EKS-ICT-00407

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00407

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	529.2	2.0E-159	35	292	258

Status

Unreviewed

Ensembl Protein

ENSSTOP00000009090

UniProt Accession

I3MEW3;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000010133	ENSSTOP00000009090	ENSSTOT00000010133

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

MASSPDGMPS PQPSRANGNI NLGPSANPNA RPTDFDFLKV IGKGNYGKVL LAKRKSDGMF 60

YAVKVLQKKS ILKNKEQSHI MAERNVLLKN VRHPFLVGLR YSFQTPEKLY FVLDYVNGGE 120

LFFHLQRERR FLEPRARFYT AEVASAIGYL HSLNIIYRDL KPENILLDCE GHVVLTDFGL 180

CKEGVEPEDT TSTFCGTPEY LAPEVLRKEP YDRAVDWWCL GAVLYEMLHG LPPFYSQDVS 240

QMYENILHQP LQIPGGRTVA ACDLLQGLLH KDQRQRLGSK ADFLEIKNHV FFSPINWDDL 300

YHKRLTPPFN PNVAGPADLK HFDPEFTQEA VSKSIGCTPD TMASSSGASS AFLGFSYAPE 360

DDDFLDC 367

Nucleotide Sequence
(FASTA)

ATGGCCTCTA GCCCTGACGG GATGCCTAGC CCACAGCCCT CCAGAGCCAA TGGGAACATC 60

AACCTGGGAC CTTCGGCCAA CCCAAATGCC AGGCCCACAG ACTTCGACTT CCTCAAAGTC 120

ATTGGCAAGG GGAACTATGG GAAGGTCCTA CTAGCCAAGC GCAAGTCCGA CGGGATGTTC 180

TACGCAGTGA AGGTGCTGCA GAAAAAATCC ATCTTAAAGA ATAAAGAGCA GAGCCACATC 240

ATGGCGGAAC GCAATGTGCT GCTGAAGAAC GTGCGGCACC CCTTCCTCGT GGGCCTGCGC 300

TATTCTTTCC AGACGCCCGA GAAGCTCTAC TTTGTACTCG ACTATGTCAA TGGAGGAGAG 360

CTCTTCTTCC ACCTGCAGCG GGAGCGTAGG TTCCTGGAGC CCCGGGCCAG ATTCTATACT 420

GCTGAAGTGG CCAGCGCCAT TGGCTACCTG CACTCCCTCA ACATCATTTA CAGGGACCTA 480

AAACCGGAGA ACATTCTCTT GGACTGCGAG GGACACGTGG TGCTGACGGA CTTCGGCCTT 540

TGTAAGGAAG GTGTGGAGCC CGAGGACACC ACATCCACAT TCTGTGGCAC CCCCGAGTAC 600

TTGGCTCCTG AAGTGCTTCG TAAGGAGCCT TACGATCGGG CGGTGGACTG GTGGTGCTTA 660

GGAGCAGTCC TCTACGAGAT GCTACATGGC CTGCCACCCT TCTACAGCCA AGACGTGTCC 720

CAGATGTATG AGAACATTCT GCACCAGCCA CTCCAGATTC CCGGAGGCCG GACAGTGGCT 780

GCCTGCGACC TCCTGCAAGG CCTTCTCCAC AAAGACCAGA GGCAGAGGCT GGGCTCCAAG 840

GCAGACTTTC TGGAGATAAA GAACCATGTA TTCTTCAGTC CCATAAACTG GGATGACTTG 900

TACCACAAGA GACTGACGCC GCCCTTCAAC CCAAATGTGG CAGGACCTGC TGACTTGAAA 960

CACTTTGACC CAGAGTTCAC CCAAGAAGCA GTCTCCAAGT CTATTGGCTG CACCCCTGAT 1020

ACTATGGCTA GCAGCTCAGG GGCCTCAAGT GCATTCCTGG GATTTTCCTA TGCCCCTGAG 1080

GATGATGACT TCTTGGACTG CTAG 1104

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkg++gkvllakrk+d+ fyavkvlqkk+ilk+ke++himaernvllknv+hp

Q: 35    FDFLKVIGKGNYGKVLLAKRKSDGMFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHP  94

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqrer+fleprarfy+ae+asa+gylhsln

Q: 95    FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLN  154

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++ghvvltdfglcke++e edttstfcgtpeylapevlrk+pydr+

Q: 155   IIYRDLKPENILLDCEGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRA  214

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml+glppfys+dv++my+nil++plq+++g++vaa++ll++ll+kd++

Q: 215   VDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQR  274

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg+k+dfleiknhvff

Q: 275   QRLGSKADFLEIKNHVFF  292

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG NYGKVLLAKR KSDGMFYAVK VLQKKSILKN KEQSHIMAER NVLLKNVRHP 60

FLVGLRYSFQ TPEKLYFVLD YVNGGELFFH LQRERRFLEP RARFYTAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCEGHVV LTDFGLCKEG VEPEDTTSTF CGTPEYLAPE VLRKEPYDRA 180

VDWWCLGAVL YEMLHGLPPF YSQDVSQMYE NILHQPLQIP GGRTVAACDL LQGLLHKDQR 240

QRLGSKADFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013