EKS-ICT-00151

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00151

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSK	309.5	2.1E-92	6	224	219

Status

Unreviewed

Ensembl Protein

ENSSTOP00000020739

UniProt Accession

I3N8P3;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KB1

Gene Synonyms/Alias

RPS6KB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000026687	ENSSTOP00000020739	ENSSTOT00000020882

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

397

Protein Sequence
(FASTA)

MIVRNAKDTA HTKAERNILE EVKHPFIVDL IYAFQTGGKL YLILEYLSGG ELFMQLEREG 60

IFMEDTACFY LAEISMALGH LHQKGIIYRD LKPENIMLNH QGHVKLTDFG LCKESIHDGT 120

VTHTFCGTIE YMAPEILMRS GHNRAVDWWS LGALMYDMLT GAPPFTGENR KKTIDKILKC 180

KLNLPPYLTQ EARDLLKKLL KRNAASRLGA GPGDAGEVQA HPFFRHINWE ELLARKVEPP 240

FKPLLQSEED VSQFDSKFTR QTPVDSPDDS TLSESANQVF LGFTYVAPSV LESVKEKFSF 300

EPKIRSPRRF IGSPRTPVSP VKFSPGDFWA RGASASTANP QTPVEYPMET SGIEQMDVTM 360

SGEASAPLPI RQPNSGPYKK QAFPMISKRP EHLRMNL 397

Nucleotide Sequence
(FASTA)

ATGATAGTAA GAAATGCTAA AGATACAGCT CATACAAAAG CAGAACGGAA TATTCTGGAG 60

GAAGTAAAGC ATCCCTTCAT TGTGGATTTA ATTTATGCCT TTCAGACCGG TGGAAAACTC 120

TACCTCATCC TTGAGTATCT CAGTGGAGGA GAACTATTTA TGCAGTTAGA AAGAGAGGGA 180

ATATTTATGG AAGACACAGC TTGCTTTTAC TTGGCAGAAA TCTCCATGGC TTTGGGGCAT 240

TTACATCAAA AGGGAATCAT CTACAGAGAC CTGAAGCCGG AGAACATCAT GCTTAATCAC 300

CAAGGTCATG TGAAATTAAC AGACTTTGGA CTATGCAAAG AATCTATTCA TGATGGAACA 360

GTCACACACA CATTTTGTGG AACAATAGAA TACATGGCCC CTGAAATCTT GATGAGAAGT 420

GGCCACAATC GTGCTGTGGA TTGGTGGAGT TTGGGAGCAT TAATGTATGA CATGCTGACT 480

GGAGCACCTC CATTCACTGG GGAAAATAGA AAGAAAACAA TTGACAAAAT CCTCAAATGT 540

AAACTCAATT TGCCTCCCTA CCTCACACAA GAAGCCAGAG ATTTGCTTAA AAAGCTGCTG 600

AAAAGAAATG CTGCTTCTCG ACTTGGAGCT GGTCCTGGGG ACGCTGGAGA AGTTCAAGCT 660

CATCCATTCT TCCGACATAT TAATTGGGAA GAACTTCTGG CTCGGAAGGT GGAGCCTCCC 720

TTTAAACCTC TGTTGCAATC CGAAGAGGAT GTGAGTCAGT TTGATTCGAA GTTTACACGT 780

CAGACACCTG TTGACAGCCC AGATGACTCA ACTCTCAGTG AAAGTGCCAA CCAGGTCTTT 840

CTGGGTTTTA CATATGTGGC TCCATCTGTA CTTGAAAGTG TGAAAGAAAA GTTTTCCTTT 900

GAACCAAAAA TTCGATCTCC ACGAAGATTT ATTGGCAGCC CACGAACACC TGTCAGCCCC 960

GTCAAATTTT CTCCTGGGGA TTTCTGGGCA AGAGGTGCTT CAGCCAGCAC AGCAAATCCT 1020

CAGACGCCTG TGGAATACCC AATGGAAACA AGTGGAATAG AGCAGATGGA TGTGACAATG 1080

AGTGGGGAAG CGTCAGCACC ACTTCCAATA CGACAGCCGA ACTCCGGGCC ATACAAAAAA 1140

CAAGCTTTTC CCATGATCTC CAAACGGCCA GAGCACCTGC GAATGAATCT ATGA 1194

Domain Profile

S: 42    kkkkertkeereiLeevehpfivklheafqdekklylvlellkGgeLlerlkkkklfsee  101

         +k++++tk+er+iLeev+hpfiv+l +afq+  klyl+le+l+GgeL+++l+++++f+e+

Q: 6     AKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMED  65

         3999********************************************************

S: 102   easfilaelvlaleylHskgvvyrDLkpeNilldeeghvkltDfglakekiaeneekays  161

         +a+f+lae+++al +lH+kg++yrDLkpeNi+l+++ghvkltDfgl+ke+i ++++ +++

Q: 66    TACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESI-HDGTVTHT  124

         **************************************************9.9999999*

S: 162   fcgTleyvaPevlkrkgydeavDlwslGvllyemLtGktPftgeerketlarilkgkfsl  221

         fcgT+ey+aPe+l+r+g+++avD+wslG+l+y+mLtG++Pftge+rk+t+++ilk+k  l

Q: 125   FCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK--L  182

         *********************************************************..9

S: 222   klpaweelseeakdlvkklLkkdpakRlga...taeeikehkfl  262

         +lp +  l++ea+dl+kklLk++ a+Rlga   +a e+++h+f+

Q: 183   NLPPY--LTQEARDLLKKLLKRNAASRLGAgpgDAGEVQAHPFF  224

         *****..***********************9*9*********97

Domain Sequence
(FASTA)

AKDTAHTKAE RNILEEVKHP FIVDLIYAFQ TGGKLYLILE YLSGGELFMQ LEREGIFMED 60

TACFYLAEIS MALGHLHQKG IIYRDLKPEN IMLNHQGHVK LTDFGLCKES IHDGTVTHTF 120

CGTIEYMAPE ILMRSGHNRA VDWWSLGALM YDMLTGAPPF TGENRKKTID KILKCKLNLP 180

PYLTQEARDL LKKLLKRNAA SRLGAGPGDA GEVQAHPFF 219

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013