EKS-ICT-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RAD53	435.0	8.9E-131	1	265	265

Status

Unreviewed

Ensembl Protein

ENSSTOP00000010390

UniProt Accession

I3MHL4;

Protein Name

Protein Synonyms/Alias

Gene Name

CHEK2

Gene Synonyms/Alias

CHEK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000011573	ENSSTOP00000010390	ENSSTOT00000011576

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

322

Protein Sequence
(FASTA)

MSKTLGSGAC GEVKLAFERK TCKKVAIKII SKRKFAIGSS READPALNVE TEIEILKKLN 60

HPCIIKIKNF FDAEDYYIVL ELMEGGELFD RVVGNKRLKE ATCKLYFYQM LLAVQYLHEN 120

GIIHRDLKPE NVLLSSQEED CLIKITDFGQ SKILGETSLM RTLCGTPTYL APEVLLSIGT 180

AGYNRAVDCW SLGVILFICL SGYPPFSEHK TQVSLKDQIT SGKYNFIPEV WADVSEKALD 240

LVKKLLVVDP KARFTTEEAL SHPWLQDEDM KRKFQELLAE ENKSIALSQI PTQPSTSQKR 300

PLEGEAEDTE SSKRRAVCMA ML 322

Nucleotide Sequence
(FASTA)

ATGTCAAAAA CTCTTGGAAG TGGTGCTTGT GGAGAGGTAA AACTGGCTTT TGAGAGGAAA 60

ACATGTAAGA AAGTCGCCAT AAAGATCATC AGCAAAAGGA AATTTGCTAT TGGCTCTTCG 120

AGAGAGGCAG ATCCAGCTCT CAATGTTGAA ACTGAAATAG AAATCTTGAA AAAACTAAAT 180

CATCCTTGCA TCATCAAGAT TAAAAACTTT TTTGATGCAG AAGATTATTA CATTGTTTTG 240

GAATTGATGG AAGGAGGAGA GCTCTTTGAC AGGGTGGTGG GGAATAAACG GCTGAAAGAA 300

GCTACCTGCA AACTCTATTT TTACCAGATG CTCTTGGCTG TACAGTACCT TCACGAAAAT 360

GGCATTATAC ATCGGGATTT AAAGCCAGAG AATGTTCTAC TGTCATCTCA AGAAGAGGAC 420

TGTCTTATAA AGATTACTGA TTTTGGGCAG TCCAAGATTT TGGGGGAGAC CTCTCTCATG 480

AGAACTTTAT GTGGTACCCC CACTTACTTG GCTCCCGAGG TTCTTCTTTC CATTGGAACT 540

GCCGGGTATA ACCGTGCTGT GGACTGCTGG AGTTTAGGAG TTATTCTTTT TATCTGCCTT 600

AGTGGGTATC CACCTTTCTC TGAGCATAAG ACTCAAGTGT CACTGAAGGA TCAGATCACC 660

AGTGGAAAAT ACAACTTCAT TCCCGAAGTC TGGGCAGATG TTTCAGAGAA GGCTCTGGAT 720

CTCGTCAAGA AGTTGTTGGT TGTGGATCCA AAGGCACGGT TTACGACAGA AGAAGCCTTA 780

AGTCACCCGT GGCTTCAGGA TGAGGACATG AAGAGAAAGT TTCAGGAGCT ATTGGCCGAG 840

GAAAATAAAT CAATCGCTCT ATCCCAAATC CCAACCCAGC CTTCCACTAG TCAAAAGCGG 900

CCCCTGGAAG GGGAAGCCGA AGACACAGAG TCCTCAAAGC GCCGGGCTGT GTGTATGGCT 960

ATGCTGTGA 969

Domain Profile

S: 3     lskelGkGafgkvklayekktgkkvavkilskrk.sirssreikkakeveeeveilkkls  61

         +sk+lG+Ga+g+vkla+e+kt+kkva+ki+skrk +i+ssre++ a +ve+e+eilkkl+

Q: 1     MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKfAIGSSREADPALNVETEIEILKKLN  60

         699******************************999************************

S: 62    hPnivklkdvfeeeeskylvlelvegGelldkvvakkllkedlskllfkqlltavkylhe  121

         hP+i+k+k++f++e++ y+vlel+egGel+d+vv +k+lke+++kl+f+q+l av+ylhe

Q: 61    HPCIIKIKNFFDAEDY-YIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHE  119

         ***************9.*******************************************

S: 122   kgiihrDlkPeniLlsekeedvlvkitDfGlakvlgevslmktlCGtpsyvaPevlvkkg  181

         +giihrDlkPen+Lls++eed+l+kitDfG++k+lge+slm+tlCGtp+y+aPevl + g

Q: 120   NGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLLSIG  179

         ************************************************************

S: 182   raeytskvDiWslGvvlfvilsGypPfseeltqvslkeqilkgkyafieekwkkiseeak  241

         +a+y+++vD+WslGv+lf++lsGypPfse++tqvslk+qi++gky+fi+e+w+++se+a+

Q: 180   TAGYNRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWADVSEKAL  239

         ************************************************************

S: 242   dlikklLvvdPeerlsieealnhpWl  267

         dl+kklLvvdP++r+++eeal+hpWl

Q: 240   DLVKKLLVVDPKARFTTEEALSHPWL  265

         *************************8

Domain Sequence
(FASTA)

MSKTLGSGAC GEVKLAFERK TCKKVAIKII SKRKFAIGSS READPALNVE TEIEILKKLN 60

HPCIIKIKNF FDAEDYYIVL ELMEGGELFD RVVGNKRLKE ATCKLYFYQM LLAVQYLHEN 120

GIIHRDLKPE NVLLSSQEED CLIKITDFGQ SKILGETSLM RTLCGTPTYL APEVLLSIGT 180

AGYNRAVDCW SLGVILFICL SGYPPFSEHK TQVSLKDQIT SGKYNFIPEV WADVSEKALD 240

LVKKLLVVDP KARFTTEEAL SHPWL 265

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>