EKS-ICT-00196

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00196

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	453.4	2.8E-136	4	285	282

Status

Unreviewed

Ensembl Protein

ENSSTOP00000004552

UniProt Accession

I3M5F1;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000005061	ENSSTOP00000004552	ENSSTOT00000005072

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

418

Protein Sequence
(FASTA)

LTDYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQHFE SIEQVNNLRE VQALRRLNPH 60

PNILTLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRHPL SEKKIRHYMY QLCRSLDHMH 120

RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT 180

YKMDLWSAGC VFYEIASLQP LFPGANELDQ ISKIHDVIGT PAQKTLTKFK QSRAMSFDFP 240

FKKGSGIPQL TTTLSPQCLS LLHAMVAYDP DERIAAHQAL LHPYFQEQRV TEKHALASHR 300

RAFFPEHPMG PELLGLNGQF SKEGRRQKQP LRQEEDHGKR RGPACLMELP KLRLSGVTKL 360

SYSSPTLQSV FSSGTNGRVP MLRPLKCLGA NKKIDTQKDI KPSLKQCRLP TIDRRGGG 418

Nucleotide Sequence
(FASTA)

CTTACAGACT ATAAAGCAAT TGGCAAAATA GGAGAGGGAA CATTTTCTGA AGTCATGAAG 60

ATGCAGAGCC TGAGAGATGG AAACTACTAT GCGTGTAAGC AAATGAAACA GCACTTTGAA 120

AGTATTGAGC AGGTGAACAA CCTACGAGAG GTACAAGCAC TGAGGCGTCT GAATCCACAC 180

CCAAACATTC TTACGTTGCA TGAAGTAGTT TTTGACAGAA AATCTGGTTC TCTTGCACTT 240

ATATGTGAAC TTATGGACAT GAATATTTAT GAGCTTATAC GAGGAAGAAG ACATCCATTA 300

TCAGAAAAAA AAATCAGGCA CTATATGTAT CAGTTATGCA GATCCCTTGA TCACATGCAC 360

AGAAATGGAA TATTTCACAG AGATGTAAAA CCAGAAAATA TACTCATAAA GCAGGATGTC 420

CTGAAACTGG GGGACTTTGG GTCCTGCCGG AGTGTCTATT CCAAGCAGCC GTACACGGAA 480

TACATCTCCA CCCGCTGGTA CCGGGCCCCG GAGTGTCTCC TCACTGATGG CTTCTACACA 540

TACAAGATGG ACCTGTGGAG TGCAGGATGT GTGTTCTATG AGATCGCCAG TCTGCAGCCC 600

CTCTTCCCTG GAGCAAATGA ACTGGACCAG ATCTCAAAAA TCCATGATGT CATTGGCACA 660

CCCGCTCAGA AGACCCTCAC CAAGTTCAAA CAGTCGAGAG CTATGAGTTT TGATTTTCCT 720

TTTAAAAAGG GATCAGGAAT ACCTCAACTG ACAACCACTT TGTCCCCGCA ATGTCTCTCC 780

CTCCTGCACG CAATGGTGGC CTATGACCCT GACGAGCGCA TCGCTGCCCA CCAGGCCCTG 840

CTGCATCCCT ACTTCCAGGA GCAGAGGGTG ACTGAGAAGC ATGCCCTGGC CAGCCACAGA 900

AGGGCTTTCT TTCCAGAGCA CCCCATGGGG CCCGAACTAC TTGGTCTCAA CGGGCAGTTC 960

TCAAAGGAGG GCAGAAGGCA GAAACAGCCC CTGAGGCAAG AGGAGGACCA CGGCAAGAGA 1020

CGGGGACCGG CCTGCCTGAT GGAACTGCCC AAATTGAGGC TTTCGGGAGT GACCAAGCTG 1080

TCATACTCCA GCCCCACACT GCAGTCAGTG TTCAGTTCTG GGACGAACGG AAGAGTCCCC 1140

ATGTTGAGAC CCTTGAAGTG CTTGGGTGCC AACAAGAAGA TAGACACACA GAAGGACATC 1200

AAGCCTAGCC TGAAACAGTG CCGCCTGCCC ACCATCGACA GGAGAGGCGG AGGG 1254

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i k+G+Gtf+ev++++sl++g+++a+k+mk++fes+e+v+nlrev++l++ln+h+ni

Q: 4     YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREVQALRRLNPHPNI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+ev++dr+++sl+l++elm++n+y+li++rr+ lse+k+++++yq++++l+++h++g

Q: 64    LTLHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIRHYMYQLCRSLDHMHRNG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kl+dfG++r+v+sk+Pyt+y+strwyraPe+ll++g+y+++

Q: 124   IFHRDVKPENILIK-QDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYK  182

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlw++Gcv++e+a+l+plfPGa+e+dqi+ki++v+GtP++k++++ +k+++a++++fp+

Q: 183   MDLWSAGCVFYEIASLQPLFPGANELDQISKIHDVIGTPAQKTLTK-FKQSRAMSFDFPF  241

         **********************************************.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs++++l++++s ++l+ll++++aydPder++a+qal +pyf

Q: 242   KKGSGIPQLTTTLSPQCLSLLHAMVAYDPDERIAAHQALLHPYF  285

         *******************************************9

Domain Sequence
(FASTA)

YKAIGKIGEG TFSEVMKMQS LRDGNYYACK QMKQHFESIE QVNNLREVQA LRRLNPHPNI 60

LTLHEVVFDR KSGSLALICE LMDMNIYELI RGRRHPLSEK KIRHYMYQLC RSLDHMHRNG 120

IFHRDVKPEN ILIKQDVLKL GDFGSCRSVY SKQPYTEYIS TRWYRAPECL LTDGFYTYKM 180

DLWSAGCVFY EIASLQPLFP GANELDQISK IHDVIGTPAQ KTLTKFKQSR AMSFDFPFKK 240

GSGIPQLTTT LSPQCLSLLH AMVAYDPDER IAAHQALLHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013