EPS-ICT-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ICT-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	209.8	5.6E-62	57	314	258

Status

Unreviewed

Ensembl Protein

ENSSTOP00000023733

UniProt Accession

I3N876;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1N

Gene Synonyms/Alias

PPM1N;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000002827	ENSSTOP00000020572	ENSSTOT00000027133
ENSSTOG00000002827	ENSSTOP00000023733	ENSSTOT00000002832

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

402

Protein Sequence
(FASTA)

MAALAGLLEC LLWPTRKDEE AEKEEEAGAQ GPQSLLAAPR CSQRPHGGVA ASSGLRFGAS 60

AAQGWRTHME DAHCAWLSLP GLPPGWAFFA ILDGHGGARV ARFGARHLPG HVLEELGPAP 120

SEPEGVSQAL RRAFLNADER LRSLWPRGEP GGSTAVVLLV SPRFLYLAHC GDSRAVLSRA 180

GAVAFSTQDH RPLRLRERER IYHAGGTIRR RRVEGSLAVS RALGDFAYKA APGRPPELQL 240

ISAEPEVAAL ARHTEDEFVL LASDGVWDVM SGAALVGLVA LRLRLDLAPE LLCAQLLDTC 300

LCKGSLDNMT CIVVCFPGAP RACEEAIRRE HALDTALGRR VAELCASAQE PPSLNTVFRT 360

LASEDILDLP PGGGLHCKAA VIAEAYSQLF QASEECWENE QW 402

Nucleotide Sequence
(FASTA)

ATGGCGGCCC TTGCAGGTCT GCTGGAGTGT CTCCTCTGGC CGACTCGCAA GGATGAAGAG 60

GCAGAGAAGG AAGAGGAAGC TGGCGCCCAA GGGCCTCAGT CTCTCCTGGC TGCGCCGCGA 120

TGCTCCCAGA GGCCACACGG GGGTGTGGCA GCATCGTCCG GCCTGCGCTT CGGAGCCAGC 180

GCAGCGCAGG GTTGGCGAAC GCACATGGAG GACGCGCACT GCGCTTGGCT CTCCTTACCT 240

GGGCTGCCGC CTGGCTGGGC TTTCTTCGCT ATCCTCGACG GCCACGGAGG GGCGCGAGTT 300

GCCCGCTTCG GCGCGCGCCA CCTGCCAGGC CACGTGCTCG AAGAGCTAGG CCCAGCGCCT 360

AGCGAACCCG AGGGCGTGAG CCAGGCGCTG CGCCGAGCCT TCTTGAATGC CGACGAGCGG 420

CTCCGCTCGC TCTGGCCCCG TGGCGAACCC GGCGGCTCCA CTGCGGTCGT GTTGCTGGTC 480

TCCCCGCGCT TTCTATACCT GGCGCACTGC GGTGACTCGC GCGCGGTGCT GAGCCGCGCC 540

GGCGCCGTGG CCTTCAGCAC CCAAGACCAC CGGCCCCTCC GGCTGCGGGA ACGCGAGCGC 600

ATCTACCACG CGGGCGGCAC CATCCGTCGC CGTCGCGTCG AGGGCTCTCT GGCAGTGTCT 660

CGAGCACTAG GCGATTTTGC TTACAAAGCG GCTCCGGGGA GGCCCCCCGA ACTGCAGCTA 720

ATTTCCGCGG AGCCTGAAGT GGCTGCCCTG GCACGCCACA CTGAGGACGA ATTCGTGCTC 780

CTGGCCTCTG ACGGCGTGTG GGACGTTATG TCTGGTGCTG CGCTGGTGGG ACTGGTGGCA 840

TTGCGCCTCC GTTTGGACCT GGCCCCAGAG CTTCTCTGCG CGCAGCTGTT GGACACGTGT 900

CTGTGCAAGG GCAGCCTGGA CAACATGACC TGCATCGTGG TTTGCTTCCC AGGGGCTCCC 960

AGGGCTTGTG AGGAGGCCAT CAGGAGGGAG CATGCGCTGG ATACAGCCCT GGGCCGCAGA 1020

GTAGCTGAGC TGTGTGCCTC TGCTCAGGAG CCCCCCAGTC TGAACACAGT TTTCAGGACT 1080

CTGGCCTCGG AGGACATCCT GGATTTGCCT CCTGGGGGAG GACTGCACTG CAAGGCTGCA 1140

GTCATTGCTG AAGCTTATTC TCAGCTCTTC CAGGCCTCAG AAGAATGTTG GGAGAATGAG 1200

CAATGG 1206

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         +g ++ +g+r +meda+ +  ++   p     +aff++ DGhgg +va+f + +l  ++

Q: 57    FGASAAQGWRTHMEDAHCAWLSLPGLPPG---WAFFAILDGHGGARVARFGARHLPGHVL  113

         68899************876666665555...****************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         eel    se + v++al++aFl+ de+l    +   + ++ Gstavv l+++  ly a++

Q: 114   EELGPAPSEPEGVSQALRRAFLNADERL---RSLWPRGEPGGSTAVVLLVSPRFLYLAHC  170

         ****999*********************...444456999********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSravL+r g +   ++dH+p r +E+eRi +agg++ ++   Rv G+LavsRalGd+

Q: 171   GDSRAVLSRAGAVAFSTQDHRPLRLRERERIYHAGGTIRRR---RVEGSLAVSRALGDFA  227

         ************9**************************99...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         +++++ePev    ++ edef+ LasDG+wdv+s  ++v lv  +l+ +

Q: 228   YKaapgrppelQLISAEPEVAALARHTEDEFVLLASDGVWDVMSGAALVGLVALRLRLDL  287

         ************************************************************

S: 234   aeqeaakkLvklalargskdnvsaivv  260

         a++  + +L++++l +gs dn++ ivv

Q: 288   APELLCAQLLDTCLCKGSLDNMTCIVV  314

         ***********************9997

Domain Sequence
(FASTA)

FGASAAQGWR THMEDAHCAW LSLPGLPPGW AFFAILDGHG GARVARFGAR HLPGHVLEEL 60

GPAPSEPEGV SQALRRAFLN ADERLRSLWP RGEPGGSTAV VLLVSPRFLY LAHCGDSRAV 120

LSRAGAVAFS TQDHRPLRLR ERERIYHAGG TIRRRRVEGS LAVSRALGDF AYKAAPGRPP 180

ELQLISAEPE VAALARHTED EFVLLASDGV WDVMSGAALV GLVALRLRLD LAPELLCAQL 240

LDTCLCKGSL DNMTCIVV 258

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0008152	; P:metabolic process

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013