EKS-ICT-00232

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00232

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	342.0	1.8E-102	16	268	253

Status

Unreviewed

Ensembl Protein

ENSSTOP00000009268

UniProt Accession

I3MFA4;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA2

Gene Synonyms/Alias

PRKAA2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000010330	ENSSTOP00000009268	ENSSTOT00000010329

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KIGEHQLTGH KVAVKILNRQ KIRSLDVVGK 60

IKREIQNLKL FRHPHIIKLY QVISTPTDFF MVMEYVSGGE LFDYICKHGR VEEMEARRLF 120

QQILSAVDYC HRHMVVHRDL KPENVLLDAH MNAKIADFGL SNMMSDGEFL RTSCGSPNYA 180

APEVISGRLY AGPEVDIWSC GVILYALLCG TLPFDDEHVP TLFKKIRGGV FYIPEYLNRS 240

VATLLMHMLQ VDPLKRATIK DIREHEWFKQ DLPNYLFPED PSYDANVIDD EAVKEVCEKF 300

ECTESEVMNS LYSGDPQDQL AVAYHLIIDN RRIMNQASEF YLASSPPTGS FMDDSAMHIP 360

PGLKPHPERM PPLIADSPKA RCPLDALNTT KPKSLAVKKA KWHLGIRSQS KPYDIMAEVY 420

RAMKQLDFEW KVVNAYHLRV RRKNPVTGNY VKMSLQLYLV DNRSYLLDFK SIDDEVVEQR 480

SGSSTPQRSC SAAGLHRPRS SFDSTTIESH SLSGSLTGSL TGSTLSSVSP RLGSHTMDFF 540

EMCASLITTL AR 552

Nucleotide Sequence
(FASTA)

ATGGCTGAGA AGCAGAAGCA CGACGGGCGG GTGAAGATCG GGCACTACGT GCTGGGGGAC 60

ACGCTGGGCG TCGGCACCTT CGGCAAAGTG AAGATTGGAG AACATCAATT GACAGGCCAT 120

AAAGTGGCTG TTAAAATCTT AAATAGACAG AAGATTCGCA GTTTAGATGT TGTTGGAAAA 180

ATAAAACGAG AAATTCAAAA TCTAAAACTC TTCCGTCATC CTCATATTAT CAAACTATAC 240

CAGGTGATCA GCACTCCAAC AGATTTTTTT ATGGTAATGG AATATGTGTC TGGAGGTGAA 300

TTATTTGATT ACATCTGTAA ACATGGTCGG GTTGAAGAGA TGGAAGCTAG GCGGCTGTTT 360

CAGCAGATTC TGTCGGCGGT GGATTATTGT CACAGGCATA TGGTTGTTCA TCGAGACCTG 420

AAACCAGAGA ATGTGCTATT GGATGCACAT ATGAACGCCA AGATAGCTGA TTTTGGATTA 480

TCCAACATGA TGTCAGATGG TGAATTTCTA CGAACTAGTT GTGGATCTCC AAATTATGCA 540

GCACCTGAAG TCATCTCAGG CAGATTGTAT GCAGGTCCTG AAGTTGATAT CTGGAGCTGT 600

GGTGTTATCT TGTATGCTCT TCTTTGTGGC ACCCTCCCAT TTGATGATGA GCATGTACCT 660

ACATTGTTTA AGAAGATCCG AGGGGGTGTG TTTTATATTC CAGAGTATCT TAATCGTTCT 720

GTTGCTACTC TGCTGATGCA CATGCTGCAG GTTGACCCCC TGAAACGAGC AACTATCAAA 780

GACATAAGAG AGCATGAATG GTTTAAACAA GATTTGCCCA ATTACTTATT TCCTGAAGAC 840

CCCTCTTATG ATGCTAACGT TATTGATGAT GAGGCTGTGA AAGAAGTATG TGAAAAATTT 900

GAGTGTACAG AATCAGAAGT AATGAACAGT TTATATAGTG GTGACCCTCA AGACCAGCTT 960

GCAGTGGCAT ATCATCTTAT CATTGACAAT CGGAGAATAA TGAACCAAGC CAGTGAGTTC 1020

TACCTCGCCT CTAGCCCTCC AACTGGTTCT TTTATGGATG ATAGTGCCAT GCATATTCCC 1080

CCAGGCCTGA AACCTCATCC AGAAAGAATG CCACCTCTTA TAGCAGACAG TCCCAAAGCA 1140

AGATGTCCAT TGGATGCACT GAATACGACT AAGCCCAAGT CTTTAGCTGT GAAAAAAGCT 1200

AAGTGGCATC TTGGAATCAG AAGCCAGAGC AAACCATATG ACATTATGGC TGAAGTTTAC 1260

CGGGCTATGA AGCAGCTGGA TTTTGAATGG AAGGTAGTGA ATGCATACCA TCTTCGTGTA 1320

AGAAGAAAAA ATCCAGTGAC TGGCAATTAT GTGAAAATGA GCTTACAGCT TTACCTGGTT 1380

GATAATAGGA GCTATCTTTT GGACTTTAAA AGCATTGATG ATGAGGTGGT GGAGCAGAGA 1440

TCTGGTTCCT CAACACCTCA GCGTTCCTGT TCTGCTGCTG GCTTACACAG ACCAAGATCC 1500

AGCTTTGATT CTACGACTAT AGAAAGCCAT TCACTTTCTG GCTCTCTCAC TGGCTCTTTG 1560

ACCGGAAGCA CATTGTCTTC AGTTTCCCCT CGCCTGGGCA GTCATACCAT GGATTTTTTT 1620

GAAATGTGTG CCAGTCTGAT CACTACTTTA GCCCGTTGA 1659

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk  +h++t++kvavKi++++k+ s + + kikrEi+ lk ++hp+

Q: 16    YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIrSLDVVGKIKREIQNLKLFRHPH  75

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++gr++e ear+lf+q++sav+Y+h++ +

Q: 76    IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV  135

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 136   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  195

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws+Gv+Lyal++g+lPfd+e++ +l++ki  g + ip++l++++++Ll ++L+vdp k

Q: 196   DIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLK  255

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++hew+

Q: 256   RATIKDIREHEWF  268

         ************7

Domain Sequence
(FASTA)

YVLGDTLGVG TFGKVKIGEH QLTGHKVAVK ILNRQKIRSL DVVGKIKREI QNLKLFRHPH 60

IIKLYQVIST PTDFFMVMEY VSGGELFDYI CKHGRVEEME ARRLFQQILS AVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSCGVILY ALLCGTLPFD DEHVPTLFKK IRGGVFYIPE YLNRSVATLL MHMLQVDPLK 240

RATIKDIREH EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013