EKS-ICT-00205

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00205

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	563.6	1.4E-169	154	506	353

Status

Unreviewed

Ensembl Protein

ENSSTOP00000014034

UniProt Accession

I3MQ55;

Protein Name

Protein Synonyms/Alias

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000015679	ENSSTOP00000014034	ENSSTOT00000015679

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

574

Protein Sequence
(FASTA)

MAVRQALGRG LQLGRSLLLR FTAKPGPACS WGRPGPAAGW GRGERRGRAA GPGAEPRGLG 60

LPDRYRFFRQ SVVGLAARLQ RQFVVRARGG AGPYGRAVFL AFGLGLGLIE EKQAEGRRAA 120

LACQEIQAIF TQKNKPVPDA LDMRRWQGFR LEDYLIGQSI GKGCSAAVYE ATMPTLSQHL 180

EKAEPTSALP GRGPQGEEGE QALGAPAFPF AIKMMWNISA GSSSEAIFRK MSQELVPASR 240

VALTGEYGAV TYRKSKGGLK QLAPHPNIIR VVRAFTSSVP LLPGALTDYP DVLPPCLHPE 300

GLGHGRTLFL VMKNYPCTLR QYLRVNTPSP RLATMMTLQL LEGVDHLVQQ RIAHRDLKSD 360

NILVELDADG CPWLVISDFG CCLADERVGL QLPFTSWYVD LGGNGCLIPE QVSTACPGPR 420

AVIDYSKADA WAVGAIAYEI FGLANPFYGQ GRAHLESRSY QEAQLPALPE SVPLDTRQLV 480

RALLQRETSK RPSARVAANV LHLSLWGEHI LALKNLKLDK MISWLLHQSA AALLANRLEK 540

SCVETKLKVL FLANLECDAL CQAALLLYSW RVTP 574

Nucleotide Sequence
(FASTA)

ATGGCGGTGC GACAGGCGCT GGGCCGGGGC CTGCAGCTGG GTCGGTCGCT GCTGCTGCGC 60

TTCACAGCCA AGCCTGGCCC AGCTTGCAGC TGGGGAAGGC CCGGCCCGGC AGCCGGCTGG 120

GGCCGCGGAG AGCGCCGGGG CCGGGCCGCA GGACCCGGCG CAGAGCCGCG CGGGCTCGGA 180

CTCCCAGACC GCTACCGCTT TTTCCGCCAG TCGGTGGTCG GGCTGGCGGC GCGGCTCCAG 240

CGGCAGTTCG TGGTGCGGGC CCGGGGAGGC GCGGGCCCTT ATGGCCGAGC CGTCTTTCTG 300

GCCTTCGGGC TGGGGTTGGG CCTCATAGAG GAGAAGCAGG CGGAGGGCCG GCGGGCGGCG 360

CTAGCCTGTC AGGAGATCCA GGCAATATTT ACCCAGAAAA ACAAGCCAGT GCCTGACGCG 420

CTGGACATGC GACGCTGGCA GGGCTTCCGG CTGGAGGACT ATCTGATAGG ACAGTCCATC 480

GGCAAGGGCT GCAGCGCTGC TGTGTATGAA GCCACCATGC CCACCCTGTC CCAGCACCTG 540

GAGAAGGCAG AGCCCACCAG CGCTCTTCCA GGGAGAGGCC CACAAGGAGA GGAAGGGGAG 600

CAGGCTCTGG GAGCCCCAGC CTTCCCCTTC GCCATCAAGA TGATGTGGAA CATCTCGGCG 660

GGCTCTTCCA GTGAAGCCAT TTTTAGGAAG ATGAGCCAGG AGCTGGTCCC AGCTAGCAGA 720

GTGGCCCTGA CTGGGGAGTA TGGAGCAGTT ACTTACAGAA AATCCAAGGG AGGTCTCAAA 780

CAGCTAGCTC CTCACCCCAA CATCATCCGG GTTGTCCGCG CCTTCACCTC CTCTGTGCCG 840

CTGCTGCCGG GGGCCCTGAC CGACTACCCT GACGTGCTGC CCCCTTGTCT GCACCCTGAA 900

GGCCTGGGCC ATGGACGCAC GCTGTTCCTC GTTATGAAAA ACTACCCCTG TACCCTGCGC 960

CAGTACCTGC GTGTGAACAC TCCTAGTCCC CGCCTGGCCA CCATGATGAC CCTGCAGTTA 1020

CTGGAAGGCG TGGACCATTT GGTCCAGCAG CGCATCGCAC ATAGAGACCT CAAGTCGGAC 1080

AACATTCTGG TGGAGCTGGA TGCAGACGGC TGCCCCTGGT TGGTGATCTC TGATTTTGGC 1140

TGCTGCCTGG CTGATGAGCG TGTGGGCCTG CAGTTGCCTT TCACCAGCTG GTACGTGGAC 1200

CTGGGCGGGA ACGGCTGCCT CATTCCCGAG CAGGTATCCA CAGCCTGTCC TGGCCCCAGA 1260

GCAGTGATTG ACTACAGCAA GGCCGACGCC TGGGCGGTGG GAGCCATCGC CTATGAAATC 1320

TTCGGGCTCG CCAATCCCTT TTACGGCCAG GGCAGGGCCC ACCTTGAAAG CCGCAGTTAC 1380

CAAGAGGCTC AACTACCAGC ACTGCCCGAG TCGGTGCCTC TAGACACCAG GCAGCTGGTG 1440

AGGGCATTGC TCCAGCGAGA GACCAGCAAG AGACCATCTG CCCGAGTAGC TGCAAACGTG 1500

CTTCATCTGA GCCTCTGGGG CGAGCACATC CTAGCCCTGA AGAATCTGAA ATTAGACAAG 1560

ATGATTAGCT GGCTCCTCCA CCAATCAGCT GCTGCCCTGT TGGCCAACAG GCTGGAGAAG 1620

AGCTGCGTGG AAACAAAGCT GAAGGTGCTG TTCCTGGCCA ACCTGGAGTG TGACGCGCTC 1680

TGCCAGGCTG CCCTCCTCCT CTACTCCTGG CGGGTAACCC CC 1722

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll.gkevtvvlaeidqesavaakkfp  59

         ylig+++gkgc+aavyeat++tl q+leka+ + +l g+++    +++++e+a +a++fp

Q: 154   YLIGQSIGKGCSAAVYEATMPTLSQHLEKAEPTSALpGRGP----QGEEGEQALGAPAFP  209

         99*****************************9999878888....5899***********

S: 60    laiklmfnieadssseallksmsqelvpasrvaldgeygav........pkllakhPniv  111

         +aik+m+ni+a+sssea++++msqelvpasrval geygav         k+la+hPni+

Q: 210   FAIKMMWNISAGSSSEAIFRKMSQELVPASRVALTGEYGAVtyrkskggLKQLAPHPNII  269

         **********************************************999999********

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

         rv+raf++sv+llP+al+dyPd+lp+ l+peglg+g+tl+lvmk+y++tlr+yl ++++s

Q: 270   RVVRAFTSSVPLLPGALTDYPDVLPPCLHPEGLGHGRTLFLVMKNYPCTLRQYLRVNTPS  329

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

         +rla+++++qlle+vdhlv++++ahrdlksdnilveld d++P+lvi+dfGCclad+ +g

Q: 330   PRLATMMTLQLLEGVDHLVQQRIAHRDLKSDNILVELDADGCPWLVISDFGCCLADERVG  389

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         l+lp++s++vd GGn++l   ++sta pGp+avi+y+kad+WavGa+ayeifgl+nPfyg

Q: 390   LQLPFTSWYVDLGGNGCLIPEQVSTACPGPRAVIDYSKADAWAVGAIAYEIFGLANPFYG  449

         ************************************************************

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

         +g+a+les+syqeaqlPalpesvp + rqlv++ll+re+skr+sa++aanvl+lsl+

Q: 450   QGRAHLESRSYQEAQLPALPESVPLDTRQLVRALLQRETSKRPSARVAANVLHLSLW  506

         ********************************************************9

Domain Sequence
(FASTA)

YLIGQSIGKG CSAAVYEATM PTLSQHLEKA EPTSALPGRG PQGEEGEQAL GAPAFPFAIK 60

MMWNISAGSS SEAIFRKMSQ ELVPASRVAL TGEYGAVTYR KSKGGLKQLA PHPNIIRVVR 120

AFTSSVPLLP GALTDYPDVL PPCLHPEGLG HGRTLFLVMK NYPCTLRQYL RVNTPSPRLA 180

TMMTLQLLEG VDHLVQQRIA HRDLKSDNIL VELDADGCPW LVISDFGCCL ADERVGLQLP 240

FTSWYVDLGG NGCLIPEQVS TACPGPRAVI DYSKADAWAV GAIAYEIFGL ANPFYGQGRA 300

HLESRSYQEA QLPALPESVP LDTRQLVRAL LQRETSKRPS ARVAANVLHL SLW 353

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>