EPS-ICT-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ICT-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	188.5	1.7E-55	294	540	247

Status

Unreviewed

Ensembl Protein

ENSSTOP00000023397

UniProt Accession

I3NGA0;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000022464	ENSSTOP00000023397	ENSSTOT00000022763

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

832

Protein Sequence
(FASTA)

LTAVNVYPVP SLLTSLELSR NLLECVPDWA CEAKKLEILD VSYNLLTEVP MRILSSLSLR 60

KLMVGHNHVH SLPVLVEHIP LEVLDIQHNV LTKLPDTLFS KALNLRYLNA SANSLESLPS 120

ACAGEESLSV LQLLYLTSNL LTDQCIPVLV GHPHLRILHL ANNQLQTFPA SKLNKLEQLE 180

ELNLSGNKLK TIPTTIANCR RLHTLVAHSN NISIFPEILQ LPQIQFVDLS CNDLTEILIP 240

EALPATLQDL DLTGNTNLVL EHKTLDMFSH ITTLKIDQKP LPTTDSTVTS TFWSHGLAEM 300

AGQRNKLCVS SLAMDNFAEG VGAVYGMFDG DRNEELPRLL QCTMADVLLE EVQQSTNDTV 360

FMTNTFLVSH RKLGMAGQKL GSSALLCYIR PDTADPTSSF SLTVANVGTC QAVLCRGGKP 420

VPLSKVFSLE QDLEEARRVK DQKAIITEDN KVNGVTCCTR MLGCTYLYPW ILPKPHISST 480

PLTIQDELLI LGNRALWEHL SYTEAINAVR HVQDPLAASK KLCTLAQSYG CQDNVGAMVV 540

YLNIGEEGCT CEMNGLTLPG PVGFASTSTI KDAPKPTTPS SSSGIASEFS SEMSTSEVSS 600

EVGSTASDEH NTVGLEAGLL PRPERRCSLH PAPTSGVFQR QPSCATFSSN QSDNGLDSDD 660

DQPVEGVIIN GSKVEVEVDI HCCRGRDLES CPTLTENSST PCPEEHARGL FFGIRRQNSV 720

NSGILLPMCR DKMELQKSPS TSCLYGKKLS NGSIVPLEDS LNLIEVATEA PKRKTGYFAA 780

PTQLEPEDQF VVPRDLEEEV KEQMKQHQES RPEPEPSEED RTEPPEEFDT AL 832

Nucleotide Sequence
(FASTA)

CTGACTGCAG TAAATGTCTA CCCGGTGCCC AGTCTCCTCA CTTCTTTGGA GCTCTCCCGA 60

AACCTGTTAG AGTGTGTTCC AGACTGGGCT TGTGAAGCAA AGAAGCTGGA AATATTAGAT 120

GTGAGCTATA ATCTTCTCAC AGAAGTTCCT ATGCGAATTC TGAGTAGCTT GAGTCTTAGG 180

AAACTGATGG TGGGACACAA TCATGTCCAC AGCCTTCCGG TGCTAGTGGA GCACATCCCT 240

CTGGAGGTGC TGGATATCCA GCATAATGTT CTCACCAAGT TGCCGGACAC CCTCTTCTCC 300

AAGGCCTTAA ATCTCAGATA CTTGAATGCA TCTGCAAACA GTCTGGAGTC TTTACCTTCT 360

GCCTGTGCTG GGGAGGAAAG TCTGAGTGTG CTGCAGCTGC TTTACCTGAC CAGCAACCTC 420

CTCACAGATC AGTGCATACC TGTCCTTGTG GGGCATCCAC ACCTTCGAAT CTTGCATCTC 480

GCAAACAACC AGCTACAGAC CTTTCCCGCA AGTAAACTAA ATAAATTGGA GCAATTGGAG 540

GAACTGAACT TAAGTGGCAA CAAGCTTAAA ACCATTCCTA CAACCATAGC CAACTGCAGA 600

AGGCTGCACA CCCTTGTTGC ACACTCTAAC AACATCAGCA TTTTCCCAGA AATATTGCAG 660

TTGCCTCAGA TCCAGTTTGT AGACCTAAGT TGCAACGACT TGACAGAAAT TCTAATTCCA 720

GAGGCTCTGC CTGCTACGTT ACAAGACCTT GACCTAACTG GAAACACAAA TCTGGTTCTG 780

GAACACAAGA CACTGGACAT GTTTAGCCAC ATCACAACCC TGAAAATTGA TCAAAAACCA 840

TTGCCAACCA CAGATTCTAC TGTTACATCA ACCTTCTGGA GCCATGGACT GGCTGAGATG 900

GCAGGACAGA GAAATAAGCT ATGTGTGTCT TCCCTAGCTA TGGATAACTT TGCAGAGGGG 960

GTTGGAGCTG TATATGGCAT GTTTGATGGG GACCGAAATG AGGAGCTTCC ACGCCTGCTG 1020

CAATGTACAA TGGCAGATGT GCTTTTGGAA GAGGTACAGC AGTCAACAAA TGACACAGTT 1080

TTCATGACCA ACACTTTTTT GGTATCTCAC AGGAAATTAG GAATGGCTGG TCAGAAGCTG 1140

GGTTCCTCTG CTCTTCTGTG CTACATCCGC CCTGACACTG CTGATCCAAC AAGTAGTTTT 1200

AGCTTGACTG TGGCTAATGT TGGCACGTGC CAAGCAGTCC TGTGCCGAGG TGGGAAGCCA 1260

GTGCCCCTTT CGAAAGTTTT CAGCCTGGAA CAGGACCTGG AGGAGGCACG AAGGGTGAAG 1320

GATCAAAAAG CCATCATTAC AGAGGATAAC AAAGTGAATG GGGTAACCTG TTGTACCCGG 1380

ATGCTGGGCT GTACATACCT TTATCCTTGG ATCCTCCCCA AGCCCCATAT ATCTTCCACA 1440

CCACTTACTA TTCAAGATGA ATTGCTGATT CTGGGAAACA GAGCATTATG GGAACACTTG 1500

TCATATACAG AAGCTATTAA TGCAGTGCGT CACGTACAAG ATCCATTAGC AGCTTCTAAG 1560

AAACTGTGCA CATTAGCACA GAGCTATGGC TGTCAGGATA ATGTGGGGGC CATGGTGGTT 1620

TATTTGAACA TTGGTGAGGA AGGCTGCACT TGTGAAATGA ATGGACTCAC CCTCCCAGGA 1680

CCTGTGGGAT TTGCTTCCAC CAGCACCATC AAGGATGCTC CTAAACCAAC CACTCCTTCC 1740

TCCAGTAGTG GCATTGCCTC TGAGTTCAGC AGTGAGATGT CCACCTCGGA GGTGAGCAGT 1800

GAAGTGGGCT CCACTGCTTC TGATGAACAT AACACTGTGG GCCTGGAGGC TGGTTTGCTT 1860

CCACGGCCAG AGAGGCGCTG CAGCCTCCAC CCAGCACCCA CCTCTGGGGT GTTTCAGCGC 1920

CAGCCTTCTT GTGCAACCTT CTCTAGTAAT CAGTCTGACA ATGGCCTTGA CAGTGATGAT 1980

GACCAGCCTG TTGAAGGGGT CATAATCAAT GGCAGCAAGG TAGAAGTAGA AGTAGATATC 2040

CACTGCTGCC GAGGAAGAGA TCTTGAGAGC TGTCCTACCC TTACAGAGAA TTCTTCCACC 2100

CCATGTCCTG AGGAACATGC TAGAGGGTTG TTTTTTGGGA TCCGGAGACA GAACAGTGTA 2160

AATAGTGGCA TACTTCTGCC AATGTGTAGG GACAAAATGG AGTTACAGAA GTCTCCTTCT 2220

ACTTCCTGTC TCTATGGCAA GAAGCTCTCC AATGGCTCAA TTGTGCCCCT AGAAGATAGC 2280

CTGAACCTCA TTGAAGTGGC CACAGAAGCA CCCAAGAGGA AAACTGGCTA TTTTGCTGCC 2340

CCTACTCAGC TGGAGCCAGA GGATCAGTTT GTTGTACCTC GTGACCTGGA GGAAGAAGTG 2400

AAGGAGCAAA TGAAACAGCA TCAGGAAAGC AGGCCTGAGC CCGAGCCCAG TGAAGAGGAT 2460

CGGACCGAGC CCCCAGAGGA GTTTGACACA GCGCTATGA 2499

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 294   SHGLAEMAGQRNKLCVSSLAMDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  348

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + +++++Fl  +++l       ++ +k Gs+a++++i+++

Q: 349   LEEVQ----QSTNDTVFMTNTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpts  398

         ***99....77888889************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 399   sfSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDlEEARRVKDQKAIITEDN--KVNGVT  456

         *******************************999899********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++s++lt +de liL+   lw+++s  ea+++vr+v +

Q: 457   CCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNRALWEHLSYTEAINAVRHVQD--  514

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +a+kkL++la+++g++dnv a+vv

Q: 515   --PLAASKKLCTLAQSYGCQDNVGAMVV  540

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSSLA MDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMT NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPTSSFSLT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDL EEARRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISSTPLT IQDELLILGN RALWEHLSYT EAINAVRHVQ DPLAASKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>