EKS-ICT-00087

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00087

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	407.1	6.1E-122	2093	2417	325

Status

Unreviewed

Ensembl Protein

ENSSTOP00000012906

UniProt Accession

I3MMW0;

Protein Name

Protein Synonyms/Alias

Gene Name

SMG1

Gene Synonyms/Alias

SMG1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000014364	ENSSTOP00000012906	ENSSTOT00000014408

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

3631

Protein Sequence
(FASTA)

RTDSASADPD NLKYSSARDR GGSSSYGLQP SNSAVVSRQR HDDTRVHADI QNDEKGGYSV 60

NGGSGENTYG RKSLGQELRV NNVTSPEFTS VQHGSRALAT KDMRKSQERS MSYSDESRLS 120

NLLRRITRED DRDRRLATVK QLKEFIQQPE NKLVLVKQLD NILAAVHDVL NESSKLLQEL 180

RQEGACCLGL LCASLSYEAE KIFKWIFSKF SSSAKDEVKL LYLCATYKAL ETVGEKKAFS 240

SVMQLVMTSL QSILENVDTP ELLCKCVKCI LLVARCYPHI FSTNFRDTVD ILVGWHIDHT 300

QKPSLTQQVS GWLQSLEPFW VADLAFSTTL LGQFLEDMEA YAEDLSHVAS GESVDEDVPP 360

PSVSLPKLAA LLRVFSTVVR SIGERFSPIR GPPITEAYVT DVLYRVMRCV TAANQVFFSE 420

AVLTAANECV GVLLGSLDPS MTIHCDMVIT YGLDQLENCQ TCGTDYIISV LNLLTLIVEQ 480

INTKLPSSFV EKLFIPSSKL LFLRYHKEKE VVAVAHAVYQ AVLSLKNIPV LETAYKLILG 540

EMTCALNNLL HSLQLPDACS EIKHEAFKNH VFNVDNAKFV VIFDLSALTT IGNAKNSLIG 600

MWALSPTVFA LLSKNLMIVH SDLAVHFPAI QYAVLYTLYS HCTRHDHFIS SSLSSSSPSL 660

FDGAVISTVT TATKKHFSII LNLLGILLKK DNLNQDTRKL LMTWALEVAV LMKKSETYAP 720

LFSLPSFHKF SKGLLANTLV EDVNICLQAC SSLHALSSSL PDDLLQRCVD VCRVQLVHSG 780

TRIRQAFGKL LKSIPLDVVL SNNNHTEIQE ISLALRSHMS KAPSNTFHPQ DFSDVISFIL 840

YGNSHRTGKD NWLERLFYSC QRLDKRDQST IPRNLLKTDA VLWQWAIWEA AQFTVLSKLR 900

TPLGRAQDTF QTIEGIIRSL AAHTLNPDQD VSQWTTADND EGHSSNQLRL VLLLQYLENL 960

EKLMYNAYEG CANALTSPPK VIRTFFYTNR QTCQDWLTRI RLSIMRVGLL AGQPAVTVRH 1020

GFDLLTEMKT NSLSQGNELE VTIMMVVEAL CELHCPEAIQ GIAVWSSSIV GKNLLWINSV 1080

AQQAEGRFEK ASVEYQEHLC AMTGVDCCIS SFDKSVLTLA NVGRNSASPK HSLNGESRKT 1140

VLSKPTDSSP EVINYLGNKA CECYISIADW AAVQEWQNAI HDLKKSTSST SLNLKADFNY 1200

IKSLSSFESG EFVECTEQLE LLPGENINLL AGGSKEKIDM KKLLPNMLSP DPRELQKSIE 1260

VQLLRSSVCL ATALNHIEQD QKWQSITENV VKYLKQTSRI AIGPLRLSTL TVSQSLPVLS 1320

TLQLYCSSAL ENTVSNRLST EDCLIPLFSE ALRSCKQHDV RPWMQALRYT MYQNQLLEKI 1380

KEQTVPIRSH LMELGLTAAK FARKRGNVSL ATRLLAQCSE VQLGKTTTAQ DLVQHFKKLS 1440

TQGQVDEKWG PELDIEKTKL LYTAGQSTHA MEMLSSCAIS FCKSAKAEYA VAKSILTLAK 1500

WIQAEWKEIS GQLKQVYRAQ QQQSFSGLST LSKNILTLIE LPSVNTVEEE YPRIESESTV 1560

HIGVGEPDFI LGQLYHLSSV QAPEVAKSWA ALASWAYRWG RKVVDNASQG EGVRLLPREK 1620

SEVQNLLPDT ITEEEKERIY GILGQAVCRP AGIQDEDITL QITENEDNEE DDMVDVIWRQ 1680

LISSCPWLSE LDESATEGVI KVWRKVVDRI FSLYKLSCSA YFTFLKLNAG QIPLEEDDPR 1740

LHLSHRAEQS TDDVIVMATL RLLRLLVKHA GELRQYLEHG LETTPTAPWR GIIPQLFSRL 1800

NHPEVYVRQS ICNLLCRVAQ DSPHLILYPA IVGTISLSSE SQASGNKFSS AIPTLLGNIQ 1860

GEELLVSECE GGSPPTSQDS NKDEPKSGLN EDQAMMQDCY SKIVDKLSSA NPTMVLQVQM 1920

LVAELRRVTV LWDELWLGVL LQQHMYVLRR IQQLEDEVKR VQNNNTLRKE EKIAIMREKH 1980

TALMKPIVFA LEHVRSITAA PAETPHEKWF QDNYGDAIEN ALEKLKTPSN PAKPGSSWIP 2040

FKEIMLSLQQ RAQKRASYIL RLEEISPWLA AMTNTEIALP GEVSARDTVT IHSVGGTITI 2100

LPTKTKPKKL LFLGSDGKSY PYLFKGLEDL HLDERIMQFL SIVNTMFATI NRQETPRFHA 2160

RHYSVTPLGT RSGLIQWVDG ATPLFGLYKR WQQREAALQA QKAQDSYQTP QNPGIVPRPS 2220

ELYYSKIGPA LKTVGLSLDV SRRDWPLHVM KAVLEELMEA TPPNLLAKEL WSSCTTPDEW 2280

WRVTQSYARS TAVMSMVGYI IGLGDRHLDN VLIDMTTGEV VHIDYNVCFE KGKSLRVPEK 2340

VPFRMTQNIE TALGVTGVEG VFRLSCEQVL HIMRRGRETL LTLLEAFVYD PLVDWTAGGE 2400

AGFAGAVYGG GGQQAESKQS KREMEREITR SLFSSRVAEI KVNWFKNRDE MLVVLPKLDS 2460

SLDEYLSLQE QLTDVEKLQG KLLEEIEFLE GAEGVDHPSH TLQHRYSEHT QLQTQQRAVQ 2520

EAIQVKLNEF EQWITHYQAA FNNLEATQLA SLLQEISTQM DLGPPSYVPA TAFLQNAGQA 2580

HLISQCEQLE GEVGALLQQR RSVLRGCLEQ LHHYATVALQ YPKAIFQKHR IEQWKTWMEE 2640

LICNTTVERC QELYRKYEMQ YAPQPPPTVC QFITATEMTL QRYAADINSR LIRQVERLKQ 2700

EAVTVPVCED QLKEIERCIK VFLHENGEEG SLSLASVIIS ALCTLTRRNL MMEGAASSAG 2760

EQLVDLTSRD GAWFLEELCS MSGNVTCLVQ LLKQCHLVPQ DLDIPNPVEA SEAVHLANGV 2820

YTSLQELNSN FRQIIFPEAL RCLMKGEYTL ESMLHELDSL IEQTTDGVPL QTLVESLQAY 2880

LRNAAMGLEE ETHAHYIDVA RILHAQYGEL IQPRNGSVDE TPKMSAGQML LVAFDGMFAQ 2940

VETAFGLLVE KLNKMEIPVA WRKIDIIREA RSTQVNFFDD DNHRQVLEEI FFLKRLQTIK 3000

EFFRLCGTFS KTLSGSSSLE EQNTVNGPVQ IVNVKTLFRN SCFSEDQMAK PIKAFTADFV 3060

RQLLIGLPNQ ALGLTLCSFI SALGVDIIAQ VEAKDFGAES KVSVDDLCKK AVEHNIQVGK 3120

FSQLVMNRAT VLASSYDTAW KKHDLVRRLE TSISSCKTSL QRVQLHIAMF QWQHEDLLIN 3180

RPQAMSVTPP PRSAILTSMK KKLHTLSQIE TSIATVQEKL AALEASIEQR LKWAGGANPA 3240

LAPVLQDFEA TIAERRNLVL KESQRASQVT FLCSNIIHFE SLRTRTAEAL NLDAALFELI 3300

KRCQQMCSFA SQFNSSVSEL ELRLLQRVDT SLEHPIGSSE WFLSAHKQLT QDMSSQRAIQ 3360

TEKEQQIETV CETIQNLVDN IKTVLTGHNR QLGDVKHLLK AMAKDEEAAL ADGEDVPYEN 3420

SVRQFLSEYK SWQDNIQTVL FTLVQAMGQV RSQEHVEMLQ EITPTLKELK TQSQSIYNNL 3480

VSFASPLVTD ATNECSSPTS SATYQPSFAA AVRSNTGQKT QPDVMSQNAK KLIQKNLATS 3540

ADTPPSTVPG TGKSIACSPK KAVRDPKTGK AVQERNSYAV SVWKRVKAKL EGRDVDPNRR 3600

MSVAEQVDYV IKEATNLDNL AQLYEGWTAW V 3631

Nucleotide Sequence
(FASTA)

AGAACTGATA GTGCATCAGC CGACCCGGAT AATTTAAAAT ATTCTTCAGC CAGAGATAGG 60

GGTGGTTCTT CCTCTTATGG ACTGCAACCT TCAAATTCAG CTGTGGTGTC TCGGCAAAGG 120

CACGATGATA CCAGAGTCCA TGCTGACATA CAGAATGACG AAAAGGGTGG CTACAGTGTC 180

AATGGAGGAT CTGGGGAAAA TACTTATGGT CGGAAGTCGT TGGGGCAAGA GCTGAGAGTT 240

AACAATGTGA CCAGCCCTGA GTTCACCAGT GTTCAGCATG GCAGTCGTGC ATTAGCCACC 300

AAAGACATGA GGAAATCACA GGAGCGATCG ATGTCTTATT CTGATGAGTC TCGACTGTCG 360

AATCTTCTTC GGAGGATCAC CCGGGAAGAC GACAGAGACC GAAGACTGGC TACTGTAAAG 420

CAGTTGAAAG AATTTATTCA GCAGCCAGAA AATAAGCTGG TATTAGTGAA GCAATTGGAT 480

AATATCTTGG CTGCTGTACA TGATGTGCTT AATGAAAGTA GCAAATTGCT TCAGGAATTG 540

AGACAGGAGG GAGCTTGCTG TCTTGGCCTT CTTTGTGCTT CTTTAAGCTA TGAGGCTGAG 600

AAGATCTTCA AATGGATTTT TAGTAAATTT AGCTCATCTG CAAAAGATGA AGTTAAACTC 660

CTCTACTTAT GTGCCACCTA CAAAGCATTG GAGACTGTAG GAGAAAAGAA AGCCTTTTCA 720

TCTGTAATGC AGCTTGTAAT GACCAGCCTG CAGTCCATTC TTGAAAATGT GGATACACCA 780

GAATTACTTT GCAAATGTGT TAAGTGCATT CTTTTGGTGG CTCGATGTTA CCCTCATATT 840

TTCAGCACTA ATTTTAGGGA TACGGTTGAT ATATTAGTTG GATGGCACAT AGATCATACT 900

CAGAAACCTT CACTCACACA GCAGGTTTCT GGGTGGTTGC AGAGTTTGGA GCCATTTTGG 960

GTAGCTGATC TTGCATTTTC TACCACTCTT CTTGGTCAGT TTCTAGAAGA CATGGAGGCA 1020

TATGCTGAGG ATCTCAGCCA TGTGGCCTCT GGGGAATCAG TGGATGAAGA CGTTCCACCC 1080

CCATCAGTAT CATTGCCAAA GCTGGCAGCG CTTCTCCGAG TATTTAGCAC TGTGGTGAGG 1140

AGCATTGGGG AACGATTCAG CCCAATTCGG GGTCCTCCAA TTACTGAGGC ATATGTAACA 1200

GATGTTCTGT ACAGAGTAAT GAGATGTGTG ACGGCTGCAA ACCAAGTGTT TTTTTCTGAG 1260

GCTGTGTTGA CAGCTGCTAA TGAGTGTGTT GGTGTTTTGC TCGGCAGCTT GGATCCTAGC 1320

ATGACTATAC ATTGTGACAT GGTCATTACA TATGGATTAG ACCAACTGGA GAATTGCCAG 1380

ACTTGTGGTA CTGATTATAT CATCTCAGTC TTGAATTTAC TCACATTGAT TGTTGAACAG 1440

ATAAATACAA AACTTCCATC ATCATTTGTA GAAAAGCTGT TTATACCATC ATCCAAACTC 1500

CTCTTTTTAC GATATCATAA AGAAAAAGAG GTTGTTGCTG TAGCTCATGC TGTTTATCAA 1560

GCAGTGCTCA GCTTGAAGAA TATTCCTGTT TTGGAGACTG CCTATAAATT AATTTTGGGA 1620

GAAATGACTT GTGCCCTAAA CAACCTGCTA CATAGTCTAC AACTTCCTGA TGCTTGTTCA 1680

GAAATAAAAC ATGAAGCTTT TAAGAATCAT GTATTCAATG TAGACAATGC AAAATTTGTG 1740

GTCATATTTG ACCTTAGTGC CCTGACTACA ATTGGAAATG CTAAAAACTC ATTAATCGGG 1800

ATGTGGGCGC TGTCTCCAAC TGTCTTTGCA CTTCTGAGTA AGAATCTGAT GATTGTGCAC 1860

AGTGACCTGG CTGTTCACTT CCCTGCCATT CAGTATGCAG TCCTCTACAC GTTGTATTCC 1920

CATTGTACCA GGCATGATCA CTTTATATCT AGTAGCCTTA GTTCTTCCTC CCCATCTTTG 1980

TTTGATGGAG CTGTGATTAG TACTGTAACT ACAGCTACAA AGAAACATTT CTCAATTATA 2040

TTAAATCTTC TGGGAATATT GCTGAAGAAA GATAACCTTA ACCAGGATAC AAGGAAACTG 2100

TTAATGACTT GGGCTTTGGA AGTGGCTGTT TTAATGAAGA AGTCGGAAAC ATATGCACCG 2160

TTGTTCTCTC TTCCATCTTT TCATAAATTT TCCAAAGGCC TTTTAGCCAA CACCCTTGTT 2220

GAAGATGTGA ATATCTGTCT GCAGGCATGC AGCAGTCTGC ATGCTCTGTC CTCCTCCTTG 2280

CCAGACGATC TCTTGCAGAG GTGTGTTGAT GTTTGCCGTG TTCAACTAGT CCATAGTGGA 2340

ACTCGAATTC GACAAGCCTT TGGAAAGCTG TTGAAGTCAA TTCCTTTAGA TGTTGTTCTA 2400

AGCAATAACA ATCATACAGA AATTCAAGAA ATTTCTTTAG CATTAAGAAG TCACATGAGT 2460

AAAGCACCAA GTAATACATT CCATCCACAA GATTTCTCTG ATGTTATTAG TTTTATTTTG 2520

TATGGGAACT CTCATAGAAC AGGGAAGGAC AATTGGTTAG AAAGATTGTT CTATAGCTGC 2580

CAGAGACTGG ATAAACGTGA CCAATCAACA ATTCCCCGAA ACCTTCTAAA GACTGATGCT 2640

GTGCTTTGGC AGTGGGCTAT TTGGGAAGCA GCACAGTTCA CCGTCCTTTC TAAGTTGAGA 2700

ACTCCATTAG GCAGAGCGCA GGATACCTTC CAGACAATTG AAGGTATCAT TAGAAGTCTT 2760

GCAGCTCACA CGTTAAACCC TGATCAAGAT GTTAGCCAGT GGACAACTGC TGACAATGAT 2820

GAGGGGCACA GTAGCAACCA GCTTAGACTT GTTCTTCTTC TCCAGTATCT GGAAAATTTG 2880

GAGAAATTAA TGTATAATGC ATATGAAGGA TGTGCTAATG CCTTAACATC ACCACCTAAG 2940

GTCATAAGGA CTTTTTTCTA TACCAATCGT CAGACTTGTC AGGACTGGCT AACCAGGATC 3000

CGCCTGTCCA TTATGAGGGT TGGATTGTTG GCAGGCCAGC CTGCTGTGAC AGTAAGACAC 3060

GGCTTTGATT TGCTTACAGA AATGAAGACA AATAGTCTGT CTCAGGGGAA TGAATTGGAA 3120

GTAACCATTA TGATGGTGGT AGAAGCACTG TGTGAACTTC ATTGTCCTGA AGCTATACAG 3180

GGAATTGCTG TCTGGTCATC TTCCATTGTT GGGAAAAATC TTCTCTGGAT TAACTCGGTG 3240

GCCCAGCAGG CTGAAGGGAG GTTTGAAAAA GCCTCTGTGG AATACCAGGA GCACCTCTGT 3300

GCCATGACAG GTGTCGATTG CTGCATTTCT AGCTTTGACA AATCTGTTCT CACGTTGGCC 3360

AATGTTGGAC GCAATAGTGC CAGTCCCAAA CATTCTCTGA ATGGTGAATC CAGGAAAACT 3420

GTGCTGTCCA AACCAACTGA CTCTTCCCCT GAGGTTATAA ATTATTTAGG AAATAAAGCA 3480

TGTGAATGCT ACATTTCAAT TGCTGATTGG GCGGCTGTAC AGGAGTGGCA GAATGCAATC 3540

CATGACTTGA AGAAGAGCAC CAGTAGTACT TCCCTCAACC TGAAAGCTGA TTTCAACTAT 3600

ATAAAATCAC TAAGCAGCTT TGAGTCTGGA GAATTTGTTG AATGCACTGA GCAATTAGAA 3660

TTGTTACCAG GAGAAAATAT CAATCTGCTC GCTGGAGGAT CTAAAGAAAA AATAGATATG 3720

AAAAAACTAC TTCCTAACAT GTTAAGCCCA GATCCAAGGG AACTTCAGAA ATCCATTGAA 3780

GTTCAGTTGT TGAGAAGCTC TGTTTGTTTG GCAACTGCTT TAAACCACAT AGAACAGGAT 3840

CAGAAGTGGC AGTCTATAAC CGAAAATGTA GTAAAGTACT TGAAGCAAAC CTCTCGCATA 3900

GCTATTGGAC CACTGAGACT TTCTACATTA ACTGTTTCCC AGTCCTTGCC TGTTCTGAGT 3960

ACCTTACAGC TCTACTGCTC ATCTGCTTTG GAGAACACAG TTTCTAATAG ACTTTCAACA 4020

GAGGACTGTC TTATTCCCCT CTTCAGTGAA GCTTTGCGTT CATGCAAACA GCACGACGTG 4080

AGGCCATGGA TGCAGGCCTT GAGATACACT ATGTACCAGA ATCAGTTGTT GGAGAAAATT 4140

AAAGAACAAA CAGTCCCAAT TAGAAGCCAT CTCATGGAAT TAGGTCTAAC AGCAGCAAAA 4200

TTTGCTAGAA AACGGGGGAA TGTATCACTT GCAACAAGAC TTTTGGCACA ATGCAGTGAG 4260

GTTCAACTGG GGAAGACCAC CACTGCCCAG GATTTAGTCC AGCATTTTAA AAAACTGTCA 4320

ACACAAGGTC AAGTGGATGA AAAATGGGGG CCTGAACTTG ATATTGAAAA AACCAAATTG 4380

CTATATACAG CAGGCCAGTC AACACATGCA ATGGAAATGT TGAGTTCTTG TGCCATATCT 4440

TTTTGCAAGT CTGCAAAAGC TGAATATGCA GTTGCAAAAT CAATTCTGAC TCTGGCTAAG 4500

TGGATCCAGG CAGAATGGAA AGAGATCTCA GGACAGCTGA AGCAGGTGTA CAGAGCTCAG 4560

CAACAGCAGA GCTTCTCAGG TCTTTCCACT TTGTCTAAAA ACATACTTAC TCTAATAGAA 4620

CTCCCATCTG TTAATACAGT GGAAGAAGAG TATCCTCGGA TTGAGAGTGA GTCTACAGTA 4680

CATATTGGAG TTGGAGAACC TGATTTCATT TTGGGACAAT TGTATCACCT GTCTTCAGTA 4740

CAGGCACCTG AAGTAGCCAA ATCCTGGGCA GCATTGGCTA GTTGGGCATA CAGGTGGGGC 4800

AGAAAGGTGG TTGACAATGC CAGTCAGGGA GAAGGTGTTC GTCTGTTACC TAGAGAAAAA 4860

TCTGAAGTTC AAAATCTGCT TCCAGACACT ATAACGGAAG AAGAGAAAGA GAGAATATAT 4920

GGTATTCTTG GACAGGCAGT CTGTCGACCA GCAGGAATTC AGGATGAAGA TATAACCCTT 4980

CAGATAACAG AAAATGAAGA CAATGAGGAA GATGACATGG TCGATGTTAT CTGGCGCCAA 5040

TTAATATCAA GCTGCCCGTG GCTTTCGGAG CTTGATGAAA GTGCAACAGA AGGAGTTATT 5100

AAAGTGTGGA GGAAAGTTGT AGATAGAATC TTCAGCCTGT ACAAACTGTC TTGCAGTGCA 5160

TATTTTACTT TCCTTAAACT CAACGCTGGT CAAATTCCTT TAGAAGAGGA TGACCCTAGG 5220

CTACATTTAA GTCATAGAGC GGAGCAGAGC ACCGATGATG TGATTGTGAT GGCCACTCTG 5280

CGACTGCTCC GGTTGCTGGT GAAGCATGCA GGCGAGCTCC GGCAGTATCT GGAACATGGC 5340

TTGGAGACAA CACCTACTGC TCCATGGAGA GGAATTATTC CGCAGCTTTT TTCTCGCTTA 5400

AACCACCCTG AAGTGTATGT GCGCCAAAGT ATTTGTAACC TTCTCTGTCG TGTGGCTCAA 5460

GACTCCCCAC ATCTCATATT GTATCCTGCA ATAGTGGGAA CCATATCGCT CAGCAGTGAA 5520

TCCCAGGCTT CAGGAAATAA ATTTTCCTCT GCAATTCCAA CTTTACTTGG AAACATTCAA 5580

GGAGAAGAAC TGCTAGTTTC TGAATGTGAA GGAGGAAGTC CTCCTACTTC TCAGGATAGC 5640

AATAAGGATG AACCAAAAAG TGGATTAAAT GAAGACCAAG CCATGATGCA GGATTGCTAC 5700

AGCAAAATTG TAGACAAGCT GTCCTCTGCA AACCCAACTA TGGTGTTACA GGTTCAGATG 5760

CTCGTGGCTG AGCTGCGCAG GGTCACTGTG CTCTGGGACG AGCTCTGGCT GGGAGTTTTG 5820

TTACAGCAGC ACATGTATGT CTTGAGACGA ATTCAGCAGC TGGAAGATGA AGTGAAGAGA 5880

GTCCAAAACA ACAACACTTT ACGCAAAGAA GAGAAAATTG CCATCATGCG AGAGAAACAC 5940

ACGGCTTTAA TGAAGCCCAT TGTGTTTGCT CTGGAGCATG TGAGGAGCAT CACAGCGGCC 6000

CCTGCAGAAA CGCCTCATGA AAAGTGGTTT CAGGATAATT ATGGTGATGC GATTGAAAAC 6060

GCCCTTGAAA AACTGAAGAC CCCATCGAAT CCTGCAAAGC CTGGAAGCAG CTGGATTCCA 6120

TTTAAAGAGA TAATGCTGAG TTTGCAACAG AGAGCACAGA AACGGGCAAG TTATATCTTA 6180

CGTCTTGAAG AAATCAGTCC ATGGTTGGCT GCTATGACTA ACACTGAAAT TGCTCTACCT 6240

GGGGAAGTCT CAGCCAGAGA CACTGTCACA ATCCACAGTG TGGGCGGAAC CATCACAATC 6300

TTACCAACTA AAACTAAGCC CAAGAAACTT CTCTTTCTCG GATCAGATGG GAAGAGCTAT 6360

CCTTACCTTT TCAAAGGGCT GGAGGACTTA CATCTGGATG AGAGGATAAT GCAATTCTTA 6420

TCTATTGTGA ATACCATGTT TGCTACAATT AATCGACAGG AAACGCCCCG TTTCCATGCA 6480

CGACACTATT CTGTAACACC ACTGGGAACG AGGTCAGGAC TGATCCAGTG GGTGGATGGA 6540

GCCACACCCT TATTTGGTCT TTACAAACGA TGGCAACAGC GGGAAGCTGC CTTGCAAGCA 6600

CAAAAGGCCC AAGATTCCTA CCAGACTCCT CAGAATCCTG GAATTGTACC CCGTCCTAGT 6660

GAGCTTTATT ATAGTAAAAT TGGCCCTGCT TTGAAAACAG TTGGACTCAG TCTGGATGTA 6720

TCCCGACGGG ACTGGCCCCT CCATGTGATG AAGGCAGTGC TAGAGGAGTT AATGGAGGCC 6780

ACACCCCCAA ATCTCCTGGC CAAAGAGCTG TGGTCGTCCT GCACAACGCC TGATGAGTGG 6840

TGGAGAGTCA CACAGTCTTA TGCAAGGTCT ACTGCAGTCA TGTCCATGGT TGGATACATA 6900

ATTGGCCTTG GAGACAGACA TCTGGATAAT GTTCTCATAG ATATGACGAC TGGAGAAGTG 6960

GTGCACATAG ACTACAATGT TTGCTTTGAA AAAGGTAAAA GCCTTAGAGT TCCTGAGAAA 7020

GTACCTTTTC GAATGACACA AAACATTGAA ACAGCATTGG GTGTAACTGG AGTAGAAGGT 7080

GTTTTTAGGC TTTCCTGTGA GCAGGTGCTC CACATCATGC GGCGTGGCAG GGAGACGCTG 7140

CTGACATTAC TGGAGGCTTT TGTGTATGAC CCCCTGGTGG ACTGGACTGC TGGGGGCGAG 7200

GCTGGGTTTG CTGGCGCTGT CTATGGTGGA GGAGGGCAGC AGGCTGAGAG CAAGCAGAGC 7260

AAGCGAGAGA TGGAACGAGA GATCACCCGC AGCCTCTTTT CTTCCAGAGT AGCTGAAATT 7320

AAGGTGAACT GGTTTAAGAA TAGGGATGAG ATGCTGGTTG TGCTTCCCAA ACTTGATAGC 7380

AGCTTAGACG AATATCTAAG TTTGCAAGAG CAGCTGACAG ATGTGGAAAA ACTGCAAGGC 7440

AAACTGCTGG AGGAAATAGA GTTTCTAGAA GGAGCTGAAG GAGTAGATCA TCCATCTCAC 7500

ACACTCCAAC ACAGGTATTC TGAACACACT CAACTACAGA CTCAGCAAAG AGCTGTTCAA 7560

GAAGCAATCC AGGTGAAGCT GAATGAATTT GAACAGTGGA TAACACATTA TCAGGCTGCA 7620

TTCAATAATT TAGAAGCAAC ACAGCTTGCA AGTTTGCTTC AGGAGATAAG CACACAAATG 7680

GACCTTGGTC CCCCAAGTTA TGTGCCAGCA ACCGCCTTTC TGCAGAATGC GGGCCAGGCC 7740

CACTTGATTA GCCAGTGTGA GCAGCTGGAG GGGGAAGTTG GTGCTCTTCT ACAGCAGAGG 7800

CGCTCTGTGC TCCGCGGCTG TCTGGAACAG CTGCATCACT ATGCAACTGT CGCTCTGCAG 7860

TATCCAAAAG CCATATTTCA GAAACATCGA ATTGAACAGT GGAAAACTTG GATGGAAGAA 7920

CTCATCTGTA ACACCACAGT AGAGCGCTGT CAAGAACTCT ATAGGAAATA TGAAATGCAG 7980

TATGCTCCCC AACCACCCCC CACAGTATGT CAATTCATTA CTGCCACTGA AATGACCCTA 8040

CAGCGGTATG CAGCAGACAT AAACAGCAGA CTTATTCGAC AAGTGGAACG CTTGAAACAA 8100

GAAGCGGTCA CTGTGCCAGT TTGTGAAGAT CAGTTGAAAG AAATTGAACG TTGCATTAAA 8160

GTTTTTCTTC ATGAGAATGG AGAAGAAGGA TCTTTGAGTC TAGCCAGTGT CATTATTTCT 8220

GCCCTCTGTA CCCTTACAAG ACGTAACCTG ATGATGGAAG GTGCAGCCTC AAGTGCTGGG 8280

GAGCAGCTGG TTGATCTGAC TTCTCGAGAC GGAGCCTGGT TCTTAGAGGA GCTGTGCAGT 8340

ATGAGTGGAA ATGTCACCTG CTTGGTTCAG TTACTGAAGC AGTGCCATCT GGTACCACAG 8400

GACTTAGACA TCCCAAACCC TGTAGAAGCA TCTGAGGCAG TACATTTAGC CAATGGGGTA 8460

TACACCTCAT TGCAGGAATT GAATTCAAAT TTCCGCCAAA TCATATTTCC AGAAGCACTT 8520

AGATGTTTGA TGAAAGGGGA GTACACCTTA GAAAGTATGC TTCATGAACT GGACAGTCTC 8580

ATTGAGCAAA CAACTGATGG TGTTCCTCTG CAGACTCTAG TTGAATCTCT TCAAGCTTAT 8640

TTAAGAAATG CGGCTATGGG ACTCGAAGAA GAAACACATG CTCATTACAT CGATGTTGCC 8700

AGAATATTGC ATGCTCAATA TGGTGAATTA ATCCAACCAA GAAATGGCTC AGTTGATGAA 8760

ACACCAAAAA TGTCAGCTGG TCAGATGCTT TTGGTAGCAT TTGATGGCAT GTTTGCCCAA 8820

GTTGAAACTG CTTTTGGTCT ATTAGTTGAA AAGTTAAACA AGATGGAAAT TCCTGTAGCA 8880

TGGCGAAAGA TTGACATCAT ACGGGAAGCC AGGAGTACCC AAGTTAATTT TTTTGATGAT 8940

GATAATCACC GTCAGGTGCT AGAAGAGATT TTCTTTCTAA AAAGACTACA GACAATCAAG 9000

GAGTTTTTTA GACTCTGTGG TACCTTTTCT AAAACATTGT CAGGATCAAG TTCACTTGAA 9060

GAACAGAATA CTGTGAATGG GCCTGTACAG ATTGTCAATG TGAAAACCCT TTTCAGAAAC 9120

TCTTGCTTCA GTGAAGACCA AATGGCCAAG CCTATAAAGG CCTTCACAGC TGACTTTGTG 9180

AGGCAGCTCT TGATAGGACT ACCAAATCAA GCCCTTGGAC TTACGCTGTG CAGTTTTATC 9240

AGTGCCCTCG GTGTAGACAT CATAGCTCAA GTAGAGGCAA AGGACTTTGG TGCTGAAAGC 9300

AAAGTTTCTG TTGATGATCT GTGTAAGAAA GCAGTGGAGC ACAATATCCA GGTCGGGAAG 9360

TTCTCTCAAT TAGTCATGAA CAGGGCAACC GTATTAGCAA GTTCTTATGA CACTGCCTGG 9420

AAGAAGCATG ACCTGGTGCG GAGACTGGAA ACCAGCATTT CTTCCTGTAA GACAAGCCTG 9480

CAGCGGGTTC AGCTGCATAT TGCCATGTTT CAGTGGCAAC ATGAAGATCT ACTTATCAAT 9540

AGACCTCAAG CCATGTCTGT TACGCCTCCC CCCCGGTCTG CTATCCTAAC CAGTATGAAA 9600

AAGAAGCTAC ATACTCTGAG TCAAATTGAA ACTTCAATTG CAACTGTTCA GGAAAAACTA 9660

GCAGCACTTG AAGCAAGTAT TGAGCAGCGA CTTAAGTGGG CGGGTGGTGC CAACCCTGCA 9720

TTGGCTCCTG TACTACAAGA TTTTGAAGCA ACAATAGCTG AAAGAAGAAA TCTCGTCCTC 9780

AAAGAGAGCC AAAGAGCAAG TCAGGTCACT TTTCTGTGCA GCAATATCAT TCATTTTGAA 9840

AGTTTACGAA CAAGAACTGC AGAAGCCTTA AACCTGGATG CTGCATTATT TGAACTCATC 9900

AAACGGTGTC AGCAAATGTG TTCATTTGCA TCACAGTTCA ACAGTTCAGT CTCAGAGTTG 9960

GAGCTTCGTT TATTACAGAG AGTGGACACA AGTCTTGAAC ATCCCATTGG TAGCTCTGAA 10020

TGGTTTCTGT CAGCTCACAA ACAGTTGACC CAGGATATGT CTTCTCAAAG GGCAATTCAG 10080

ACAGAGAAAG AGCAACAGAT AGAGACAGTC TGTGAAACCA TCCAGAATCT TGTTGATAAT 10140

ATAAAGACTG TGCTCACTGG TCATAACCGA CAGCTTGGAG ATGTCAAACA TCTCCTAAAA 10200

GCAATGGCTA AGGATGAAGA AGCTGCTCTG GCAGATGGTG AAGATGTTCC CTATGAGAAC 10260

AGTGTTAGGC AATTCTTGAG TGAATATAAA TCATGGCAGG ACAACATTCA GACAGTTCTG 10320

TTTACATTAG TCCAGGCTAT GGGTCAGGTT CGAAGTCAAG AACATGTTGA AATGCTCCAG 10380

GAAATCACTC CCACCCTGAA GGAATTGAAA ACACAAAGTC AGAGTATCTA TAATAATTTA 10440

GTGAGTTTTG CATCACCCTT AGTCACCGAT GCAACAAATG AATGTTCAAG TCCAACGTCA 10500

TCTGCTACTT ACCAGCCATC CTTTGCTGCA GCAGTCCGGA GCAACACTGG CCAGAAGACT 10560

CAGCCAGATG TCATGTCACA GAATGCTAAA AAGCTGATTC AGAAAAATCT TGCCACATCA 10620

GCAGATACTC CACCAAGCAC CGTCCCAGGA ACTGGCAAGA GCATTGCTTG TAGTCCTAAA 10680

AAGGCTGTGA GAGACCCTAA AACTGGGAAA GCTGTGCAAG AGAGAAACTC ATATGCAGTG 10740

AGTGTGTGGA AGAGAGTGAA AGCCAAGTTA GAGGGCCGAG ATGTTGATCC GAACAGGAGG 10800

ATGTCTGTTG CTGAACAGGT TGACTATGTC ATTAAGGAAG CAACTAATCT AGATAACTTG 10860

GCTCAGCTGT ATGAAGGTTG GACAGCCTGG GTG 10893

Domain Profile

S: 3     gfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdke  62

         ++  +++il++k+kpkkll++Gsdgk+ypyL+kg+eDl+ der++q++s+vNt++a+ ++

Q: 2093  SVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINR  2152

         566789******************************************************

S: 63    tsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpi..syrykdl  120

         ++++++++r+y+V+pl+trsgli+wv+++++L+ l+k++++++a+l++q++  sy+++++

Q: 2153  QETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAqdSYQTPQN  2212

         **************************************************999*******

S: 121   stvqar.........kpklkhlkls.........levfkevlenlv...pkdllkkllle  159

         + +++r         +p+lk++ ls         l+v+k+vle+l+   p++ll+k+l++

Q: 2213  PGIVPRpselyyskiGPALKTVGLSldvsrrdwpLHVMKAVLEELMeatPPNLLAKELWS  2272

         ***************999999999999*****************99999***********

S: 160   kfpspeewfelrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafeka  219

         ++++p+ew++++++y+rs+Av+s+vgyi+gLgdrhl+n+lid++tgevvhid++v+fek+

Q: 2273  SCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKG  2332

         ************************************************************

S: 220   ktqlkvpekvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydp  279

         k+ l+vpekvPFR+T+ni++algvtgveGvfr sce+vl+++r+ +e+llt+Le+f+ydp

Q: 2333  KS-LRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDP  2391

         **.*********************************************************

S: 280   lvdwkk...................k  286

         lvdw+                    +

Q: 2392  LVDWTAggeagfagavyggggqqaeS  2417

         *****988777777666555522222

Domain Sequence
(FASTA)

SVGGTITILP TKTKPKKLLF LGSDGKSYPY LFKGLEDLHL DERIMQFLSI VNTMFATINR 60

QETPRFHARH YSVTPLGTRS GLIQWVDGAT PLFGLYKRWQ QREAALQAQK AQDSYQTPQN 120

PGIVPRPSEL YYSKIGPALK TVGLSLDVSR RDWPLHVMKA VLEELMEATP PNLLAKELWS 180

SCTTPDEWWR VTQSYARSTA VMSMVGYIIG LGDRHLDNVL IDMTTGEVVH IDYNVCFEKG 240

KSLRVPEKVP FRMTQNIETA LGVTGVEGVF RLSCEQVLHI MRRGRETLLT LLEAFVYDPL 300

VDWTAGGEAG FAGAVYGGGG QQAES 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR014009	; PIK_FAT.

Pfam

PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013