EKS-ICT-00298

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00298

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	344.9	2.9E-103	12	262	251

Status

Unreviewed

Ensembl Protein

ENSSTOP00000020872

UniProt Accession

I3N926;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000022849	ENSSTOP00000020872	ENSSTOT00000019643

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

404

Protein Sequence
(FASTA)

MQNNIADPEE LFTKLERIGK GSFGEVFKGI DNRTQQVVAI KIIDLEEAED EIEDIQQEIT 60

VLSQCDSSYV TKYYGSYLKG SKLWIIMEYL GGGSALDLLR AGPFDEFQIA TMLKEILKGL 120

DYLHSEKKIH RDIKAANVLL SEQGDVKLAD FGVAGQLTDT QIKRNTFVGT PFWMAPEVIQ 180

QSAYDSKADI WSLGITAIEL AKGEPPNSDM HPMRVLFLIP KNNPPTLVGD FTKSFKEFID 240

ACLNKDPSFR PTAKELLKHK FIVKNSKKTS YLTELIDRFK RWKAEGHSDD ESDSDGSDSE 300

STSRENNAHP EWSFTTVRKK PDPKKLQNGA EQDLVQTLSC LSMIITPAFA ELKQQDENNA 360

SRNQAIEELE KSIAVAEAAC PGITDKMVKK LIEKFQKCSA DEST 404

Nucleotide Sequence
(FASTA)

ATGCAGAATA ATATAGCAGA TCCAGAAGAA CTGTTCACAA AATTAGAACG CATTGGAAAA 60

GGCTCATTTG GAGAAGTTTT CAAAGGAATT GATAACCGTA CTCAGCAAGT TGTTGCTATT 120

AAAATCATTG ACCTTGAGGA AGCCGAAGAT GAAATAGAAG ACATTCAACA AGAAATAACT 180

GTTTTGAGTC AATGTGACAG CTCATATGTA ACAAAATACT ATGGGTCATA TTTAAAGGGT 240

TCAAAATTAT GGATAATAAT GGAATACCTG GGTGGCGGTT CAGCACTGGA TCTTCTGCGA 300

GCTGGTCCAT TTGATGAGTT CCAGATCGCT ACCATGCTAA AGGAAATTTT GAAAGGTCTG 360

GACTATCTGC ATTCAGAAAA GAAAATTCAC CGAGACATAA AAGCTGCCAA TGTCCTGCTT 420

TCAGAACAAG GAGATGTTAA ACTTGCTGAC TTTGGAGTGG CTGGCCAGCT GACAGATACA 480

CAAATTAAAA GAAACACGTT TGTGGGAACT CCTTTTTGGA TGGCTCCTGA AGTTATTCAA 540

CAGTCAGCTT ATGACTCAAA AGCTGATATT TGGTCATTGG GAATTACTGC TATTGAACTA 600

GCCAAGGGAG AGCCGCCTAA TTCTGATATG CATCCAATGA GAGTTTTGTT TCTTATTCCA 660

AAAAACAATC CTCCAACTCT TGTTGGAGAC TTTACTAAGT CTTTTAAGGA GTTTATTGAT 720

GCTTGCCTGA ATAAAGATCC ATCATTTCGC CCTACAGCTA AAGAACTTCT GAAACATAAA 780

TTCATTGTAA AAAATTCCAA GAAGACTTCT TATCTGACTG AACTGATCGA TCGATTTAAG 840

AGATGGAAGG CAGAAGGACA CAGTGATGAT GAATCTGATT CTGATGGCTC TGATTCGGAA 900

TCCACCAGCA GGGAAAACAA TGCTCATCCT GAATGGAGTT TTACCACTGT GCGAAAGAAG 960

CCTGATCCAA AGAAACTACA GAATGGAGCA GAGCAAGATC TTGTGCAAAC TCTGAGCTGT 1020

TTGTCTATGA TAATCACACC TGCATTTGCT GAACTTAAAC AGCAGGATGA GAATAATGCA 1080

AGCAGGAATC AGGCAATTGA AGAACTTGAG AAAAGTATTG CTGTGGCTGA AGCTGCCTGT 1140

CCTGGCATCA CTGACAAAAT GGTGAAGAAA TTAATTGAAA AGTTTCAAAA GTGTTCTGCA 1200

GATGAATCCA CCTAA 1215

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         ++ le+igkG++g+v+++ +++t+++vaik+i+le+  +++e++q+ei+vl+++++++++

Q: 12    FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAeDEIEDIQQEITVLSQCDSSYVT  71

         7889*******************************99899********************

S: 60    eylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkv  119

         +y++s+lk ++lw++meyl gGs+ dl++     +++E qia++l+e+lk+L+ylHs+k+

Q: 72    KYYGSYLKGSKLWIIMEYLGGGSALDLLR---AGPFDEFQIATMLKEILKGLDYLHSEKK  128

         *****************************...****************************

S: 120   iHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYde  179

         iHrdika+n+Ll+e+g+VkL+dfgva ql++t+ kr+t+vgtp+wmAPEvi+  ++ Yd+

Q: 129   IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQ--QSAYDS  186

         ****************************************************..9*****

S: 180   kaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclq  239

         kaDiwslGItaiela+gepP +d++p+++l++i+kn+pp+l  +  f+k+fkef+++cl+

Q: 187   KADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGD--FTKSFKEFIDACLN  244

         *****************************************777..**************

S: 240   knpekRpsasellkhkFl  257

         k+p++Rp+a+ellkhkF+

Q: 245   KDPSFRPTAKELLKHKFI  262

         *****************7

Domain Sequence
(FASTA)

FTKLERIGKG SFGEVFKGID NRTQQVVAIK IIDLEEAEDE IEDIQQEITV LSQCDSSYVT 60

KYYGSYLKGS KLWIIMEYLG GGSALDLLRA GPFDEFQIAT MLKEILKGLD YLHSEKKIHR 120

DIKAANVLLS EQGDVKLADF GVAGQLTDTQ IKRNTFVGTP FWMAPEVIQQ SAYDSKADIW 180

SLGITAIELA KGEPPNSDMH PMRVLFLIPK NNPPTLVGDF TKSFKEFIDA CLNKDPSFRP 240

TAKELLKHKF I 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013