EKS-ICT-00406

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00406

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	535.6	2.2E-161	32	289	258

Status

Unreviewed

Ensembl Protein

ENSSTOP00000002835

UniProt Accession

I3M1T3;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000003174	ENSSTOP00000002835	ENSSTOT00000003174

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

366

Protein Sequence
(FASTA)

IVFFSPFKQL HSTSQNINLG PTGNPHAKPT DFDFLKVIGK GSFGKVLLAK RKLDGKFYAV 60

KVLQKKIVLN RKEQKHIMAE RNVLLKNVKH PFLVGLHYSF QTTEKLYFVL DFINGGELFF 120

HLQRERSFPE HRARFYAAEI ASALGYLHSI KIVYRDLKPE NILLDSVGHV VLTDFGLCKE 180

GIAISDTTTT FCGTPEYLAP EVIRKQPYDN TVDWWCLGAV LYEMLYGLPP FYCRDVAEMY 240

DNILHKPLSL RPGVSLTAWS ILEELLEKDR QNRLGAKEDF LEIQNHPFFE SLSWTDLVQK 300

KIPPPFNPNV AGPDDIRNFD TVFTEETVPY SVCVSSDYSI VNASVLEADD AFVGFSYAPP 360

SEDLFL 366

Nucleotide Sequence
(FASTA)

ATTGTTTTTT TCTCCCCATT CAAACAGCTA CACTCTACCT CACAGAACAT CAACCTGGGA 60

CCAACTGGAA ATCCTCATGC AAAGCCAACT GACTTTGATT TTTTAAAAGT TATTGGAAAA 120

GGCAGCTTTG GCAAGGTTCT TCTTGCAAAA CGGAAACTGG ATGGAAAATT TTATGCTGTC 180

AAAGTATTAC AGAAAAAAAT AGTTCTCAAC AGAAAAGAGC AAAAACATAT TATGGCCGAA 240

CGTAATGTAC TCTTGAAAAA TGTGAAACAT CCATTTTTGG TTGGATTACA TTATTCTTTC 300

CAAACAACTG AAAAACTTTA TTTTGTTCTG GATTTTATTA ATGGAGGGGA GCTGTTTTTT 360

CACTTACAAA GAGAACGGTC CTTTCCTGAA CACAGAGCAA GGTTTTATGC TGCTGAAATT 420

GCCAGTGCAT TGGGTTACTT GCACTCCATC AAAATAGTGT ACAGAGACTT AAAGCCAGAA 480

AATATTCTTT TGGATTCAGT GGGACATGTT GTCTTAACAG ATTTTGGGCT TTGTAAAGAA 540

GGAATTGCTA TTTCTGATAC TACCACCACA TTTTGTGGGA CTCCAGAGTA CCTTGCACCT 600

GAAGTAATCA GAAAACAGCC CTATGACAAC ACTGTGGATT GGTGGTGCCT TGGTGCTGTT 660

CTGTATGAAA TGCTGTATGG ATTGCCTCCT TTTTACTGCC GAGATGTTGC TGAAATGTAT 720

GATAATATTC TTCACAAGCC TCTAAGTTTG AGGCCAGGAG TGAGCCTCAC AGCCTGGTCC 780

ATTCTGGAAG AACTCCTAGA AAAAGACAGA CAAAATCGAC TTGGGGCCAA AGAAGACTTT 840

CTTGAAATTC AGAATCATCC TTTTTTTGAA TCACTTAGCT GGACTGACCT TGTACAAAAG 900

AAAATTCCAC CACCATTTAA TCCTAATGTG GCTGGACCAG ATGATATCAG GAACTTTGAT 960

ACAGTATTTA CAGAGGAAAC TGTTCCATAT TCTGTATGTG TATCTTCTGA CTATTCTATA 1020

GTGAATGCCA GTGTACTGGA GGCTGATGAT GCATTTGTTG GTTTTTCATA TGCACCTCCT 1080

TCAGAAGACT TATTTTTGTG A 1101

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk++l++ke+khimaernvllknvkhp

Q: 32    FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP  91

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld++nggelffhlqrersf+e+rarfyaaeiasalgylhs++

Q: 92    FLVGLHYSFQTTEKLYFVLDFINGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIK  151

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds ghvvltdfglcke+i+++dtt+tfcgtpeylapev+rk+pyd+t

Q: 152   IVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNT  211

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemydnil+kpl+l+pg+s++a+++leellekdr+

Q: 212   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQ  271

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgakedflei+nh+ff

Q: 272   NRLGAKEDFLEIQNHPFF  289

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKIVLNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FINGGELFFH LQRERSFPEH RARFYAAEIA SALGYLHSIK 120

IVYRDLKPEN ILLDSVGHVV LTDFGLCKEG IAISDTTTTF CGTPEYLAPE VIRKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYD NILHKPLSLR PGVSLTAWSI LEELLEKDRQ 240

NRLGAKEDFL EIQNHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013