EKS-ICT-00198

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00198

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	516.4	1.4E-155	4	286	283

Status

Unreviewed

Ensembl Protein

ENSSTOP00000012102

UniProt Accession

I3ML50;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL4

Gene Synonyms/Alias

CDKL4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000013506	ENSSTOP00000012102	ENSSTOT00000013506

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

342

Protein Sequence
(FASTA)

MEKYEKLAKI GEGSYGVVFK CRNKSSGQVV AIKKFVESED DPVVKKIALR EIRLLKQLKH 60

SNLVNLIEVF RRKRKMHLVF EYCDHTLLNE LERNPNGVAD GVIKSVLWQT LQALNFCHKH 120

NCIHRDVKPE NILITKQGII KICDFGFARI LIPGDIYTDY VATRWYRAPE LLVGDTQYDC 180

SVDVWAVGCV FAELLTGQPL WPGKSDVDQL YLIIRTLGKL IPRHQSIFKN NQFFHGISIP 240

EPEDMETLEE KFSDAYPVAL NFMKGCLKMN PDDRLTCAQL LESSYFDSFQ EDQMKRKARN 300

EGRNRRRQQN QLLPLIPGSH ISPTPDGRKQ VLQLKFDHLP NI 342

Nucleotide Sequence
(FASTA)

ATGGAAAAGT ATGAAAAATT AGCTAAGATT GGAGAAGGGT CTTATGGAGT TGTGTTCAAG 60

TGCAGAAACA AATCCTCTGG ACAAGTAGTA GCTATTAAAA AATTCGTGGA ATCTGAAGAT 120

GACCCTGTTG TTAAGAAAAT AGCACTGAGA GAAATTCGCT TGTTGAAGCA ATTAAAACAT 180

TCAAACCTTG TGAACCTCAT TGAGGTGTTC AGGAGAAAAA GGAAAATGCA TTTAGTTTTT 240

GAATACTGTG ATCATACACT TTTAAATGAG CTGGAAAGAA ACCCAAATGG AGTTGCTGAT 300

GGAGTGATCA AAAGTGTATT ATGGCAAACA CTTCAAGCTC TTAATTTCTG TCATAAACAT 360

AATTGTATTC ACCGAGATGT AAAACCTGAA AACATTCTCA TAACCAAGCA AGGAATAATC 420

AAGATCTGTG ACTTTGGGTT TGCACGAATT CTGATTCCAG GAGACATCTA CACTGATTAT 480

GTTGCCACTC GGTGGTACAG GGCTCCTGAG CTTCTCGTGG GAGACACCCA ATACGATTGT 540

TCCGTCGATG TGTGGGCTGT TGGTTGCGTT TTTGCAGAGC TCCTGACTGG CCAGCCACTC 600

TGGCCTGGAA AATCAGATGT GGACCAGCTT TATCTGATAA TCAGAACACT GGGAAAACTA 660

ATTCCAAGAC ATCAGTCCAT CTTTAAAAAT AACCAGTTTT TCCATGGCAT CAGTATACCT 720

GAACCTGAAG ACATGGAAAC TCTTGAGGAA AAGTTCTCAG ATGCTTATCC TGTGGCTTTG 780

AATTTCATGA AGGGGTGTTT GAAGATGAAT CCAGATGACA GGTTAACCTG TGCCCAACTC 840

CTAGAGAGCT CCTACTTTGA TTCCTTTCAA GAGGATCAAA TGAAAAGAAA AGCACGTAAT 900

GAGGGAAGAA ACAGAAGGCG TCAGCAGAAT CAACTGTTGC CTCTCATACC AGGAAGCCAC 960

ATCTCCCCCA CACCTGATGG AAGAAAACAA GTCCTCCAGT TAAAATTTGA TCATCTTCCA 1020

AACATT 1026

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yekl+k+GeGsyGvv+kcrnk++gq+vaikkf+esedd++vkkialrei+llkqlkh nl

Q: 4     YEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDPVVKKIALREIRLLKQLKHSNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk+k++lvfey+d+t+l+eler+pnGv + ++k++l+q+l+a++fchk+n+i

Q: 64    VNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHKHNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k+g++k+cdfGfar+l+ pgd+ytdyvatrwyrapellvgdt+y  sv

Q: 124   HRDVKPENILITKQGIIKICDFGFARILI-PGDIYTDYVATRWYRAPELLVGDTQYDCSV  182

         *****************************.******************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwa+Gc++aelltG+pl+pgksdvdqly+i++tlG+liprhq+if++n++f+G+++pe+

Q: 183   DVWAVGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKNNQFFHGISIPEP  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ed+e+le+k++++ +v+l+++k+clk++p++rl+c++ll+++yf

Q: 243   EDMETLEEKFSDAYPVALNFMKGCLKMNPDDRLTCAQLLESSYF  286

         ******************************************98

Domain Sequence
(FASTA)

YEKLAKIGEG SYGVVFKCRN KSSGQVVAIK KFVESEDDPV VKKIALREIR LLKQLKHSNL 60

VNLIEVFRRK RKMHLVFEYC DHTLLNELER NPNGVADGVI KSVLWQTLQA LNFCHKHNCI 120

HRDVKPENIL ITKQGIIKIC DFGFARILIP GDIYTDYVAT RWYRAPELLV GDTQYDCSVD 180

VWAVGCVFAE LLTGQPLWPG KSDVDQLYLI IRTLGKLIPR HQSIFKNNQF FHGISIPEPE 240

DMETLEEKFS DAYPVALNFM KGCLKMNPDD RLTCAQLLES SYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013