EPS-ICT-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ICT-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	272.9	3.3E-81	63	373	311

Status

Unreviewed

Ensembl Protein

ENSSTOP00000019431

UniProt Accession

I3N4Y5;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000021256	ENSSTOP00000019431	ENSSTOT00000021653

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

605

Protein Sequence
(FASTA)

MAGLYSLGVS VFSDQGGRKY MEDVTQIVVE PEPTAEEKPS PRRALSQQSP ARRSLAPLPG 60

SEVSGKGPAA AARDAHDPPP DAGASPAPGR CCRRRSSVAF FAVCDGHGGR EAAQFAREHL 120

WGFIKKQKGF TSSEPAKVCA AIRKGFLACH LAMWKKLAEW PKTMTGLPST SGTTASVVII 180

RGMKMYVAHV GDSGVVLGIQ DDPKDDFIRA VEVTQDHKPE LPKERERIEG LGGSVMNKSG 240

VNRVVWKRPR LTHNGPVRRS TVIDQIPFLA VARALGDLWS YDFFSGEFVV SPEPDTSVHT 300

LDPQKHRYII LGSDGLWNMI PPQDAISMCQ DQEDKKYLMG EPGQSCAKML VNRALGRWRQ 360

RMLRADNTSA IVICISPGVD NQGHFTNEDE LYLNLTDSPS YNSQETCVMT PSPCSTPPVK 420

SLEEEQWPRL NSKDHIPALV RSNAFSENFL EVPAEIARGS VQAVVIPSKD PEPLEENCTK 480

ALTLRIHDSL NNTLSVGLMP TNSTNAILDQ KNLKMSTPGQ MKAQEVERTP PANFKRTLEE 540

SNSGPLMKKH RRNGLSRSSG AQPGSLPTTS QRKNSVKLTM RRRLRGHRKI GNPLLHQHRK 600

TVCVC 605

Nucleotide Sequence
(FASTA)

ATGGCGGGGC TGTACTCGCT GGGAGTGAGC GTCTTCTCTG ACCAGGGCGG GAGGAAGTAC 60

ATGGAGGACG TTACCCAGAT CGTGGTGGAG CCCGAGCCGA CGGCTGAAGA AAAGCCGTCG 120

CCGCGGCGGG CGCTCTCGCA GCAGTCGCCT GCGCGGCGGT CCCTGGCCCC TCTTCCAGGC 180

AGCGAAGTGT CGGGGAAAGG CCCAGCGGCG GCAGCCCGCG ACGCTCACGA CCCTCCCCCG 240

GACGCCGGGG CCTCACCAGC GCCCGGCCGC TGCTGCCGCC GCCGTTCCTC TGTTGCCTTT 300

TTCGCGGTGT GCGACGGGCA CGGCGGGCGG GAGGCGGCAC AGTTTGCCCG CGAGCACTTA 360

TGGGGTTTCA TCAAGAAGCA GAAGGGTTTC ACCTCGTCGG AGCCGGCGAA GGTTTGCGCT 420

GCCATCCGCA AAGGCTTCCT TGCCTGTCAC CTCGCCATGT GGAAGAAACT GGCAGAATGG 480

CCGAAGACTA TGACAGGTCT TCCTAGCACA TCTGGGACAA CTGCCAGTGT GGTCATCATA 540

CGGGGCATGA AGATGTATGT AGCTCACGTG GGTGATTCTG GGGTGGTCCT TGGAATTCAA 600

GATGACCCGA AGGATGATTT TATCAGAGCT GTGGAGGTGA CACAGGATCA TAAGCCAGAA 660

CTTCCCAAGG AAAGAGAACG AATTGAAGGA CTTGGTGGCA GTGTCATGAA CAAGTCTGGG 720

GTGAACCGTG TAGTTTGGAA AAGACCTCGG CTCACTCACA ATGGACCTGT TAGAAGGAGC 780

ACAGTTATTG ACCAGATTCC CTTTCTGGCA GTAGCAAGAG CACTTGGTGA TTTGTGGAGC 840

TATGATTTCT TCAGTGGTGA GTTTGTGGTT TCACCTGAAC CAGACACAAG TGTCCACACT 900

CTTGATCCTC AGAAGCACAG ATATATCATC TTGGGGAGTG ATGGACTTTG GAATATGATT 960

CCACCCCAGG ATGCCATCTC AATGTGCCAG GACCAAGAGG ATAAAAAATA CTTGATGGGT 1020

GAGCCTGGAC AATCTTGTGC CAAAATGCTT GTGAATCGGG CACTAGGCCG CTGGAGGCAG 1080

CGTATGCTTC GGGCAGATAA CACCAGTGCC ATAGTAATCT GCATCTCTCC AGGAGTGGAC 1140

AATCAGGGAC ACTTCACCAA TGAAGATGAG CTCTATCTGA ACCTGACTGA TAGCCCTTCT 1200

TATAATAGTC AGGAAACCTG TGTTATGACT CCTTCTCCAT GTTCTACACC ACCAGTCAAG 1260

TCTCTGGAAG AGGAGCAATG GCCAAGGCTG AACTCCAAGG ACCATATACC TGCCCTTGTT 1320

CGTAGTAATG CCTTCTCAGA GAATTTTTTA GAGGTCCCAG CTGAGATAGC TCGAGGGAGC 1380

GTCCAGGCTG TAGTTATACC CTCAAAAGAT CCAGAGCCAC TTGAAGAAAA TTGCACTAAA 1440

GCCCTGACTT TAAGGATACA CGATTCTTTG AATAATACCC TGTCAGTTGG CCTTATGCCT 1500

ACAAATTCAA CAAATGCCAT CTTGGACCAA AAAAACTTAA AGATGTCAAC TCCTGGTCAA 1560

ATGAAAGCTC AAGAAGTTGA AAGAACCCCT CCAGCGAACT TTAAAAGGAC ATTAGAAGAA 1620

TCCAACTCTG GCCCCCTTAT GAAGAAACAT AGACGAAATG GCTTAAGCCG AAGTAGTGGT 1680

GCTCAACCTG GAAGCCTCCC CACAACCTCA CAGCGGAAGA ACTCTGTCAA ACTCACTATG 1740

CGACGTAGAC TTAGGGGCCA CCGAAAAATT GGAAATCCTT TACTACATCA GCACAGGAAA 1800

ACTGTTTGTG TTTGCTGA 1818

Domain Profile

S: 6     vsvngrrnemedavtsspnflkspekkdr......laffgvyDGhggsevakfcseklhe  59

         vs++g+    +da+++ p++++sp+  ++      +aff+v+DGhgg+e+a+f++e+l+

Q: 63    VSGKGPAAAARDAHDPPPDAGASPAPGRCcrrrssVAFFAVCDGHGGREAAQFAREHLWG  122

         7899999********************99*******************************

S: 60    ilaeelesseseerkvkkalakaFlstdeel.....kvleeksldidksGstavvalikd  114

         ++++++ +++se +kv++a++k+Fl+++ ++     +++++++  +++sG+ta+v++i++

Q: 123   FIKKQKGFTSSEPAKVCAAIRKGFLACHLAMwkklaEWPKTMTGLPSTSGTTASVVIIRG  182

         ************************************************************

S: 115   sklyvanvGdSravLcrngk.......avelssdHkpsredEleRieeaggsvilkdga.  166

         +k+yva+vGdS++vL+ +++       ave+++dHkp+ ++E+eRie  ggsv++k+g+

Q: 183   MKMYVAHVGDSGVVLGIQDDpkddfirAVEVTQDHKPELPKERERIEGLGGSVMNKSGVn  242

         *****************77656999999********************************

S: 167   Rv.....................lGvLavsRalGdlylk......pyvtpePevtshrlt  199

         Rv                     +++Lav+RalGdl+++      ++v+peP++++h+l+

Q: 243   RVvwkrprlthngpvrrstvidqIPFLAVARALGDLWSYdffsgeFVVSPEPDTSVHTLD  302

         ************************************************************

S: 200   sede.fliLasDGlwdvvsneeavslvrdvle....kkeaeqeaakkLvklalargsk..  252

         ++++ ++iL+sDGlw+++++++a+s+++d+++    ++e+ q++ak+Lv++al r+++

Q: 303   PQKHrYIILGSDGLWNMIPPQDAISMCQDQEDkkylMGEPGQSCAKMLVNRALGRWRQrm  362

         ************************************************************

S: 253   ...dnvsaivv  260

            dn+saiv+

Q: 363   lraDNTSAIVI  373

         *********97

Domain Sequence
(FASTA)

VSGKGPAAAA RDAHDPPPDA GASPAPGRCC RRRSSVAFFA VCDGHGGREA AQFAREHLWG 60

FIKKQKGFTS SEPAKVCAAI RKGFLACHLA MWKKLAEWPK TMTGLPSTSG TTASVVIIRG 120

MKMYVAHVGD SGVVLGIQDD PKDDFIRAVE VTQDHKPELP KERERIEGLG GSVMNKSGVN 180

RVVWKRPRLT HNGPVRRSTV IDQIPFLAVA RALGDLWSYD FFSGEFVVSP EPDTSVHTLD 240

PQKHRYIILG SDGLWNMIPP QDAISMCQDQ EDKKYLMGEP GQSCAKMLVN RALGRWRQRM 300

LRADNTSAIV I 311

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>