EKS-TAG-00147

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00147

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	356.2	1.0E-106	40	312	273

Status

Unreviewed

Ensembl Protein

ENSTGUP00000000169

UniProt Accession

H0YPH1;

Protein Name

Protein Synonyms/Alias

Gene Name

GAK

Gene Synonyms/Alias

GAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000000154	ENSTGUP00000000169	ENSTGUT00000000172

Organism

Taeniopygia guttata

Functional Description

Protein Length

1278

Protein Sequence
(FASTA)

MSLFQSALDF LAGPGSLGAA SRDQNDFVGQ TVEMGDMKLR IKRVIAEGGF AFVYEAQDLG 60

SGKDYALKRL LSNEEEKNKA IIQEVCFMKK LSGHPNIVQF CSAASIGKEE SDTGQGEFLL 120

LTELCKGQLV EFLKKVESKG PISCDTVLKI FYQTCRAVQH MHKQKPPIIH RDLKVENLLI 180

SNQGTIKLCD FGSATTIAYY PDYNWSAQKR AVVEEEITRN TTPMYRTPEM IDLYSNFPIG 240

EKQDIWALGC ILYLLCFRQH PFEDGAKLRI VNGKYVIPQN DTRYSVFHDL IRSTLKVNPE 300

ERLSITELVN QLQEIAAARN VNPKSPITEL LEQNGGYGNN AQPRTSSSKP AGQLNNLYNA 360

GLTVAECDQT YGGFFDILRG GTERFFTNIK DTSSKVIQSV AKSGEKKEEV LQAFNSASEN 420

HCVVFLLCIA LYFESLLYLT VSECGWPARR APNLQNLYSI CKNMHLWLKQ DQKNVCIVHC 480

LDGRAASAVV VCSFLCFCRL FTTAEAAVYM FSMKRCPPGI WPSHKRYIEY MCDMMAEEPI 540

IPHSKPILVR SIVMTPVPLF SKQRNGCRPF CEIYVGDERV TTTSQEYDKM KEFKIEDGKA 600

VIPLGITVQG DVLIVIYHAR STLGGRLQAK MASMKMFQIQ FHTGFVPRNA TTVKFAKYDL 660

DACDIQEKYP DLFQVNLEVE VEPRDRPSCE QPPWDNMNIK GLNPKILFST REEQQEILSK 720

FGKPELPRQP GSTAQYEAEA SQLEHAPTDT ESPHSGSTDA NNFFQSLDWK EGKSPESGIE 780

DGSSKNDCVQ VSDDREESDP SDEEFPTFPD EGSAVIVDEK DSTPEGELLF EASFEAPSAP 840

LQKSLPEENV DLLGLDSDIS VEQKQPISEI NSSSSNADLL NNLFVSSVSQ VSNEPTGDLL 900

GQGTDFFFSS QHPAATQGSS SAAAVSSADP FDPFTMSSSS ENQALSGPDL FGDFLNPTST 960

STVNTVHSTQ SSLPPSSSSD FLNLGNLTPE PSKISTSTSH PDLLSGWDSW ADSSTTSNVA 1020

APQLKPVSFT TGSQSSVSSG LSFSQAKAQN FDPFADLANL GSGLPGSSAG GLLGSGFSQK 1080

TAPSQKLGSQ WQKSSKPQST SWQSQTKSST AAKPNYTVNF SVIGGREERG VRAPGFGQKP 1140

KVSENDFEDL LSNQGFSAKS DKKGPKTIAE MRKQEMSKDM DPLKLKILEW IEGKERNIRA 1200

LISTLHTVLW EGENKWKPVS MADLVTPEQV KKYYRKAVLV VHPDKATGQP YEQYAKMIFM 1260

ELNDAWSEFE NQGSKSLF 1278

Nucleotide Sequence
(FASTA)

ATGTCGCTGT TCCAATCCGC CCTGGACTTC CTGGCGGGCC CCGGCTCCCT GGGAGCCGCC 60

AGCCGTGACC AGAACGATTT CGTGGGGCAG ACGGTGGAGA TGGGCGACAT GAAGCTGCGC 120

ATCAAGCGGG TCATCGCCGA GGGGGGTTTT GCTTTTGTCT ATGAAGCTCA AGATCTTGGA 180

AGTGGCAAAG ATTATGCTTT GAAGCGATTG TTGTCTAATG AAGAGGAAAA GAACAAAGCT 240

ATCATTCAGG AAGTTTGTTT CATGAAAAAA CTTTCAGGTC ATCCCAACAT TGTCCAGTTT 300

TGCTCTGCAG CATCTATAGG AAAAGAAGAA TCAGACACGG GGCAGGGAGA GTTTCTTCTG 360

CTTACAGAGC TGTGTAAAGG ACAGCTTGTG GAATTCTTAA AGAAAGTAGA ATCCAAAGGA 420

CCTATCTCTT GTGACACAGT TTTGAAGATC TTTTATCAGA CATGCAGAGC AGTGCAGCAT 480

ATGCATAAGC AGAAGCCTCC TATTATTCAT AGAGACTTAA AGGTGGAAAA TTTGCTTATT 540

AGTAATCAGG GGACAATTAA GCTTTGTGAC TTCGGTAGTG CTACAACTAT AGCTTACTAT 600

CCTGACTACA ACTGGTCTGC ACAGAAGAGA GCAGTGGTTG AAGAAGAGAT CACAAGGAAT 660

ACAACACCAA TGTACAGGAC ACCAGAAATG ATAGACTTGT ATTCAAATTT CCCAATTGGT 720

GAAAAGCAGG ACATTTGGGC TCTGGGCTGT ATCCTGTACT TGCTGTGCTT TAGGCAACAC 780

CCATTTGAAG ATGGAGCTAA ACTTCGCATA GTCAATGGGA AATATGTCAT CCCACAAAAT 840

GACACTCGCT ACTCTGTGTT TCATGATCTC ATTCGCTCCA CTTTGAAAGT GAACCCAGAG 900

GAGAGATTGT CAATCACTGA ACTTGTGAAC CAACTGCAGG AGATTGCAGC AGCTAGGAAT 960

GTCAATCCTA AATCCCCTAT CACAGAGCTC CTGGAGCAAA ATGGAGGCTA TGGAAACAAT 1020

GCTCAGCCTC GGACATCTAG CTCCAAGCCT GCAGGGCAGC TCAACAACTT GTACAATGCA 1080

GGCCTGACCG TTGCGGAATG TGACCAGACT TATGGAGGGT TCTTTGATAT TCTGAGAGGT 1140

GGAACAGAGC GATTTTTCAC TAATATTAAG GACACATCTT CTAAAGTTAT CCAGTCTGTG 1200

GCCAAGAGTG GGGAAAAAAA AGAGGAAGTG CTCCAAGCAT TTAATTCTGC TAGTGAGAAT 1260

CATTGTGTAG TTTTCCTTCT TTGTATTGCC TTATATTTTG AATCCTTACT GTATTTAACA 1320

GTTTCTGAAT GTGGCTGGCC AGCAAGACGA GCACCAAATC TTCAGAATCT CTATAGCATA 1380

TGCAAGAACA TGCATTTATG GCTGAAACAA GACCAGAAAA ATGTTTGCAT TGTGCATTGC 1440

CTTGATGGAA GAGCAGCATC TGCTGTTGTA GTCTGTTCTT TTCTGTGTTT TTGTCGTCTC 1500

TTCACTACTG CTGAAGCTGC TGTTTATATG TTCAGTATGA AACGCTGCCC ACCTGGCATT 1560

TGGCCTTCTC ATAAAAGATA CATTGAGTAC ATGTGTGACA TGATGGCTGA AGAACCCATT 1620

ATCCCTCACA GCAAGCCCAT CCTGGTCAGA TCAATTGTCA TGACTCCCGT TCCACTTTTC 1680

AGTAAGCAGC GTAACGGCTG CAGGCCTTTT TGTGAGATTT ATGTGGGAGA TGAGAGAGTA 1740

ACCACCACCT CCCAGGAATA TGACAAAATG AAGGAGTTTA AAATTGAAGA TGGGAAAGCA 1800

GTAATCCCAT TGGGTATAAC AGTCCAAGGG GATGTTCTCA TTGTGATCTA TCATGCCAGG 1860

TCAACTCTAG GAGGACGACT ACAAGCCAAG ATGGCTTCAA TGAAGATGTT TCAGATTCAG 1920

TTCCATACAG GCTTTGTGCC CCGAAATGCT ACTACAGTGA AATTTGCCAA ATATGATCTG 1980

GATGCCTGTG ACATACAAGA GAAATACCCT GATTTATTTC AAGTCAATCT GGAAGTAGAG 2040

GTGGAGCCCA GAGATAGGCC CAGCTGTGAG CAGCCACCTT GGGATAACAT GAATATAAAG 2100

GGTCTGAATC CCAAGATCCT CTTCTCCACC CGAGAGGAAC AGCAAGAGAT TTTATCAAAA 2160

TTTGGAAAAC CAGAGTTGCC TAGACAGCCA GGTTCAACTG CACAATACGA GGCAGAGGCA 2220

TCCCAGCTGG AGCATGCACC TACTGATACA GAATCCCCAC ACAGTGGTAG TACTGATGCA 2280

AACAACTTCT TTCAGTCTCT GGACTGGAAA GAAGGAAAAT CTCCAGAAAG TGGAATAGAG 2340

GATGGTTCAT CTAAAAATGA TTGTGTTCAG GTGTCTGATG ACAGGGAAGA GAGTGATCCT 2400

TCAGATGAGG AGTTCCCAAC ATTTCCAGAT GAAGGAAGTG CAGTAATTGT TGATGAGAAA 2460

GACTCTACTC CAGAAGGAGA GTTGCTTTTT GAAGCCAGTT TTGAAGCTCC ATCTGCACCG 2520

TTACAAAAAT CTCTCCCTGA AGAGAATGTG GACTTGCTGG GACTAGACTC TGATATTTCA 2580

GTAGAACAGA AACAGCCTAT CTCAGAAATA AACTCTTCAT CAAGTAATGC TGACTTGTTG 2640

AACAATCTGT TTGTGAGTAG TGTGTCACAG GTTTCAAATG AGCCCACTGG AGATCTTCTT 2700

GGACAAGGAA CAGATTTCTT TTTCAGCAGT CAGCATCCAG CTGCTACTCA GGGTTCATCT 2760

TCAGCAGCAG CTGTGTCTTC AGCCGATCCA TTTGACCCAT TCACAATGTC ATCAAGCTCA 2820

GAGAATCAAG CCCTGTCTGG TCCAGACCTC TTTGGGGACT TCCTTAATCC AACCTCAACA 2880

TCTACAGTTA ATACAGTTCA TTCCACACAA AGTTCACTTC CACCTTCTTC CAGCTCAGAT 2940

TTCCTAAATT TAGGCAATTT GACACCAGAG CCATCTAAAA TATCAACATC TACAAGCCAC 3000

CCAGACCTCT TAAGTGGATG GGATTCTTGG GCGGATTCCT CAACAACCAG CAATGTAGCA 3060

GCACCACAGC TGAAGCCTGT TTCTTTTACC ACTGGAAGCC AGTCCAGTGT GTCTTCAGGT 3120

TTGTCTTTTA GCCAGGCAAA AGCTCAGAAC TTCGATCCTT TTGCTGATCT TGCCAATCTG 3180

GGATCTGGTC TTCCAGGTTC ATCCGCTGGT GGACTCTTGG GTAGTGGATT TAGTCAGAAG 3240

ACTGCTCCAT CTCAGAAGCT GGGAAGTCAG TGGCAGAAAT CCTCCAAACC ACAAAGTACT 3300

TCATGGCAGT CCCAGACTAA GTCCAGCACT GCAGCTAAGC CAAACTACAC AGTAAACTTC 3360

AGTGTAATTG GAGGACGAGA AGAGAGAGGA GTCAGAGCCC CAGGCTTTGG TCAAAAGCCA 3420

AAAGTTTCAG AAAATGACTT TGAGGATCTC TTATCTAATC AAGGATTTTC AGCGAAATCT 3480

GATAAAAAGG GACCAAAGAC AATTGCTGAG ATGAGAAAAC AAGAGATGTC TAAAGATATG 3540

GACCCCTTGA AACTCAAGAT TCTTGAATGG ATTGAAGGAA AGGAGAGAAA TATCAGAGCA 3600

TTAATATCCA CTCTACATAC AGTGCTTTGG GAAGGGGAAA ATAAGTGGAA GCCAGTCAGC 3660

ATGGCAGATT TAGTAACTCC TGAACAAGTG AAGAAGTACT ACAGGAAAGC AGTGCTTGTG 3720

GTTCATCCTG ATAAGGCCAC AGGACAACCT TACGAGCAAT ATGCCAAAAT GATCTTCATG 3780

GAATTGAATG ATGCATGGTC AGAGTTCGAA AACCAGGGAT CAAAGTCCCT TTTCTGA 3837

Domain Profile

S: 2     riekvlaeGGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghknivk  61

         ri++v+aeGGfa+vy a+d+ +g+ yalKr+l+neee++++i++E+++mkklsgh+niv+

Q: 40    RIKRVIAEGGFAFVYEAQDLGSGKDYALKRLLSNEEEKNKAIIQEVCFMKKLSGHPNIVQ  99

         89**********************************************************

S: 62    lv..dssvkeekdngskevlllleyckkgslvdllnkrlekgelseaeilkilldvtrav  119

         ++  +s  kee+d+g+ e+lll+e+ck g+lv++l+k ++kg +s++++lki+++++rav

Q: 100   FCsaASIGKEESDTGQGEFLLLTELCK-GQLVEFLKKVESKGPISCDTVLKIFYQTCRAV  158

         **777888999****************.8*******************************

S: 120   aalHalsvpliHRDlkveNillsdegelvlcDlGSattaileve...skqelsalqeeie  176

         +++H++++p+iHRDlkveN+l+s++g+++lcD+GSatt+   ++   s+q++++++eei+

Q: 159   QHMHKQKPPIIHRDLKVENLLISNQGTIKLCDFGSATTIAYYPDynwSAQKRAVVEEEIT  218

         *******************************************99999************

S: 177   knttlsyrsPElidlysnlvideksDiWaLGcllYklcffesPfeesvklailngkysiP  236

         +ntt++yr+PE+idlysn++i+ek+DiWaLGc+lY lcf+++Pfe+++kl+i+ngky iP

Q: 219   RNTTPMYRTPEMIDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIP  278

         ************************************************************

S: 237   ensryseklkslikkmlevdpeeRptiaqvlell  270

         +n++ ++ +++li++ l+v+peeR++i++++++l

Q: 279   QNDTRYSVFHDLIRSTLKVNPEERLSITELVNQL  312

         ******************************9986

Domain Sequence
(FASTA)

RIKRVIAEGG FAFVYEAQDL GSGKDYALKR LLSNEEEKNK AIIQEVCFMK KLSGHPNIVQ 60

FCSAASIGKE ESDTGQGEFL LLTELCKGQL VEFLKKVESK GPISCDTVLK IFYQTCRAVQ 120

HMHKQKPPII HRDLKVENLL ISNQGTIKLC DFGSATTIAY YPDYNWSAQK RAVVEEEITR 180

NTTPMYRTPE MIDLYSNFPI GEKQDIWALG CILYLLCFRQ HPFEDGAKLR IVNGKYVIPQ 240

NDTRYSVFHD LIRSTLKVNP EERLSITELV NQL 273

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005794	; C:Golgi apparatus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR001623	; DnaJ_N.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00226	; DnaJ; 1.
PF00069	; Pkinase; 1.
PF10409	; PTEN_C2; 1.

SMARTs

SM00271

; DnaJ; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS50076	; DNAJ_2; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013