EKS-ICT-00372

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00372

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	271.7	7.8E-81	1	185	185

Status

Unreviewed

Ensembl Protein

ENSSTOP00000008109

UniProt Accession

I3MCU6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K5

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000009007	ENSSTOP00000008109	ENSSTOT00000009047

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

622

Protein Sequence
(FASTA)

MEQVPGGSLS ALLRSKWGPL KDNEQTIGFY TKQILEGLKY LHDNQIVHRD IKGDNVLINT 60

YSGVLKISDF GTSKRLAGIN PCTETFTGTL QYMAPEIIDK GPRGYGKAAD IWSLGCTIIE 120

MATGKPPFYE LGEPQAAMFK VGMFKVHPEI PESMSAEAKA FILKCFEPDP DKRACANDLL 180

VDEFLKVSSK KKKSQSKFSV LSAGSNEYLR SISLPVPVLV EDTSSSSEYG SVSPDTELKV 240

DPFSFKTRAK SCGEKDVKGI RTLFLGIPDE NFEDHSAPPS PEEKDSGFFM LRKDSERRAT 300

LHRILTEDQD KVVRNLMESL AQGPEEPKLK WEHITTLVTS LREFVRSTDR KIIATTLSKL 360

KLELDFDSHG ISQVQVVLFG FQDAVNKVLR NHNIKPHWMF ALDSIIRKAV QTAITTLVPE 420

LRPHFSLASE SDTADPEDLD VEDDHEEPPS NQTVRRAQAV IEDAVATSGG STLSSTVSHA 480

SQSAHRSLNV QLGRMKIETN SRLLEELVRK EKELQALLHR AIEEKDQEIK HLKLKSQPID 540

IPGLAVCHLN SPGTTTEDSE LTDWLRENGA DEDTISRFLA EDYTLVDVLY YVTRDDLKCL 600

RLRGGMLCTL WKAIIDFRDK HT 622

Nucleotide Sequence
(FASTA)

ATGGAGCAGG TCCCAGGAGG AAGTCTTTCT GCTCTCCTTC GTTCCAAATG GGGCCCATTA 60

AAAGACAATG AGCAAACAAT TGGCTTTTAT ACAAAGCAAA TATTGGAAGG ATTAAAATAC 120

CTCCACGACA ATCAGATAGT TCACCGGGAT ATAAAGGGTG ACAATGTATT GATTAATACC 180

TATAGTGGTG TTCTCAAGAT CTCTGACTTT GGGACATCAA AGAGGCTTGC TGGCATAAAC 240

CCATGCACTG AAACTTTTAC TGGTACCCTT CAGTACATGG CACCAGAAAT AATTGACAAA 300

GGACCACGAG GCTATGGAAA AGCAGCAGAC ATTTGGTCTT TGGGCTGCAC AATCATTGAA 360

ATGGCTACAG GAAAACCACC GTTTTATGAA CTAGGAGAGC CACAAGCAGC CATGTTCAAG 420

GTTGGGATGT TTAAAGTCCA CCCTGAGATC CCAGAGTCCA TGTCTGCAGA GGCTAAAGCA 480

TTCATATTGA AATGTTTTGA ACCAGACCCA GACAAGAGAG CCTGTGCTAA TGACTTGCTT 540

GTTGATGAGT TCTTAAAAGT TTCCAGCAAA AAGAAAAAGT CACAATCCAA GTTTTCAGTG 600

CTTTCCGCTG GATCAAATGA ATATCTCAGG AGTATATCCT TGCCAGTGCC TGTCCTGGTA 660

GAAGACACCA GCAGCAGCAG TGAGTACGGC TCTGTGTCCC CTGATACAGA GCTGAAGGTG 720

GACCCCTTCT CTTTCAAAAC CAGAGCCAAG TCCTGTGGAG AAAAAGATGT GAAGGGAATA 780

CGGACACTCT TTTTGGGCAT TCCAGATGAA AATTTTGAGG ATCACAGTGC CCCGCCTTCC 840

CCTGAAGAAA AAGATTCTGG GTTCTTTATG CTGAGGAAGG ACAGTGAAAG GCGGGCCACC 900

CTTCATAGGA TCCTGACAGA AGACCAGGAC AAAGTTGTGA GGAACTTAAT GGAATCTTTA 960

GCTCAGGGGC CTGAAGAACC TAAACTAAAA TGGGAACACA TCACAACCCT CGTCACAAGC 1020

CTCAGAGAGT TTGTGAGGTC CACTGACCGA AAAATCATAG CCACTACGCT GTCAAAGCTG 1080

AAATTAGAGC TGGATTTTGA CAGCCATGGC ATCAGCCAAG TGCAGGTGGT CCTCTTTGGA 1140

TTCCAAGATG CGGTCAATAA GGTTCTTCGA AATCATAACA TCAAGCCACA CTGGATGTTC 1200

GCCTTGGACA GCATTATCCG CAAAGCCGTA CAGACAGCGA TTACCACACT GGTTCCAGAA 1260

CTGAGGCCAC ATTTTAGCCT GGCATCTGAG AGTGATACTG CCGATCCAGA AGACCTGGAT 1320

GTAGAAGATG ACCATGAGGA ACCACCTTCA AATCAAACTG TCCGAAGAGC CCAGGCTGTC 1380

ATTGAAGATG CTGTGGCTAC CTCAGGGGGG AGCACACTCA GCTCCACTGT GTCCCACGCT 1440

TCCCAGAGCG CTCACCGATC ACTGAACGTG CAGCTTGGAA GGATGAAGAT AGAAACTAAC 1500

AGCAGATTAC TGGAAGAATT GGTTCGGAAA GAGAAAGAAT TACAAGCACT CCTTCATCGA 1560

GCAATTGAAG AAAAAGATCA AGAAATCAAA CACCTGAAGC TAAAGTCCCA ACCAATAGAT 1620

ATTCCTGGGT TGGCTGTGTG TCACCTGAAC TCTCCTGGCA CAACCACTGA AGATTCTGAG 1680

CTTACTGACT GGCTGAGAGA AAATGGAGCT GATGAGGACA CTATAAGTCG GTTTCTGGCT 1740

GAGGATTATA CACTCGTGGA TGTCCTCTAC TATGTTACGC GCGATGATTT AAAATGCCTC 1800

AGACTAAGGG GAGGTATGCT GTGCACACTG TGGAAGGCGA TCATCGATTT TCGAGACAAA 1860

CACACTTAA 1869

Domain Profile

S: 80    lEyvegGslsslle.kygkle..esvikkytkqileglayLHekkivHRDiKgaNillds  136

         +E+v+gGsls+ll+ k+g+l+  e++i +ytkqilegl+yLH+++ivHRDiKg+N+l+++

Q: 1     MEQVPGGSLSALLRsKWGPLKdnEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINT  60

         9*************9*****9999************************************

S: 137   .sgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikkkekgygrkaDiWslgcv  195

          sgv+k+sDFG+skrla +n++   +e++tGtl+ymaPE+i+k+ +gyg++aDiWslgc+

Q: 61    ySGVLKISDFGTSKRLAGINPC---TETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT  117

         **********************...8**********************************

S: 196   viemltgkrPfaeldeelaimfkvgakktkPeipeklseegkdflekcleldpkkrpsae  255

         +iem+tgk+Pf el+e++a+mfkvg+ k++Peipe++s+e+k+f+ kc+e dp+kr++a+

Q: 118   IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN  177

         ************************************************************

S: 256   eLLkhefl  263

         +LL +efl

Q: 178   DLLVDEFL  185

         *****996

Domain Sequence
(FASTA)

MEQVPGGSLS ALLRSKWGPL KDNEQTIGFY TKQILEGLKY LHDNQIVHRD IKGDNVLINT 60

YSGVLKISDF GTSKRLAGIN PCTETFTGTL QYMAPEIIDK GPRGYGKAAD IWSLGCTIIE 120

MATGKPPFYE LGEPQAAMFK VGMFKVHPEI PESMSAEAKA FILKCFEPDP DKRACANDLL 180

VDEFL 185

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Callithrix jacchus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR013761	; SAM/pointed.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013