EKS-ICT-00264

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00264

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	447.1	2.5E-134	206	493	288

Status

Unreviewed

Ensembl Protein

ENSSTOP00000014184

UniProt Accession

I3MQG4;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000015838	ENSSTOP00000014184	ENSSTOT00000015846

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

504

Protein Sequence
(FASTA)

MLHGTGMKSD SDQKKSENGV TLAPEDTLPF LKCYCSGHCP DDAINNTCIT NGHCFAIIEE 60

DDQGETTLAS GCMKYEGSDF QCKDSPKAQL RRTIECCRTN LCNQYLQPTL PPVVIGPFFD 120

GSIRWLVVLI SMAVCIIAMI IFSSCFCYKH YCKGISSRRR YNRDLEQDEA FIPVGESLKD 180

LIDQSQSSGS GSGLPLLVQR TIAKQIQMVR QVGKGRYGEV WMGKWRGEKV AVKVFFTTEE 240

ASWFRETEIY QTVLMRHENI LGFIAADIKG TGSWTQLYLI TDYHENGSLY DFLKCATLDT 300

RALLKLAYSA ACGLCHLHTE IYGTQGKPAI AHRDLKSKNI LIKKNGSCCI ADLGLAVKFN 360

SDTNEVDVPL NTRVGTKRYM APEVLDESLN KNHFQPYIMA DIYSFGLIIW EMARRCITGG 420

IVEEYQLPYY NMVPSDPSYE DMREVVCVKR LRPIVSNRWN SDECLRAVLK LMSECWAHNP 480

ASRLTALRIK KTLAKMVESQ DVKI 504

Nucleotide Sequence
(FASTA)

ATGCTCCATG GCACTGGGAT GAAATCAGAC TCCGACCAGA AGAAGTCAGA AAATGGAGTG 60

ACATTAGCAC CAGAGGATAC CTTGCCTTTT TTAAAGTGCT ATTGCTCAGG ACACTGCCCA 120

GATGATGCTA TTAATAACAC ATGCATAACT AATGGTCATT GCTTTGCCAT CATAGAAGAA 180

GATGATCAGG GAGAAACCAC ATTAGCTTCA GGATGTATGA AATATGAAGG ATCTGATTTT 240

CAGTGCAAGG ATTCACCAAA AGCCCAACTT CGCCGTACAA TAGAATGTTG TCGGACCAAT 300

TTATGTAACC AGTATTTACA ACCTACACTG CCCCCTGTTG TTATAGGTCC ATTTTTTGAT 360

GGCAGCATTC GATGGCTGGT TGTTCTCATT TCCATGGCTG TTTGCATAAT TGCTATGATC 420

ATCTTCTCCA GCTGCTTTTG TTACAAACAT TATTGCAAGG GCATCTCAAG CAGACGTCGT 480

TACAATCGCG ATTTGGAACA GGATGAAGCA TTTATTCCAG TGGGAGAATC ATTAAAAGAC 540

CTTATTGATC AGTCACAGAG TTCTGGTAGT GGATCTGGAT TACCATTATT GGTTCAGAGA 600

ACTATTGCCA AACAGATTCA GATGGTTCGG CAAGTTGGTA AAGGCCGGTA TGGAGAAGTG 660

TGGATGGGTA AATGGCGTGG TGAAAAAGTG GCAGTCAAAG TGTTTTTTAC CACTGAAGAA 720

GCTAGCTGGT TTCGAGAAAC GGAAATCTAC CAAACTGTGC TAATGCGCCA TGAAAATATA 780

CTTGGTTTTA TAGCAGCAGA TATTAAAGGC ACAGGTTCCT GGACTCAACT CTATTTGATT 840

ACTGATTATC ATGAAAATGG ATCTCTCTAT GACTTCCTGA AATGTGCTAC ACTAGACACC 900

AGAGCCCTGC TCAAGTTGGC TTATTCAGCT GCCTGTGGTC TGTGCCACCT CCACACAGAA 960

ATTTATGGCA CCCAAGGAAA GCCTGCAATT GCTCATCGAG ATCTAAAGAG CAAAAATATC 1020

CTCATCAAGA AAAATGGAAG TTGCTGCATT GCTGACCTGG GCCTTGCTGT TAAATTCAAC 1080

AGTGATACAA ATGAAGTTGA TGTGCCCTTG AATACCAGAG TGGGAACCAA ACGTTATATG 1140

GCTCCAGAAG TGCTAGATGA AAGCCTGAAT AAAAACCATT TCCAGCCTTA TATAATGGCT 1200

GACATCTATA GCTTTGGCCT GATCATTTGG GAAATGGCTC GTCGTTGTAT CACAGGAGGG 1260

ATAGTAGAGG AGTACCAATT GCCATATTAC AACATGGTAC CCAGTGACCC ATCCTATGAA 1320

GATATGCGTG AGGTTGTATG TGTCAAACGT TTGCGGCCAA TTGTGTCTAA CCGATGGAAC 1380

AGTGATGAAT GTCTACGAGC AGTTTTGAAG CTGATGTCAG AATGCTGGGC CCACAATCCA 1440

GCCTCCAGAC TTACAGCATT GAGAATCAAG AAGACACTTG CGAAGATGGT GGAATCCCAA 1500

GATGTAAAGA TTTGA 1515

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         +++++++gkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 206   IQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  265

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+d+Lk  tld++ ll+la+s+a+Gl+hLH+ei gt+

Q: 266   ADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQ  325

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNil+kk+++cciaDlGLa+k++++++e+d+  n++vGtkRYmaPE

Q: 326   G--KPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPE  383

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+ + +aD+Ys+gL++WE+a+Rc + +++veey+lp++++v+sdPs+e+m

Q: 384   VLDESLNKNHFQPYIMADIYSFGLIIWEMARRCIT-GGIVEEYQLPYYNMVPSDPSYEDM  442

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +evv++k+lrP ++++w+++e+l+++ kl++ecW+++p++Rltalr+kk+l

Q: 443   REVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTL  493

         *************************************************97

Domain Sequence
(FASTA)

IQMVRQVGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDFLKC ATLDTRALLK LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GSCCIADLGL AVKFNSDTNE VDVPLNTRVG TKRYMAPEVL 180

DESLNKNHFQ PYIMADIYSF GLIIWEMARR CITGGIVEEY QLPYYNMVPS DPSYEDMREV 240

VCVKRLRPIV SNRWNSDECL RAVLKLMSEC WAHNPASRLT ALRIKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013