EKS-ICT-00456

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00456

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	570.9	3.2E-172	2	253	252

Status

Unreviewed

Ensembl Protein

ENSSTOP00000022466

UniProt Accession

I3NDL9;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK2D

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000001689	ENSSTOP00000022466	ENSSTOT00000020840
ENSSTOG00000001689	ENSSTOP00000001520	ENSSTOT00000001697

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

514

Protein Sequence
(FASTA)

VSRGAFSVVR RCMKIPTGQE YAAKIINTKK LSARDHQKLE REARICRLLK HPNIVRLHDS 60

ISEEGFHYLV FDLVTGGELF EDIVAREYYS EADASHCIQQ ILEAVLHCHQ MGVVHRDLKP 120

ENLLLASKSK GAAVKLADFG LAIEVQGDQQ AWFGFAGTPG YLSPEVLRKD PYGKPVDMWA 180

CGVILYILLV GYPPFWDEDQ HRLYQQIKAG AYDFPSPEWD TVTPEAKDLI NKMLTINPAK 240

RITASEALKH PWICQRSTVA SMMHRQETVD CLKKFNARRK LKGAILTTML ATRNFSAAKS 300

LLKKPDGVKI NNKANVVTSP KENIPTPALE PQTTVIHNPD GNKESTESSN TTIEDEDVKA 360

RKQEIIKVTE QLIEAINNGD FEAYTKICDP GLTAFEPEAL GNLVEGMDFH RFYFENALSK 420

SNKPIHTIIL NPHVHLVGDD AACIAYIRLT QYMDGSGMPK TMQSEETRVW HRRDGKWQNV 480

HFHRSGSPTV PIKPPCIPNG KENFSGGTSL WQNI 514

Nucleotide Sequence
(FASTA)

GTTTCCAGGG GGGCATTCTC AGTGGTCAGA AGATGTATGA AAATCCCTAC TGGACAAGAG 60

TATGCTGCCA AAATTATCAA CACCAAAAAG CTTTCTGCTA GGGATCATCA GAAACTGGAA 120

AGGGAAGCTA GAATCTGCCG TCTTTTGAAG CACCCTAATA TTGTGAGACT TCATGACAGC 180

ATATCGGAAG AGGGCTTCCA TTACTTGGTG TTTGATTTAG TTACTGGAGG TGAACTATTT 240

GAAGACATAG TGGCAAGAGA ATATTACAGT GAAGCTGATG CCAGTCATTG CATTCAGCAG 300

ATCCTGGAGG CTGTGCTACA CTGCCATCAG ATGGGCGTAG TCCATCGGGA CCTGAAGCCT 360

GAGAATTTGC TTTTAGCTAG CAAATCCAAG GGAGCAGCTG TGAAACTGGC AGACTTTGGC 420

TTAGCCATTG AAGTTCAAGG AGACCAGCAG GCATGGTTTG GTTTTGCTGG CACACCTGGA 480

TATCTTTCTC CAGAAGTTTT ACGTAAAGAT CCTTATGGAA AACCAGTGGA TATGTGGGCA 540

TGTGGTGTCA TTCTCTATAT CCTACTGGTG GGGTATCCAC CTTTCTGGGA TGAAGACCAA 600

CACAGACTCT ACCAGCAGAT CAAGGCTGGA GCTTATGATT TTCCATCACC AGAATGGGAC 660

ACAGTGACTC CTGAAGCCAA AGACCTCATC AATAAAATGC TTACCATCAA CCCTGCCAAA 720

CGCATCACAG CCTCAGAAGC ACTGAAACAT CCATGGATCT GTCAACGTTC CACTGTGGCT 780

TCCATGATGC ACAGACAGGA GACTGTGGAC TGCTTGAAGA AATTCAATGC TAGACGAAAA 840

CTAAAGGGTG CCATTTTGAC AACTATGTTG GCTACGAGAA ATTTTTCAGC AGCCAAGAGT 900

TTGTTGAAGA AACCAGATGG AGTAAAGATA AACAACAAAG CCAACGTGGT AACCAGCCCC 960

AAAGAAAATA TTCCCACCCC GGCGCTGGAG CCCCAAACTA CTGTAATCCA CAACCCTGAT 1020

GGAAACAAGG AGTCAACTGA GAGTTCAAAT ACAACAATTG AGGATGAAGA TGTGAAAGCA 1080

CGAAAGCAAG AGATTATCAA GGTCACTGAA CAACTGATTG AAGCCATCAA TAATGGGGAC 1140

TTCGAAGCTT ACACAAAAAT CTGTGACCCG GGTCTTACTG CCTTTGAACC TGAAGCTTTG 1200

GGTAACTTAG TGGAAGGGAT GGATTTTCAC CGATTCTACT TTGAAAATGC TTTGTCCAAA 1260

AGCAATAAAC CAATCCACAC TATTATCCTA AATCCTCATG TCCATCTGGT CGGGGACGAT 1320

GCTGCCTGCA TAGCATACAT TAGGCTCACA CAGTACATGG ATGGCAGTGG AATGCCAAAG 1380

ACAATGCAGT CAGAAGAGAC CCGCGTGTGG CACCGCAGGG ATGGAAAGTG GCAGAATGTT 1440

CATTTTCATC GCTCGGGGTC ACCAACAGTA CCCATCAAGC CACCATGTAT TCCAAATGGG 1500

AAAGAAAACT TCTCAGGAGG CACCTCTTTG TGGCAAAACA TCTAA 1545

Domain Profile

S: 8     gkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsi  67

          +gafsvvrrc+k+ tgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsi

Q: 2     SRGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSI  61

         68**********************************************************

S: 68    seegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvvhrdlkpe  127

         seegfhylvfdlvtggelfedivareyyseadashciqqile+vlh+hq+gvvhrdlkpe

Q: 62    SEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPE  121

         ************************************************************

S: 128   nlllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpvdlwac  187

         nlllask+kgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpvd+wac

Q: 122   NLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC  181

         ************************************************************

S: 188   gvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakr  247

         gvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakr

Q: 182   GVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKR  241

         ************************************************************

S: 248   itadealkhpwi  259

         ita+ealkhpwi

Q: 242   ITASEALKHPWI  253

         ***********8

Domain Sequence
(FASTA)

SRGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI 60

SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LEAVLHCHQM GVVHRDLKPE 120

NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKDP YGKPVDMWAC 180

GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT VTPEAKDLIN KMLTINPAKR 240

ITASEALKHP WI 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013