EKS-ICT-00145

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00145

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	522.0	4.0E-157	90	383	294

Status

Unreviewed

Ensembl Protein

ENSSTOP00000001201

UniProt Accession

I3LYE5;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000001333	ENSSTOP00000001201	ENSSTOT00000001341

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

473

Protein Sequence
(FASTA)

MAMTAGTTTT FPMSNHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE VAMEEEGLAD 60

EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLTEEET QFYISETVLA IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SEKAKDLILR 360

FCTDSENRIG NSGVEEIKSH PFFEGVDWGH IRERPAAIPI EIKSIDDTSN FDDFPESDIL 420

QPGKVNFSIF LVPNTTEPDY KSKDWVFLNY TYKRFEGLTQ RGSIPTYMKA GKL 473

Nucleotide Sequence
(FASTA)

ATGGCAATGA CGGCAGGGAC TACAACAACC TTTCCTATGA GCAACCATAC CCGGGAAAGA 60

GTGACTGTAG CCAAGCTCAC ATTGGAAAAT TTTTACAGCA ATCTAATTTT ACAGCATGAA 120

GAAAGAGAAA CCAGGCAGAA GAAATTAGAA GTGGCCATGG AAGAAGAAGG ATTAGCAGAT 180

GAAGAGAAAA AATTACGCCG ATCACAACAT GCTCGCAAGG AAACAGAGTT TTTACGGCTC 240

AAGAGGACCA GGCTTGGCTT GGATGACTTT GAGTCTCTGA AAGTTATAGG AAGAGGAGCT 300

TTTGGAGAGG TACGGCTGGT CCAAAAAAAA GATACAGGAC ATATCTATGC AATGAAGATA 360

TTGAGAAAGG CTGATATGCT TGAAAAAGAA CAGGTGGCAC ATATCCGAGC AGAAAGAGAT 420

ATTTTGGTGG AAGCAGATGG TGCCTGGGTG GTGAAGATGT TTTATAGTTT TCAGGATAAG 480

AGGAACCTTT ATCTCATCAT GGAATTTCTT CCTGGAGGTG ACATGATGAC ATTGTTAATG 540

AAGAAGGATA CCTTGACAGA AGAGGAAACA CAGTTCTACA TTTCAGAGAC TGTTCTGGCA 600

ATAGATGCAA TCCACCAGTT GGGCTTCATC CATCGGGATA TCAAGCCAGA CAACCTTTTA 660

TTGGATGCCA AGGGACATGT AAAATTATCT GATTTTGGTT TGTGCACGGG GTTAAAGAAA 720

GCTCACAGGA CTGAATTCTA CAGGAATCTT ACACACAACC CACCAAGTGA CTTCTCATTT 780

CAGAACATGA ACTCAAAGAG GAAAGCGGAA ACATGGAAGA AAAACAGGAG ACAACTGGCA 840

TATTCCACAG TTGGGACACC AGATTACATT GCTCCAGAAG TCTTCATGCA GACTGGTTAC 900

AACAAGTTGT GTGACTGGTG GTCTTTGGGA GTGATTATGT ATGAAATGTT AATAGGCTAT 960

CCACCTTTCT GCTCCGAAAC GCCTCAAGAA ACATACAGAA AAGTGATGAA TTGGAAAGAA 1020

ACTCTAGTAT TTCCTCCAGA AGTACCTATC TCTGAGAAAG CCAAGGATTT AATTCTCAGA 1080

TTTTGTACTG ATTCTGAAAA TAGAATTGGG AATAGTGGAG TAGAAGAAAT AAAAAGTCAC 1140

CCCTTTTTTG AAGGTGTAGA CTGGGGGCAT ATAAGGGAAA GGCCAGCAGC AATCCCTATA 1200

GAAATCAAGA GCATTGATGA CACTTCAAAT TTTGATGACT TCCCTGAATC TGATATCTTA 1260

CAACCAGGTA AGGTTAATTT TTCTATCTTT TTAGTGCCAA ATACCACAGA ACCAGACTAT 1320

AAATCCAAAG ACTGGGTCTT TCTCAATTAT ACCTACAAAA GGTTTGAAGG GTTGACTCAG 1380

CGTGGCTCTA TCCCCACCTA CATGAAAGCT GGGAAATTAT GA 1422

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++d+e+r+g++Gv+eik+hpff

Q: 330   ETYRKVMNWKETLVFPPEVPISEKAKDLILRFCTDSENRIGNSGVEEIKSHPFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL RFCTDSENRI GNSGVEEIKS HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013