EKS-ICT-00154

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00154

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	617.4	2.7E-186	163	441	279

Status

Unreviewed

Ensembl Protein

ENSSTOP00000014054

UniProt Accession

I3MQ72;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK1

Gene Synonyms/Alias

TLK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000015694	ENSSTOP00000014054	ENSSTOT00000015700

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

473

Protein Sequence
(FASTA)

MQDRLRLGHF TTVRHGASFT EQWTDGFAFQ NLVKQQEWVN QQREDIERQR KLLAKRKPPT 60

ANNSQAPSTN SEPKQRKNKA VNGAENDPFV RPNLPQLLTL AEYHEQEEIF KLRLGHLKKE 120

EAEIQAELER LERVRNLHIR ELKRINNEDN SQFKDHPTLN ERYLLLHLLG RGGFSEVYKA 180

FDLYEQRYAA VKIHQLNKSW RDEKKENYHK HACREYRIHK ELDHPRIVKL YDYFSLDTDT 240

FCTVLEYCEG NDLDFYLKQH KLMSEKEARS IVMQIVNALR YLNEIKPPII HYDLKPGNIL 300

LVDGTACGEI KITDFGLSKI MDDDSYGVDG MDLTSQGAGT YWYLPPECFV VGKEPPKISN 360

KVDVWSVGVI FFQCLYGRKP FGHNQSQQDI LQENTILKAT EVQFPVKPVV SSEAKAFIRR 420

CLAYRKEDRF DVHQLANDPY LLPHMRRSNS SGNLHMAGLT ASPTPPSSSI ITY 473

Nucleotide Sequence
(FASTA)

ATGCAAGATA GATTACGCCT TGGGCACTTT ACAACAGTTA GACATGGCGC TTCATTTACT 60

GAACAATGGA CAGATGGTTT TGCATTTCAG AATCTTGTGA AGCAACAAGA ATGGGTGAAT 120

CAGCAAAGGG AAGATATTGA ACGGCAAAGG AAACTTCTAG CCAAACGCAA ACCTCCCACA 180

GCTAATAATT CTCAGGCACC TTCTACCAAT TCTGAACCAA AACAAAGAAA AAACAAAGCA 240

GTCAATGGAG CAGAAAATGA TCCCTTTGTT AGACCAAATT TACCACAACT GTTGACTTTG 300

GCAGAATATC ATGAACAGGA AGAAATTTTC AAACTTAGAC TAGGACATCT CAAAAAGGAA 360

GAGGCAGAAA TCCAGGCAGA ACTTGAACGT TTGGAAAGAG TCAGAAATCT TCACATACGG 420

GAGCTCAAAA GAATAAACAA TGAAGATAAT TCACAGTTCA AAGATCACCC AACATTAAAT 480

GAAAGGTATT TATTACTTCA TCTGCTTGGA AGAGGTGGCT TTAGTGAAGT ATATAAGGCT 540

TTTGACCTAT ATGAACAAAG ATATGCTGCT GTGAAGATCC ATCAGCTTAA TAAAAGCTGG 600

AGAGATGAGA AAAAAGAAAA CTACCACAAG CATGCCTGCA GAGAGTATAG AATACACAAA 660

GAACTGGATC ACCCCAGAAT AGTTAAACTC TATGATTATT TTTCCTTGGA CACAGATACG 720

TTTTGTACAG TGTTAGAATA CTGTGAAGGC AATGACTTGG ATTTCTATCT GAAGCAACAT 780

AAATTAATGT CAGAGAAAGA AGCTAGGTCT ATTGTAATGC AGATTGTAAA TGCACTAAGA 840

TATCTCAATG AGATCAAACC TCCTATTATA CATTATGATC TTAAACCAGG AAATATCCTC 900

CTGGTAGATG GAACAGCATG TGGAGAAATC AAGATCACCG ATTTTGGTCT GTCCAAGATT 960

ATGGATGATG ATAGCTATGG TGTAGATGGA ATGGATCTAA CTTCCCAAGG GGCAGGCACT 1020

TACTGGTATT TACCTCCAGA GTGTTTTGTA GTTGGAAAAG AGCCACCAAA GATTTCCAAT 1080

AAGGTCGATG TATGGTCAGT TGGCGTCATC TTCTTTCAGT GTCTTTATGG TAGAAAGCCA 1140

TTTGGTCACA ATCAATCTCA ACAAGACATT CTTCAAGAAA ATACAATATT AAAAGCCACA 1200

GAAGTCCAGT TCCCTGTTAA ACCAGTTGTA AGCAGTGAAG CCAAGGCCTT CATACGACGC 1260

TGTTTAGCAT ACCGAAAAGA GGATCGATTT GATGTTCACC AACTGGCAAA TGACCCATAC 1320

CTTCTCCCAC ACATGAGAAG ATCAAATTCT TCAGGAAACT TACACATGGC TGGGCTGACA 1380

GCATCCCCTA CGCCCCCTTC TTCAAGCATA ATTACTTACT GA 1422

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqry+avkihqlnk+w+dekkeny+kha+reyrihkel

Q: 163   YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKEL  222

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtd+fctvley+egndldfylkqhkl+sekearsi+mqiv+al+yl

Q: 223   DHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYL  282

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimdddsy++d g++ltsqgagty

Q: 283   NEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD-GMDLTSQGAGTY  341

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvif+qclyg+kpfghnqsqqdil+entilkate

Q: 342   WYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATE  401

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvvsseakafirrclayrkedr+dv+qla+d+yl

Q: 402   VQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYL  441

         **************************************97

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LYEQRYAAVK IHQLNKSWRD EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDTFC TVLEYCEGND LDFYLKQHKL MSEKEARSIV MQIVNALRYL 120

NEIKPPIIHY DLKPGNILLV DGTACGEIKI TDFGLSKIMD DDSYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGVIFF QCLYGRKPFG HNQSQQDILQ ENTILKATEV 240

QFPVKPVVSS EAKAFIRRCL AYRKEDRFDV HQLANDPYL 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013