EKS-ICT-00220

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00220

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	426.7	3.1E-128	46	306	261

Status

Unreviewed

Ensembl Protein

ENSSTOP00000011084

UniProt Accession

I3MJ10;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000012366	ENSSTOP00000011084	ENSSTOT00000012368

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

384

Protein Sequence
(FASTA)

MDVETAEEQG APVPPPGALG GPGLGVAPAL GGRREPKKYA VTDDYQLSKQ VLGLGVNGKV 60

LECFHRRTGQ KCALKLLYDS PKARQEVDHH WQASGGPHIV CILDVYENMH HGKRCLLIVM 120

ECMEGGELFS RIQERGDQAF TEREAAGIMR DIGTAIQFLH SQNIAHRDVK PENLLYTSKE 180

KDAVLKLTDF GFAKETTQNA LQTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG 240

FPPFYSNTGQ AISPGMKRRI RLGQYGFPNP EWSEVSEDAK QLIRLLLKTD PTERLTITQF 300

MNHPWINQST VVPQTPLHTA RVLQEDKDHW DEVKEEMTSA LATMRVDYDQ VKIKDLKTSN 360

NRLLNKRRKK QAGSTSTSQG CNNQ 384

Nucleotide Sequence
(FASTA)

ATGGATGTCG AGACAGCAGA GGAGCAGGGG GCTCCTGTGC CCCCTCCAGG TGCACTCGGG 60

GGACCAGGCT TGGGGGTTGC TCCGGCCCTC GGGGGGCGGC GGGAGCCCAA GAAATACGCG 120

GTGACAGATG ACTACCAGTT ATCCAAGCAG GTGCTGGGCC TGGGTGTGAA CGGCAAGGTG 180

CTGGAGTGCT TCCACCGGCG CACTGGGCAG AAGTGTGCCC TGAAGCTCCT GTATGACAGC 240

CCCAAGGCCC GGCAGGAAGT GGACCACCAC TGGCAGGCCT CAGGTGGCCC CCACATTGTG 300

TGCATCCTGG ACGTGTATGA GAACATGCAT CACGGCAAAC GCTGTCTCCT CATTGTCATG 360

GAATGCATGG AAGGTGGTGA GTTATTCAGC AGGATTCAGG AGCGTGGTGA CCAGGCTTTT 420

ACTGAAAGAG AGGCTGCAGG GATAATGCGG GATATTGGCA CTGCTATCCA GTTCCTGCAT 480

AGCCAGAACA TTGCCCACAG AGATGTCAAG CCTGAAAACT TGCTCTATAC GTCCAAGGAG 540

AAAGATGCTG TGCTTAAGCT CACTGACTTC GGCTTTGCCA AGGAGACCAC CCAAAATGCC 600

CTGCAGACAC CCTGTTACAC TCCGTATTAT GTGGCCCCTG AGGTCCTGGG CCCAGAGAAG 660

TATGACAAGT CGTGTGACAT GTGGTCCCTG GGTGTCATCA TGTATATCCT CTTGTGTGGC 720

TTCCCACCCT TCTACTCCAA TACGGGCCAG GCCATCTCTC CAGGGATGAA GAGGAGGATT 780

CGCCTGGGCC AATATGGCTT CCCCAATCCT GAGTGGTCAG AGGTCTCTGA GGATGCCAAA 840

CAGCTGATCC GCCTGCTGCT GAAGACAGAC CCCACTGAGA GACTGACCAT CACACAGTTC 900

ATGAACCATC CTTGGATCAA TCAATCAACG GTGGTGCCAC AGACCCCACT CCACACAGCC 960

CGAGTGCTGC AGGAGGACAA AGACCACTGG GATGAAGTCA AGGAGGAGAT GACCAGTGCC 1020

CTGGCCACCA TGCGGGTGGA CTATGATCAG GTGAAGATCA AGGACCTGAA GACTTCTAAC 1080

AACCGGCTCC TCAACAAGCG GAGAAAAAAG CAGGCAGGCA GCACCTCGAC GTCACAGGGC 1140

TGCAACAACC AGTAG 1155

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         +l+++vlG G++gkvlec++++tg+k+alk+l+d++k+r+ev++h+qasg ++iv ++dv

Q: 46    QLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCILDV  105

         5789********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en+++++++ll+v+e++eGGel+sriqer  +afte+ea+ +++di++a++flhs+nia

Q: 106   YENMHHGKRCLLIVMECMEGGELFSRIQERgdQAFTEREAAGIMRDIGTAIQFLHSQNIA  165

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+skek+a++kl+Dfg+ake +++++l+tpc+t++yvaPevl++ek

Q: 166   HRDVKPENLLYTSKEKDAVLKLTDFGFAKE-TTQNALQTPCYTPYYVAPEVLGPEK----  220

         *****************************7.7899*********************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri+ g+y fP++eWsevse+a

Q: 221   -YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDA  279

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         k+lir lLk+dp+erlti++++nhpw+

Q: 280   KQLIRLLLKTDPTERLTITQFMNHPWI  306

         **************************8

Domain Sequence
(FASTA)

QLSKQVLGLG VNGKVLECFH RRTGQKCALK LLYDSPKARQ EVDHHWQASG GPHIVCILDV 60

YENMHHGKRC LLIVMECMEG GELFSRIQER GDQAFTEREA AGIMRDIGTA IQFLHSQNIA 120

HRDVKPENLL YTSKEKDAVL KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC 180

DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKRRIRLGQY GFPNPEWSEV SEDAKQLIRL 240

LLKTDPTERL TITQFMNHPW I 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013