EPS-ICT-00027

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ICT-00027

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.6	2.0E-56	232	485	254

Status

Unreviewed

Ensembl Protein

ENSSTOP00000011506

UniProt Accession

I3MJW4;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000012840	ENSSTOP00000011506	ENSSTOT00000012841

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

649

Protein Sequence
(FASTA)

MAGCSPEEKT YRRFLELFLG EFRGPCGGGE PEPEPESEPE PELVAAEAAE ASVEDPGEES 60

ATVNATEEGE PEQDPEPEEE AVEEEAEAVA AAEGEEEEEE EEEEAAPGHS AVQPPPQPQL 120

PPLPPLPRPL SERITREEVE GESLDLCLQQ LYKYNCPSFL AAALARATSD EVLQSDLSAH 180

YIPKETDGTE GSVEIETVKL ARSVFSKLHE ICCSWVKDFP LRRRPQLYYE TSIHAIKNMR 240

RKMEDKHVCI PDFNMLFNLE DQEEQAYFAV FDGHGGVDAA IYASIHLHVN LVRQEVFPHD 300

PAEALCRAFR VTDERFVQKA ARESLRCGTT GVVTFIRGNM LHVAWVGDSQ VMLVRKGQAV 360

ELMKPHKPDR EDEKQRIEAL GGCVVWFGAW RVNGSLSVSR AIGDAEHKPY ICGDADSAST 420

VLDGTEDYLI LACDGFYDTV NPDEAVKVVS DHLKENNGDS SMVAHKLVAS ARDAGSSDNI 480

TVIVVFLRDM NKAVNVSEES DWTENSFQGG QEDGGDDKEN HGECKRPWPQ HQCSAPADLG 540

YDGRVDSFTD RTSLSPGSQI NVLEDPGYLD LTQIEATKPH SAQILPSVEM FGLGAPKQAN 600

LINELIMKEK SVRSSLPERN GAGEFPGQQI YRMESLALVC SGLESEQFK 649

Nucleotide Sequence
(FASTA)

ATGGCCGGCT GCAGCCCAGA AGAGAAAACT TACCGGCGCT TCCTGGAGCT ATTCCTGGGC 60

GAGTTTCGTG GTCCTTGCGG CGGGGGCGAG CCAGAGCCTG AACCCGAGTC TGAGCCCGAA 120

CCTGAACTGG TAGCAGCTGA GGCGGCCGAA GCTTCGGTCG AGGATCCCGG GGAGGAGTCG 180

GCCACGGTAA ACGCAACGGA GGAGGGAGAA CCGGAGCAAG ACCCAGAGCC CGAAGAGGAG 240

GCGGTTGAGG AGGAGGCGGA GGCGGTGGCG GCGGCTGAGG GCGAGGAGGA GGAGGAGGAG 300

GAGGAGGAGG AGGCAGCCCC GGGGCACTCG GCCGTGCAAC CGCCGCCGCA GCCCCAGCTG 360

CCGCCGCTGC CCCCGCTCCC GCGACCGCTG TCGGAGCGCA TCACCCGTGA GGAGGTGGAG 420

GGCGAGAGCC TGGACCTGTG CCTGCAGCAG CTCTACAAAT ATAATTGCCC TTCATTTTTG 480

GCTGCTGCGT TAGCCAGAGC CACATCAGAT GAAGTGCTTC AAAGTGATCT TTCTGCACAT 540

TATATCCCAA AGGAAACGGA TGGCACAGAA GGGAGTGTGG AGATTGAGAC AGTGAAATTG 600

GCCCGTTCTG TCTTCAGCAA ACTACATGAG ATTTGCTGCA GCTGGGTGAA AGACTTCCCT 660

CTCCGCAGGA GACCCCAGCT TTACTATGAA ACATCAATCC ATGCCATCAA AAACATGCGC 720

AGGAAAATGG AGGACAAACA TGTCTGCATT CCTGACTTTA ATATGCTCTT CAACTTAGAG 780

GATCAGGAAG AACAAGCTTA CTTTGCAGTT TTTGATGGCC ATGGGGGAGT AGATGCTGCC 840

ATTTACGCTT CCATTCACCT ACATGTTAAT TTAGTACGCC AAGAGGTATT TCCCCATGAT 900

CCTGCTGAGG CTCTGTGCCG GGCCTTCCGG GTCACTGATG AGCGGTTTGT GCAGAAGGCA 960

GCTAGGGAGA GCTTAAGATG TGGGACCACA GGAGTGGTGA CTTTTATCAG AGGCAACATG 1020

CTACATGTGG CCTGGGTGGG TGATTCCCAG GTAATGCTTG TGAGAAAGGG CCAAGCTGTT 1080

GAACTAATGA AACCACACAA ACCAGACAGA GAGGATGAAA AACAGCGAAT TGAGGCCCTT 1140

GGAGGTTGTG TAGTCTGGTT TGGTGCCTGG AGGGTGAATG GAAGTCTGTC AGTCTCCAGA 1200

GCTATAGGAG ATGCTGAACA CAAGCCATAT ATCTGTGGGG ATGCAGATTC TGCCTCTACT 1260

GTTTTGGATG GGACAGAAGA CTACCTCATT CTGGCCTGTG ATGGCTTCTA TGATACTGTG 1320

AATCCTGATG AGGCAGTGAA AGTTGTGTCT GACCACCTGA AAGAGAACAA TGGAGACAGC 1380

AGTATGGTTG CCCACAAATT AGTGGCATCA GCTCGTGATG CTGGGTCAAG TGATAACATC 1440

ACTGTTATTG TGGTATTCCT GAGGGACATG AACAAAGCTG TAAATGTTAG TGAGGAATCA 1500

GATTGGACAG AGAACTCTTT TCAAGGAGGG CAAGAAGATG GTGGGGATGA TAAGGAGAAT 1560

CATGGAGAGT GCAAACGCCC TTGGCCTCAG CACCAGTGCT CAGCACCAGC CGATCTAGGC 1620

TATGATGGGC GTGTGGATTC ATTCACTGAT AGAACTAGCC TGAGCCCAGG GTCCCAAATC 1680

AACGTGCTGG AAGACCCAGG CTACCTAGAT CTCACACAAA TAGAAGCAAC CAAACCTCAC 1740

AGTGCCCAGA TTTTGCCATC AGTTGAGATG TTTGGTCTTG GTGCACCAAA GCAAGCAAAT 1800

CTTATTAATG AGCTAATAAT GAAGGAAAAA TCAGTTCGAT CATCATTGCC TGAACGGAAT 1860

GGTGCTGGAG AGTTTCCAGG GCAGCAGATA TACAGAATGG AGAGCTTGGC TCTTGTCTGT 1920

TCTGGGTTGG AAAGTGAACA GTTCAAA 1947

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++   p+f    + +d+   a+f+v+DGhgg ++a ++s +lh  l

Q: 232   SIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQeeQAYFAVFDGHGGVDAAIYASIHLHVNL  291

         567899**************99766555544459************************99

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++         +  +al +aF  tde++  ++++  ++ ++G+t vv  i+++ l+va

Q: 292   VRQEV----FPHDPAEALCRAFRVTDERF--VQKAARESLRCGTTGVVTFIRGNMLHVAW  345

         99966....6788888999**********..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         vGdS+++L r+g+avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 346   VGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  404

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  s+ l+  +++liLa+DG +d+v++ eav++v d+l+ ++ + + +a

Q: 405   AEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKeNNGDSSMVA  464

         ************************************************9966778899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 465   HKLVASARDAGSSDNITVIVV  485

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASIHLHVNL 60

VRQEVFPHDP AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWVGDSQV 120

MLVRKGQAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADSASTV LDGTEDYLIL ACDGFYDTVN PDEAVKVVSD HLKENNGDSS MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>