHVSDYTRD  589

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         fl++++ +++k rpsa+eLL+h+f+

Q: 590   FLKRIF-VEAKLRPSADELLRHMFV  613

         ******.899*************96

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD VDTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGCL RDPQEKTLSI FMEYMPGGSI KDQLKAYGAL TENVTRKYTR QILEGVHYLH 120

SNMIVHRDIK GANILRDSTG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVGCTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPKLPPH VSDYTRDFLK 240

RIFVEAKLRP SADELLRHMF V 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013