EKS-ICT-00272

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00272

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	481.8	5.4E-145	271	532	262

Status

Unreviewed

Ensembl Protein

ENSSTOP00000008139

UniProt Accession

I3MCW6;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1

Gene Synonyms/Alias

ERN1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000009067	ENSSTOP00000008139	ENSSTOT00000009079

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

677

Protein Sequence
(FASTA)

SWTHHAVSPQ PRGSTLPLLE GPQTDGVTIG DKGECVITPS TDLKFDPGLK GKNKLNYLRN 60

YWLLIGHHET PLSASTKMLE RFPNNLPKHR ENVIPADSEK KSFEDVINLV DQTENAPTTV 120

SQDVEEKLAR APAKPEAPVD SMLKDMATII LSTFLLVGWV AFIITYPLSM HQQQQLQNQQ 180

FQKELEKIQL LQQQQLPFHP PGELTQDVEL LDTSGPYSES SGTSSPSPSP RASNHSLHSG 240

SSVSKAGAGP FLEQDEEDEE TSMVIVGKIS FCPKDVLGHG AEGTIVYRGM FDNRDVAVKR 300

ILPECFSFAD REVQLLRESD EHPNVIRYFC TERDRQFQYI AIELCAATLQ EYVEQKDFAH 360

LGLEPITLLQ QTTSGLAHLH SLNIVHRDLK PHNILLSMPN AHGRIKAMIS DFGLCKKLAV 420

GRHSFSRRSG VPGTEGWIAP EMLSEDCKEN PTYTVDIFSA GCVFYYVISE GSHPFGKSLQ 480

RQANILLGAY SLECFHPEKH EDVIARELIE KMIAMDPQQR PSAKHVLKHP FFWSLEKQLQ 540

FFQDVSDRIE KESLDGPIVR QLERGGRAVV KMDWRENITV PLQTDLRKFR TYKGGSVRDL 600

LRAMRNKKHH YRELPVEVRE TLGSLPDDFV RYFTSRFPHL LSHTYRAMEL CSHERLFQPY 660

YFHEPLEPQP PVTPDAL 677

Nucleotide Sequence
(FASTA)

TCCTGGACTC ACCATGCCGT GTCTCCACAG CCTCGTGGCA GCACTCTTCC TTTGCTGGAA 60

GGCCCCCAGA CTGATGGTGT CACCATTGGG GACAAAGGGG AATGTGTGAT CACACCCAGC 120

ACAGACCTCA AGTTTGACCC CGGACTCAAA GGGAAGAACA AGCTCAACTA CTTGAGGAAT 180

TACTGGCTCC TGATAGGACA CCATGAAACC CCGCTGTCTG CATCTACCAA GATGCTGGAG 240

AGGTTTCCCA ACAATCTACC CAAACATCGG GAAAATGTGA TTCCTGCTGA TTCTGAGAAA 300

AAGAGTTTTG AAGACGTTAT CAACCTGGTG GATCAAACAG AAAATGCACC AACCACTGTG 360

TCTCAGGATG TGGAAGAGAA GTTGGCTCGT GCCCCTGCCA AGCCTGAGGC TCCTGTGGAC 420

TCCATGCTCA AGGACATGGC TACCATCATC CTAAGCACCT TCCTGCTGGT TGGCTGGGTA 480

GCCTTCATCA TCACCTACCC CCTGAGCATG CATCAGCAGC AGCAGCTCCA GAACCAGCAG 540

TTCCAAAAGG AACTGGAGAA AATCCAGCTC TTGCAGCAAC AGCAGCTGCC CTTCCATCCT 600

CCTGGAGAAT TGACCCAGGA CGTCGAGCTC CTGGACACAT CAGGCCCCTA CTCAGAGAGT 660

TCAGGCACCA GCAGCCCCAG CCCATCCCCC AGGGCTTCGA ACCACTCGCT GCACTCTGGC 720

AGCTCTGTCT CCAAGGCTGG TGCCGGCCCC TTCCTGGAGC AGGATGAGGA AGATGAGGAA 780

ACCAGCATGG TGATTGTTGG GAAAATTTCT TTCTGTCCCA AGGATGTCCT GGGCCATGGA 840

GCTGAGGGCA CAATTGTGTA CCGGGGCATG TTTGACAACC GTGATGTGGC CGTGAAGAGG 900

ATCCTCCCTG AGTGTTTTAG CTTCGCAGAC CGTGAGGTCC AGTTGTTGCG AGAATCAGAT 960

GAGCACCCGA ATGTCATCCG TTATTTCTGC ACGGAGAGGG ACCGGCAGTT CCAATATATT 1020

GCCATTGAGT TGTGTGCAGC CACCCTGCAG GAGTACGTAG AGCAGAAGGA CTTTGCCCAC 1080

CTTGGCCTAG AGCCCATCAC CTTGCTGCAG CAGACCACCT CAGGCCTGGC ACACCTCCAC 1140

TCCCTCAACA TTGTTCACAG AGATCTGAAG CCCCACAACA TTCTCCTCTC CATGCCCAAT 1200

GCACACGGCA GGATCAAGGC CATGATCTCT GACTTTGGCC TCTGTAAGAA GCTGGCGGTG 1260

GGCAGGCATA GCTTCAGTCG CCGTTCCGGG GTGCCTGGCA CTGAAGGCTG GATTGCCCCA 1320

GAGATGCTGA GTGAAGACTG CAAGGAGAAT CCTACCTATA CAGTGGACAT CTTCTCTGCA 1380

GGCTGCGTCT TTTACTACGT CATCTCTGAG GGCAGCCACC CCTTTGGCAA GTCCCTGCAG 1440

CGGCAGGCCA ACATCCTCTT GGGTGCCTAC AGCCTTGAGT GCTTCCACCC AGAGAAGCAT 1500

GAAGACGTCA TTGCACGTGA GCTGATAGAG AAAATGATCG CCATGGATCC CCAGCAGCGG 1560

CCCTCAGCGA AGCATGTTCT GAAACACCCA TTCTTCTGGA GCCTGGAAAA GCAGCTGCAG 1620

TTCTTTCAGG ACGTGAGTGA CCGAATAGAA AAGGAGTCCC TGGATGGCCC GATAGTGCGA 1680

CAGTTAGAAA GAGGCGGGAG AGCCGTGGTG AAGATGGACT GGCGGGAGAA CATCACTGTC 1740

CCCCTCCAGA CAGATCTGCG TAAATTCAGA ACCTACAAAG GTGGCTCCGT CAGAGATCTC 1800

CTTCGAGCCA TGAGAAATAA GAAACACCAC TACCGGGAGC TCCCAGTGGA GGTGCGGGAG 1860

ACGCTGGGCT CCCTTCCCGA TGACTTTGTG CGCTACTTCA CCTCCCGCTT CCCCCACCTC 1920

CTCTCACACA CCTACCGGGC CATGGAGCTG TGCAGCCACG AGAGACTCTT CCAGCCCTAC 1980

TACTTCCACG AGCCCCTGGA GCCCCAGCCC CCAGTGACTC CAGATGCCCT CTGA 2034

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+GaeGt+v+rG+f++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 271   FCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  330

         79**********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+drqf+yia+elcaa+lq+yve+kd++ + +lepi+ll+q++sGlahlhsl+ivhrdl

Q: 331   TERDRQFQYIAIELCAATLQEYVEQKDFA-HLGLEPITLLQQTTSGLAHLHSLNIVHRDL  389

         *****************************.******************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+a+g+++++isdfGlckkl+vG++sfsrrsgv+GteGwiape+l+e++ke

Q: 390   KPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKE  449

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t++vdifs+Gcvfyyv+s+G+hpfG+sl+rqanil g++sl+++++ek+e+via++li

Q: 450   NPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGAYSLECFHPEKHEDVIARELI  509

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         +kmi++dp++rpsak+vlkhp+f

Q: 510   EKMIAMDPQQRPSAKHVLKHPFF  532

         **********************9

Domain Sequence
(FASTA)

FCPKDVLGHG AEGTIVYRGM FDNRDVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TERDRQFQYI AIELCAATLQ EYVEQKDFAH LGLEPITLLQ QTTSGLAHLH SLNIVHRDLK 120

PHNILLSMPN AHGRIKAMIS DFGLCKKLAV GRHSFSRRSG VPGTEGWIAP EMLSEDCKEN 180

PTYTVDIFSA GCVFYYVISE GSHPFGKSLQ RQANILLGAY SLECFHPEKH EDVIARELIE 240

KMIAMDPQQR PSAKHVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00580

; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013