EKS-TUB-00021

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TUB-00021

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	430.5	3.0E-129	64	359	296

Status

Unreviewed

Ensembl Protein

ENSTBEP00000005485

Gene Name

DYRK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTBEG00000006370	ENSTBEP00000005485	ENSTBET00000006367

Organism

Tupaia belangeri

Protein Length

399

Protein Sequence
(FASTA)

ALKLFKDQLS PYEQSEILGY TELWFLGLDA EKLNVTPEKF SKTSFDDEHG SYMKVLHDHI 60

AYRYEVLEMI GKGSFGQVPK CLDHKNNELV ALKIIRNKKR FHHQALVELK ILEALRRKDK 120

DNTHNVVHMK DFFYFRNHLC ITFELLGINL YELMKNNSFQ GFSLSIVRRF TLSVLKCLQM 180

LYVEKIIHCD LKPENIVLYQ KGQVSVKVID FGSSCYDHQK VYTYIQSRFY RSPEVILGHP 240

YNMAIDMWSL GCIMAELYTG YPLFPGENEV EQLACIMEVL GLPPTRFIQT ASRRQTFFDS 300

KGPKNITNNR GKKRYPDSKD LTTVLKTYDS SFLDFLRRCL VWEPSLRMTP DQALKHAWIH 360

EPRSLKPRPR PQILRKTSFC FPSDKRKDKY SGYHHASKK 399

Nucleotide Sequence
(FASTA)

GCCCTAAAGC TTTTTAAGGA TCAGCTGTCT CCTTATGAGC AAAGTGAAAT CCTGGGCTAC 60

ACAGAGCTGT GGTTCCTGGG ACTTGATGCT GAGAAGCTCA ACGTGACTCC TGAGAAATTC 120

AGCAAGACAA GTTTCGACGA CGAACATGGA TCCTATATGA AGGTCCTGCA TGACCACATT 180

GCCTACCGCT ACGAGGTTCT GGAGATGATC GGAAAAGGGT CTTTTGGACA GGTGCCCAAG 240

TGCTTGGATC ACAAAAACAA TGAATTGGTG GCCCTGAAAA TCATCAGGAA CAAGAAGAGA 300

TTTCACCATC AGGCCCTGGT GGAGCTCAAG ATCCTGGAAG CGCTCAGAAG GAAGGACAAA 360

GACAACACCC ACAACGTGGT GCACATGAAG GACTTTTTCT ACTTCCGCAA TCACCTCTGT 420

ATCACCTTTG AACTCCTGGG AATCAACTTG TATGAGTTGA TGAAGAATAA TAGCTTTCAA 480

GGCTTCAGTC TGTCAATAGT TCGGCGCTTC ACACTCTCTG TTTTAAAGTG CTTGCAAATG 540

CTCTATGTAG AGAAAATCAT TCACTGTGAC CTCAAACCTG AAAATATAGT GCTGTACCAA 600

AAGGGTCAAG TCTCTGTTAA AGTTATTGAC TTTGGATCTA GCTGTTATGA TCACCAGAAA 660

GTATACACCT ACATCCAAAG CCGCTTCTAC CGATCCCCAG AGGTGATTCT GGGCCACCCC 720

TACAACATGG CCATTGATAT GTGGAGCTTG GGCTGCATCA TGGCGGAGCT GTACACGGGC 780

TACCCCCTGT TCCCCGGGGA GAATGAAGTG GAGCAGCTGG CTTGCATCAT GGAGGTGCTG 840

GGCCTACCAC CAACCCGCTT CATTCAGACG GCCTCTAGGA GACAGACGTT CTTTGATTCC 900

AAAGGTCCTA AAAATATAAC CAACAACAGG GGGAAAAAAA GATACCCGGA TTCCAAGGAT 960

CTCACGACGG TGCTGAAAAC CTATGACTCA AGCTTCCTGG ACTTTCTCAG AAGGTGTCTG 1020

GTATGGGAAC CTTCTCTTCG AATGACCCCA GACCAGGCCC TCAAGCATGC TTGGATTCAT 1080

GAGCCACGAA GCCTCAAACC ACGGCCCAGA CCCCAGATTT TGAGGAAAAC CAGTTTCTGT 1140

TTCCCCTCTG ACAAAAGGAA GGACAAGTAT TCAGGGTACC ATCATGCAAG CAAAAAA 1197

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevle+igkGsfgqV k+ld+k++e va+kii+nkkrf++qa  E++iLe+l++kdk+++

Q: 64    YEVLEMIGKGSFGQVPKCLDHKNNELVALKIIRNKKRFHHQALVELKILEALRRKDKDNT  123

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         +nvv+++++f+frnhlc++fell +nLyel+k+n+f+g+sl++vr+++ ++lk+L++L+

Q: 124   HNVVHMKDFFYFRNHLCITFELLGINLYELMKNNSFQGFSLSIVRRFTLSVLKCLQMLYV  183

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglkyd  180

         +kiiH+DlKPeNi+l++k++ +vkviDFGss++ +qk +ytyiqsrfYr+PE+ilg++y+

Q: 184   EKIIHCDLKPENIVLYQKGQVSVKVIDFGSSCYDHQK-VYTYIQSRFYRSPEVILGHPYN  242

         *************************************.**********************

S: 181   eaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftkke  240

         +aiDmWSlGc++aEl+tG+pLfpGenev+qla+i+evlglpp++++++a+++++ff++k+

Q: 243   MAIDMWSLGCIMAELYTGYPLFPGENEVEQLACIMEVLGLPPTRFIQTASRRQTFFDSKG  302

         ********************************************************7766

S: 241   apkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedklfkdllkrmleldp  300

          ++                 ++++  k+++p sk+l+++lk+++++ f d+l+r+l ++p

Q: 303   PKN-----------------ITNNRGKKRYPDSKDLTTVLKTYDSS-FLDFLRRCLVWEP  344

         543.................33444567899*********999877.*************

S: 301   akRitpkealkhpfv  315

         + R+tp++alkh ++

Q: 345   SLRMTPDQALKHAWI  359

         *************97

Domain Sequence
(FASTA)

YEVLEMIGKG SFGQVPKCLD HKNNELVALK IIRNKKRFHH QALVELKILE ALRRKDKDNT 60

HNVVHMKDFF YFRNHLCITF ELLGINLYEL MKNNSFQGFS LSIVRRFTLS VLKCLQMLYV 120

EKIIHCDLKP ENIVLYQKGQ VSVKVIDFGS SCYDHQKVYT YIQSRFYRSP EVILGHPYNM 180

AIDMWSLGCI MAELYTGYPL FPGENEVEQL ACIMEVLGLP PTRFIQTASR RQTFFDSKGP 240

KNITNNRGKK RYPDSKDLTT VLKTYDSSFL DFLRRCLVWE PSLRMTPDQA LKHAWI 296

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>