EKS-ICT-00388

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00388

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	354.1	5.4E-106	210	486	277

Status

Unreviewed

Ensembl Protein

ENSSTOP00000012537

UniProt Accession

I3MM31;

Protein Name

Protein Synonyms/Alias

Gene Name

IRAK2

Gene Synonyms/Alias

IRAK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000013972	ENSSTOP00000012537	ENSSTOT00000013990

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

616

Protein Sequence
(FASTA)

MACYIYQLPA WVLDDLCRNM DTLSDWDWMQ FASKVIPDLT QLRKIKSMER VQGVSITREL 60

LWWWGMRQAT VQQLVDLLCR LELYRAAQIV LSWKPVPETR PSFPASPEVV KPGSEAAFGR 120

NTQDEQERGQ PLRPTAFPGP GSAPARDQHQ ASLPLSSKEV VLHSSRPHLP TSLDSKDFST 180

SVPQQEKCSN MTEENLFWSE AEVIQATGDF DQSHRISEGT FADVYRGQRH GMPLAFKKLR 240

ETACSSPGSV ERYFQAEVQL CLRCCHPNIL PLLGYCSGKQ FHSLIYPYMT NGSLQDRLQS 300

QGDLEPLPWP QRVSICSGLL CAVEHLHGLE IIHGNIKSSN VLLDQNFTPK LAHPMAHLCP 360

VNQRSKYTMM KTHLFQASAA YLPEDFIRVG QLTKRVDIFS CGIVLAEILT GIRAVDKDRS 420

PVYLKDLLLS EIPSSTSSFC SRKTGVEKAV AKEICQKYLE KRAGVLPEHC AEALGTAICL 480

CLRRRNASLE EAHGSVAVVE EWFRSQETSL PWSGFSEGTG ASSNTPEETD DVDDGSLDAP 540

SSVRASPVPA ENGEERLQDT RGVEADSSEA CTGPRSPENA TETSWEVEIN EAKRKLMENI 600

LLYNEEQLDS AELFGP 616

Nucleotide Sequence
(FASTA)

ATGGCCTGCT ACATCTACCA GCTGCCCGCC TGGGTGCTGG ACGACCTGTG TCGCAACATG 60

GACACGCTCA GCGACTGGGA CTGGATGCAG TTCGCCTCCA AAGTAATCCC AGACCTGACC 120

CAGCTGCGGA AGATCAAGTC CATGGAGCGG GTGCAGGGCG TGAGCATCAC CCGCGAGCTG 180

CTCTGGTGGT GGGGCATGCG GCAGGCTACC GTCCAGCAGC TGGTGGACCT CCTGTGTCGC 240

CTGGAGCTCT ACCGCGCTGC CCAGATCGTC CTGAGCTGGA AACCAGTTCC TGAAACCAGA 300

CCTTCTTTCC CAGCCTCCCC AGAGGTGGTG AAGCCAGGAT CTGAAGCAGC CTTTGGGAGA 360

AACACCCAGG ATGAGCAGGA AAGGGGGCAA CCCTTGAGGC CCACTGCCTT CCCAGGTCCA 420

GGGTCCGCTC CAGCCAGAGA CCAGCACCAG GCCTCTCTCC CGCTTTCTTC TAAGGAGGTT 480

GTGCTTCATT CCTCAAGACC TCACCTCCCC ACCTCACTGG ATTCAAAGGA CTTCAGTACC 540

TCCGTTCCAC AGCAAGAAAA GTGCTCAAAC ATGACTGAAG AAAACCTTTT CTGGAGTGAG 600

GCAGAAGTGA TCCAGGCAAC AGGTGACTTT GATCAAAGCC ACAGAATCAG CGAAGGCACC 660

TTTGCTGATG TCTACAGAGG GCAAAGGCAC GGGATGCCCT TAGCCTTCAA GAAGCTCAGA 720

GAGACAGCCT GCTCAAGTCC AGGGTCAGTG GAGAGGTACT TCCAGGCAGA GGTGCAGCTT 780

TGTCTTAGAT GTTGCCACCC CAACATCTTA CCTCTGCTGG GCTATTGCTC CGGAAAACAG 840

TTTCACAGTC TGATCTACCC CTACATGACA AATGGTTCTC TTCAGGACAG ACTCCAGAGT 900

CAGGGTGACT TGGAGCCCCT CCCCTGGCCC CAGCGTGTCA GCATCTGCTC AGGGCTGCTC 960

TGTGCTGTTG AGCACCTGCA TGGCCTGGAG ATTATCCATG GCAACATCAA GAGCTCCAAT 1020

GTTTTGCTGG ACCAAAATTT CACCCCCAAG CTGGCTCATC CAATGGCTCA CCTGTGTCCT 1080

GTCAACCAAA GGTCAAAATA CACCATGATG AAGACCCACC TTTTCCAGGC CTCCGCGGCG 1140

TACCTTCCAG AAGATTTCAT CAGGGTGGGG CAGCTGACAA AGCGAGTGGA CATCTTCAGC 1200

TGTGGAATAG TGCTGGCAGA GATCCTCACT GGCATCCGTG CAGTGGATAA GGACCGAAGC 1260

CCAGTTTATC TGAAGGATCT ACTCCTCAGT GAGATTCCCA GCAGCACCTC CTCATTCTGC 1320

TCCAGGAAGA CGGGTGTGGA GAAGGCAGTG GCAAAGGAGA TCTGCCAGAA GTACCTGGAA 1380

AAAAGAGCAG GGGTGCTGCC AGAGCACTGT GCTGAGGCCT TGGGCACAGC CATCTGCCTC 1440

TGCCTGCGGA GGCGCAATGC CAGCCTGGAG GAGGCGCATG GCTCTGTGGC TGTGGTGGAG 1500

GAGTGGTTCC GAAGTCAGGA GACCTCGCTG CCTTGGAGCG GGTTCTCTGA GGGCACAGGA 1560

GCTTCCTCCA ACACTCCTGA GGAAACAGAT GATGTGGACG ATGGTAGCCT TGATGCCCCC 1620

TCCTCTGTGA GGGCCTCACC TGTCCCTGCA GAGAACGGAG AAGAAAGGCT ACAGGACACC 1680

AGAGGAGTGG AGGCAGACTC CTCTGAGGCC TGCACTGGCC CACGGTCTCC CGAGAATGCT 1740

ACAGAGACTT CATGGGAAGT TGAGATCAAT GAGGCCAAAC GGAAACTGAT GGAGAACATC 1800

CTGCTCTACA ATGAGGAACA ACTAGACAGT GCTGAGCTCT TTGGACCTTG A 1851

Domain Profile

S: 1     fsednrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdni  60

         f++++ri+eG+f++vyrg+++++ +a+kkl+e+a++s+ ++++ f++E+++++r++H+ni

Q: 210   FDQSHRISEGTFADVYRGQRHGMPLAFKKLRETACSSPGSVERYFQAEVQLCLRCCHPNI  269

         789*********************************************************

S: 61    lellgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtaraiefLHea  120

         l+llgy++ +++++L+Y+ym+nGsL+drLq q++ epL+WpqR+si++G+++a+e+LH

Q: 270   LPLLGYCSGKQFHSLIYPYMTNGSLQDRLQSQGDLEPLPWPQRVSICSGLLCAVEHLHGL  329

         ************************************************************

S: 121   spslihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlpeef  180

           ++ihg+iks+N+LLD+++tpKl+ +++a+++p ++++++t+++t+ +++++aYlpe+f

Q: 330   --EIIHGNIKSSNVLLDQNFTPKLA-HPMAHLCPVNQRSKYTMMKTHLFQASAAYLPEDF  386

         ..***********************.**********************************

S: 181   irvgqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekv.........  231

         irvgqlt++vD++S+GiVl+E+ltG+ravd+dr+++yLkdll +ei++++

Q: 387   IRVGQLTKRVDIFSCGIVLAEILTGIRAVDKDRSPVYLKDLLLSEIPSSTSsfcsrktgv  446

         **************************************************9*********

S: 232   ......eilekfldkkagkleeellealielalaclaeka  265

               ei++k+l+k+ag l+e+++eal ++ + cl +++

Q: 447   ekavakEICQKYLEKRAGVLPEHCAEALGTAICLCLRRRN  486

         ***********************************99765

Domain Sequence
(FASTA)

FDQSHRISEG TFADVYRGQR HGMPLAFKKL RETACSSPGS VERYFQAEVQ LCLRCCHPNI 60

LPLLGYCSGK QFHSLIYPYM TNGSLQDRLQ SQGDLEPLPW PQRVSICSGL LCAVEHLHGL 120

EIIHGNIKSS NVLLDQNFTP KLAHPMAHLC PVNQRSKYTM MKTHLFQASA AYLPEDFIRV 180

GQLTKRVDIF SCGIVLAEIL TGIRAVDKDR SPVYLKDLLL SEIPSSTSSF CSRKTGVEKA 240

VAKEICQKYL EKRAGVLPEH CAEALGTAIC LCLRRRN 277

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>