EKS-ICT-00416

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ICT-00416

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	363.5	7.0E-109	3	259	257

Status

Unreviewed

Ensembl Protein

ENSSTOP00000021319

UniProt Accession

I3NAC2;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK3

Gene Synonyms/Alias

ULK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSSTOG00000028194	ENSSTOP00000021319	ENSSTOT00000020607

Organism

Ictidomys tridecemlineatus

Functional Description

Protein Length

461

Protein Sequence
(FASTA)

DGFILTERLG SGTYATVYKA YAKKDTREVV AIKCVAKKSL NKASVENLLT EIEILKGIRH 60

PHIVQLKDFQ WDSDNIYLIM EFCAGGDLSR FIHTRRILPE KVARVFMQQL ASALQFLHER 120

NISHLDLKPQ NILLSSLEKP HLKLADFGFA QHMSPWDEKH VLRGSPLYMA PEMVCQRQYD 180

ARVDLWSVGV ILYEALFGQP PFASRSFLEL EEKIRSNRVI ELPLRPPLSR DCRDLLQRLL 240

ERDPSRRISF QDFFAHPWVD LEHMPSGESL ARASALVVEA VKKDQEGDAA TALSLYCKAL 300

DFFVPALHYE VDAQRKEAIK AKVGQYVSRA EELKAIVSSS NKALLRQGTS ARDLLREMAR 360

DKPRLLAALE VASAAMAKEE EANGEQDALD LYQHSLGELL LLLAAEPPGR RRELLHTEVQ 420

NLMARAEYLK EQVKMRESRW EGETLDKEGL SESVRSSCTL Q 461

Nucleotide Sequence
(FASTA)

GACGGCTTCA TCCTCACCGA GCGCCTGGGC AGTGGCACCT ACGCCACCGT GTACAAGGCC 60

TACGCCAAGA AGGACACTCG AGAGGTGGTA GCTATAAAGT GTGTGGCAAA AAAAAGTCTG 120

AACAAGGCGT CGGTGGAAAA CCTCCTGACT GAGATTGAGA TCCTCAAGGG CATTCGGCAC 180

CCCCATATCG TGCAGCTGAA AGACTTCCAG TGGGACAGTG ACAATATCTA CCTCATCATG 240

GAGTTCTGTG CGGGAGGTGA CTTGTCTCGA TTCATTCATA CTCGAAGGAT TCTTCCTGAG 300

AAGGTGGCTC GAGTCTTCAT GCAGCAATTG GCTAGTGCCC TGCAGTTTCT GCATGAACGA 360

AACATCTCTC ACCTGGATCT GAAGCCACAG AACATTCTGC TGAGTTCTTT GGAGAAGCCC 420

CACCTTAAAC TGGCAGACTT TGGCTTCGCA CAGCACATGT CCCCATGGGA TGAGAAGCAT 480

GTACTCCGCG GTTCTCCCCT CTATATGGCC CCTGAGATGG TGTGTCAGCG ACAGTACGAC 540

GCCCGTGTGG ACCTTTGGTC CGTAGGGGTC ATCCTGTATG AAGCCCTCTT TGGGCAGCCC 600

CCTTTTGCCT CCAGGTCATT CTTGGAACTG GAAGAGAAGA TCCGAAGCAA TCGGGTTATT 660

GAGCTCCCCT TGAGGCCCCC GCTCTCCCGA GACTGCCGTG ACCTACTACA GCGGCTCCTG 720

GAGCGGGACC CAAGCCGTCG GATCTCCTTC CAGGACTTCT TTGCCCACCC CTGGGTAGAC 780

CTGGAGCACA TGCCTAGTGG GGAGAGCTTG GCACGAGCAA GTGCCCTGGT GGTAGAGGCT 840

GTAAAGAAGG ACCAGGAAGG GGACGCTGCG ACTGCCTTAT CTCTCTACTG CAAGGCTCTG 900

GACTTCTTTG TGCCTGCCCT GCATTATGAA GTGGATGCCC AGCGGAAGGA AGCAATTAAG 960

GCAAAGGTAG GGCAGTACGT GTCCCGGGCT GAGGAGCTCA AGGCCATCGT CTCCTCCTCC 1020

AACAAGGCCC TGCTGAGACA GGGAACATCA GCCAGAGACC TGCTGAGAGA GATGGCCCGG 1080

GACAAGCCAC GCCTCCTAGC TGCCCTGGAA GTGGCTTCGG CTGCCATGGC CAAGGAAGAA 1140

GAAGCCAATG GAGAGCAGGA TGCCTTGGAC CTGTACCAAC ACAGCCTGGG GGAGCTGCTG 1200

CTGCTGCTGG CAGCGGAGCC CCCAGGCCGA AGGCGAGAAT TGCTTCACAC TGAGGTTCAG 1260

AACCTCATGG CTCGGGCTGA ATACCTGAAG GAGCAGGTCA AGATGAGGGA ATCTCGCTGG 1320

GAAGGAGAGA CCCTGGACAA GGAGGGGCTG TCGGAGTCAG TTCGTAGCTC TTGCACCTTA 1380

CAGTGA 1386

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         ++l+e++G+G++a+vyk++++k+t++vvAik+v+kk+l k+s+enl +ei+ilk ++h++

Q: 3     FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLnKASVENLLTEIEILKGIRHPH  62

         7899**********************************999*******************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv+l+d++++s+++yl+me+caggdL++++++++ L+e+++r+f+qqlasal++Lh+++i

Q: 63    IVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNI  122

         ************************************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         +h DlkPqniLls      +l+k +lkladFg+a++++ +++++ l+GsplYmaPE+v++

Q: 123   SHLDLKPQNILLS------SLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQ  176

         *************......89***************************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

         +qyda++DlWS+G+ilye+l+G+pPfa++s++eL+eki++n+v+e+p++  +s++++dll

Q: 177   RQYDARVDLWSVGVILYEALFGQPPFASRSFLELEEKIRSNRVIELPLRPPLSRDCRDLL  236

         ************************************************************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

         q+LL+rdp++Risf+++fahp++

Q: 237   QRLLERDPSRRISFQDFFAHPWV  259

         *********************96

Domain Sequence
(FASTA)

FILTERLGSG TYATVYKAYA KKDTREVVAI KCVAKKSLNK ASVENLLTEI EILKGIRHPH 60

IVQLKDFQWD SDNIYLIMEF CAGGDLSRFI HTRRILPEKV ARVFMQQLAS ALQFLHERNI 120

SHLDLKPQNI LLSSLEKPHL KLADFGFAQH MSPWDEKHVL RGSPLYMAPE MVCQRQYDAR 180

VDLWSVGVIL YEALFGQPPF ASRSFLELEE KIRSNRVIEL PLRPPLSRDC RDLLQRLLER 240

DPSRRISFQD FFAHPWV 257

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF04212	; MIT; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00745	; MIT; 2.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013