EKS-ICT-00195

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00195

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	513.0	1.9E-154	4	284	281

Status

Unreviewed

Ensembl Protein

ENSSTOP00000008569

UniProt Accession

I3MDR8;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000009548	ENSSTOP00000008569	ENSSTOT00000009553

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

574

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYTLRPLF PGTSEIDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASNEAIQL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GPSSHLLESK 300

QTLNKQLQSL ECKPAPADLD PKPLSDVTDQ TVGQPQPKHS HLPLQSIQPP QDGDLQQPPK 360

QQSQPRPPQT LFPSIVKNLP TKPNGPLAHK SARRRWGQTI LKAGDSWEEF EDCDFGASHS 420

KKPSMGVFKE KRKKDSPLRL SEAVPSGFHH STEENKSLPA AVHLKSDPQL SSASVAKQYY 480

LKQSRYLPGV NPKNVSFVAS GKNINPYAWN NHLFPKSLGP IGSEFAFKRS NAGNLGSYST 540

YNPSFLKKEV GSAGQRIHLA PLGATASGKS DSEV 574

Nucleotide Sequence
(FASTA)

ATGAACCGAT ACACGACCAT GAGACAGTTG GGGGACGGCA CCTACGGGAG TGTGCTGATG 60

GGCAAGAGTA ACGAGTCTGG GGAGCTGGTG GCCATCAAGA GGATGAAGAG AAAGTTCTAT 120

TCTTGGGACG AATGTATGAA CTTGAGAGAA GTGAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTGATTA AACTGAAAGA AGTTATCAGA GAAAATGACC ATCTTTATTT TATATTTGAA 240

TATATGAAAG AAAACCTCTA TCAATTAATG AAAGACAGAA ACAAATTGTT CCCTGAGTCA 300

GTCATCAGAA ATATTATGTA TCAGATATTG CAAGGGCTGG CGTTTATCCA TAAACATGGC 360

TTTTTCCATA GGGACATGAA ACCAGAAAAC TTGCTTTGCA TGGGCCCAGA ACTTGTGAAA 420

ATTGCTGATT TTGGACTTGC AAGAGAATTG AGGTCACAGC CACCATATAC TGATTATGTA 480

TCTACCAGAT GGTACCGTGC TCCTGAAGTT TTACTAAGAT CTTCAGTGTA CAGTTCTCCC 540

ATTGACGTGT GGGCTGTGGG AAGCATCATG GCCGAACTCT ATACCCTAAG ACCTCTGTTC 600

CCCGGGACAA GTGAAATTGA TGAAATCTTC AAAATCTGCC AAGTTTTAGG GACTCCCAAG 660

AAAAGTGACT GGCCAGAAGG ATACCAGCTT GCATCCTCTA TGAATTTCCG CTTTCCTCAG 720

TGTGTTCCTA TAAACTTAAA AACCCTTATT CCCAATGCCA GTAATGAAGC CATTCAGCTA 780

ATGACGGAAA TGTTGAATTG GGATCCAAAG AAACGACCAA CAGCAAGCCA GGCATTGAAA 840

CACCCATATT TTCAAGTTGG ACAGGTGTTA GGCCCTTCCT CACATCTTCT GGAATCAAAA 900

CAGACTTTAA ATAAGCAGCT GCAGTCATTA GAATGCAAGC CAGCTCCTGC TGACCTAGAC 960

CCCAAGCCTC TGTCAGACGT AACCGACCAG ACTGTCGGAC AGCCCCAGCC AAAGCACAGC 1020

CACCTACCAC TGCAGTCCAT TCAGCCGCCA CAGGACGGGG ACCTCCAGCA GCCTCCAAAG 1080

CAACAGAGTC AACCGAGACC GCCACAAACA CTGTTTCCTA GCATCGTCAA AAACCTGCCA 1140

ACTAAGCCAA ATGGTCCACT GGCTCATAAA AGTGCTAGAA GGCGTTGGGG TCAGACTATC 1200

CTCAAGGCTG GAGACAGCTG GGAAGAGTTT GAGGACTGTG ATTTTGGAGC CTCCCATTCC 1260

AAGAAGCCAA GCATGGGTGT TTTCAAAGAA AAGAGGAAAA AAGATTCTCC ACTTCGGCTC 1320

TCAGAGGCAG TACCCTCAGG CTTCCACCAC TCCACAGAGG AAAACAAGAG CTTACCTGCT 1380

GCCGTCCACC TAAAGTCTGA CCCCCAGCTG TCATCTGCAT CAGTGGCTAA ACAGTACTAC 1440

TTGAAACAAT CAAGATACCT TCCAGGTGTG AATCCCAAGA ATGTATCCTT CGTAGCTAGT 1500

GGAAAGAATA TAAACCCATA TGCTTGGAAT AATCACCTAT TTCCTAAGTC TCTGGGACCC 1560

ATTGGCAGTG AATTTGCTTT CAAAAGGAGT AATGCAGGAA ATCTTGGAAG TTACAGTACT 1620

TACAATCCTT CCTTTCTCAA AAAAGAAGTG GGGTCGGCTG GCCAGAGGAT CCACTTAGCA 1680

CCTCTCGGTG CCACAGCCTC AGGTAAGAGT GACTCAGAGG TG 1722

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+++e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+seid+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYTLRPLFPGTSEIDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++l++++l++dP++r+ta+qalk+pyf

Q: 241   CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFIFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YTLRPLFPGT SEIDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SNEAIQLMTE MLNWDPKKRP TASQALKHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013