EKS-ICT-00263

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00263

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	452.0	8.1E-136	141	428	288

Status

Unreviewed

Ensembl Protein

ENSSTOP00000013610

UniProt Accession

I3MPB5;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1B

Gene Synonyms/Alias

BMPR1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000015189	ENSSTOP00000013610	ENSSTOT00000015189

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

439

Protein Sequence
(FASTA)

MPVVTSGCLG LEGSDFQCRD TPIPHQRRSI ECCTERNECN KDLHPTLPPL KNRDFVDGPI 60

HHKALLISVT VCSLLLVLII LFCYFRYKRQ ETRPRYSIGL EQDGTYIPPG ESLRDLIEQS 120

QSSGSGSGLP LLVQRTIAKQ IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR 180

ETEIYQTVLM RHENILGFIA ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDTKSMLK 240

LAYSSVSGLC HLHTEIFSTQ GKPAIAHRDL KSKNILVKKN GTCCIADLGL AVKFISDTNE 300

VDIPPNTRVG TKRYMPPEVL DESLNRNHFQ SYIMADMYSF GLILWEVARR CVSGGIVEEY 360

QLPYHDLVPT DPSYEDMREI VCIKKSRPSF PNRWSSDECL RQMGKLMTEC WAHNPASRLT 420

ALRVKKTLAK MSESQDIKL 439

Nucleotide Sequence
(FASTA)

ATGCCTGTGG TCACTTCTGG GTGTCTAGGA CTAGAAGGTT CAGATTTTCA GTGTCGGGAC 60

ACTCCTATTC CTCATCAAAG AAGATCAATT GAATGCTGCA CAGAAAGGAA TGAATGTAAT 120

AAAGACCTCC ACCCTACTTT GCCTCCACTG AAAAACAGAG ATTTTGTTGA TGGACCTATA 180

CACCACAAGG CCTTACTTAT ATCTGTGACT GTCTGTAGTT TGCTATTGGT CCTTATCATT 240

TTATTTTGTT ACTTCAGGTA TAAAAGACAA GAAACCAGAC CTCGGTACAG CATTGGGCTG 300

GAACAGGATG GAACTTACAT TCCTCCTGGA GAATCCCTGA GAGACTTAAT TGAGCAGTCT 360

CAAAGCTCAG GAAGTGGATC AGGCCTCCCT CTGCTGGTCC AAAGGACTAT AGCTAAGCAG 420

ATTCAGATGG TGAAACAGAT TGGAAAAGGT CGCTATGGGG AAGTTTGGAT GGGAAAGTGG 480

CGTGGCGAAA AGGTAGCTGT GAAAGTGTTC TTCACCACAG AGGAAGCCAG CTGGTTCAGA 540

GAGACAGAAA TCTATCAGAC AGTGTTGATG AGGCATGAAA ACATTTTGGG GTTCATTGCT 600

GCAGATATCA AAGGAACTGG GTCCTGGACC CAGCTCTACC TCATCACAGA CTATCATGAA 660

AACGGTTCCC TTTATGATTA CCTAAAGTCC ACCACCCTAG ACACTAAATC CATGTTGAAG 720

TTAGCCTACT CTTCTGTCAG TGGCTTATGT CATTTACACA CAGAAATCTT CAGTACTCAA 780

GGCAAACCAG CGATTGCACA CCGAGATCTG AAAAGTAAGA ACATCCTGGT GAAGAAAAAT 840

GGAACTTGCT GCATAGCTGA CCTGGGCCTG GCTGTTAAGT TTATTAGTGA TACAAATGAA 900

GTTGACATAC CACCCAACAC TCGTGTTGGC ACCAAGCGCT ACATGCCTCC AGAGGTGTTG 960

GACGAGAGCT TGAATAGAAA CCACTTTCAG TCTTACATCA TGGCTGATAT GTACAGTTTT 1020

GGACTCATCC TTTGGGAGGT TGCTCGGAGA TGTGTTTCAG GAGGTATAGT GGAAGAATAC 1080

CAGCTTCCCT ATCATGACCT GGTGCCCACT GACCCCTCTT ACGAGGACAT GAGAGAGATT 1140

GTGTGCATCA AGAAGTCACG GCCCTCATTC CCCAATCGCT GGAGCAGTGA TGAGTGTCTA 1200

AGGCAGATGG GGAAACTCAT GACAGAGTGC TGGGCTCACA ATCCTGCATC AAGGCTGACA 1260

GCCCTGCGTG TTAAGAAGAC ACTTGCCAAA ATGTCAGAGT CTCAGGACAT TAAACTCTGA 1320

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 141   IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  200

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+dyLk++tld++++l+la+s +sGl+hLH+ei+ t+

Q: 201   ADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKSMLKLAYSSVSGLCHLHTEIFSTQ  260

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNilvkk++tcciaDlGLa+k+ ++++e+d+  n++vGtkRYm PE

Q: 261   G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPE  318

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+++ +aD+Ys+gL+lWEva+Rc + +++veey+lp+++ v++dPs+e+m

Q: 319   VLDESLNRNHFQSYIMADMYSFGLILWEVARRCVS-GGIVEEYQLPYHDLVPTDPSYEDM  377

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +e+v+ kk rP++p++w+++e+l+++ kl++ecW+++p++Rltalrvkk+l

Q: 378   REIVCIKKSRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTL  428

         *************************************************97

Domain Sequence
(FASTA)

IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDTKSMLK LAYSSVSGLC HLHTEIFSTQ 120

GKPAIAHRDL KSKNILVKKN GTCCIADLGL AVKFISDTNE VDIPPNTRVG TKRYMPPEVL 180

DESLNRNHFQ SYIMADMYSF GLILWEVARR CVSGGIVEEY QLPYHDLVPT DPSYEDMREI 240

VCIKKSRPSF PNRWSSDECL RQMGKLMTEC WAHNPASRLT ALRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013