EKS-TAG-00041
Eukaryotic Protein Kinase & Protein Phosphatase Database
TagContent
EKPD IDEKS-TAG-00041
Classification
Group/FamilyScoreE-ValueStartEndDomain Length
AGC/GRK464.87.6E-140169432264
StatusUnreviewed
Ensembl ProteinENSTGUP00000000413
UniProt AccessionH0YQ60;
Protein Name
Protein Synonyms/Alias
Gene NameGRK6
Gene Synonyms/Alias GRK6;
Ensembl Information
Ensembl Gene IDEnsembl Protein IDEnsembl Transcript ID
ENSTGUG00000000396ENSTGUP00000000413ENSTGUT00000000419
OrganismTaeniopygia guttata
Functional Description
Protein Length549
Protein Sequence
(FASTA)
GGGGNRKGKS KKWRQMLQFP HISLCEDLRQ SLERDYHSLC EKQPIGHMLF RQFCETRPEL 60
SRCVKFLDAV AGYEVAPDEK RKECGQHLIE KYLKPNSEDH VPEVPSPLVD ACCERLEQEP 120
SKELFKECTK LIHDYLSVAP FADYLDSLYF NRFLQWKWLE RQPVTKNTFR QYRVLGKGGF 180
WEVCACQVRA TGKMYACKKL EKKRIKKRKG EAMALNEKQI LEKVNSRFVV SLAYAYETKD 240
ALCLVLTLMN GGDLKFHIYH MGEAGFEEPR AAFYAAEICC GLEDLHQERI VYRDLKPENI 300
LLDDHGHIRI SDLGLAVHVP EGQTIKGRVG TVATWVTPEV VKNERYTFSP DWWALGCLVY 360
EMIEGQSPFQ QRKKKIKREE VERLVKEVQE EYSEKFSPCA RSLCSMLLCK DPLERLGCRG 420
AGAKEVKEHP LFKHLNFRRL EAGMLDPPFK PDPWRIYCKD VLDIEQFSTV KGHSLSPTDN 480
DFYRKFATGM VIPWANEVGL CSCLLPTWPR ALSWCWQPFS PKKGLLQRLF SRQDCCGNCS 540
DSEEEPTRL 549
Nucleotide Sequence
(FASTA)
GGTGGTGGAG GAAACCGGAA AGGCAAGAGC AAGAAATGGC GCCAGATGCT GCAGTTCCCC 60
CACATCAGCC TCTGCGAGGA CCTTCGGCAA AGCCTGGAGC GGGACTACCA CAGCCTGTGC 120
GAGAAGCAGC CCATCGGGCA CATGCTCTTC CGGCAGTTCT GCGAGACGCG CCCCGAGCTC 180
TCACGCTGCG TCAAGTTCCT GGATGCTGTG GCAGGGTACG AAGTGGCTCC AGATGAGAAG 240
AGGAAGGAAT GTGGACAGCA CCTGATTGAA AAGTACTTGA AGCCAAACAG TGAGGACCAC 300
GTGCCTGAAG TTCCCTCACC ACTGGTAGAT GCCTGTTGTG AGAGGCTGGA GCAGGAACCT 360
TCCAAGGAGC TCTTCAAGGA ATGCACTAAG CTTATTCACG ACTACCTGAG CGTGGCTCCC 420
TTTGCCGACT ACCTCGACAG CTTGTACTTC AACCGCTTCC TGCAGTGGAA ATGGCTGGAA 480
CGGCAGCCAG TGACCAAAAA CACTTTCCGC CAGTACCGTG TGCTGGGTAA GGGCGGATTT 540
TGGGAGGTGT GTGCCTGCCA AGTGCGTGCC ACAGGGAAGA TGTATGCCTG CAAGAAACTG 600
GAGAAGAAAC GGATCAAAAA GAGGAAGGGA GAAGCCATGG CCCTGAATGA AAAACAGATC 660
CTGGAAAAAG TGAACAGTAG GTTTGTAGTG AGCTTAGCCT ATGCATATGA AACTAAAGAT 720
GCTCTCTGCC TAGTGCTGAC CCTCATGAAT GGAGGGGACC TCAAGTTCCA TATCTACCAC 780
ATGGGAGAGG CTGGTTTTGA GGAGCCCCGG GCAGCTTTCT ATGCTGCTGA GATCTGCTGT 840
GGCCTGGAGG ACTTGCACCA GGAGAGGATA GTGTACAGGG ACCTGAAGCC AGAGAACATA 900
TTACTGGATG ACCACGGTCA CATCCGTATC TCAGACCTGG GACTAGCTGT GCATGTGCCA 960
GAGGGCCAAA CTATCAAGGG CCGGGTGGGG ACAGTGGCTA CATGGGTAAC TCCGGAGGTG 1020
GTGAAGAACG AGCGCTACAC GTTCAGCCCG GACTGGTGGG CTCTGGGCTG CCTGGTGTAC 1080
GAGATGATCG AGGGCCAGTC CCCCTTCCAG CAGCGCAAGA AGAAGATCAA GCGGGAGGAG 1140
GTGGAGCGGT TGGTGAAGGA AGTGCAGGAG GAGTACTCGG AGAAGTTCTC GCCCTGTGCC 1200
CGCTCCCTCT GCAGCATGCT CCTGTGCAAA GACCCCTTGG AGCGCCTGGG GTGCCGAGGA 1260
GCTGGGGCCA AGGAGGTGAA GGAACACCCT CTCTTCAAGC ACCTCAACTT CAGGAGGCTG 1320
GAAGCAGGCA TGCTGGACCC TCCCTTCAAG CCCGATCCCT GGCGCATCTA CTGCAAGGAT 1380
GTTCTGGACA TCGAGCAGTT CTCCACGGTG AAAGGACATT CTCTCAGCCC CACAGACAAC 1440
GACTTTTACA GAAAGTTTGC TACAGGAATG GTCATTCCCT GGGCAAACGA GGTGGGTCTT 1500
TGCTCCTGCT TGTTGCCTAC ATGGCCGAGG GCACTGTCCT GGTGCTGGCA ACCTTTCTCC 1560
CCAAAAAAAG GGTTACTCCA GCGCTTGTTC AGCAGACAGG ACTGTTGTGG AAACTGCAGC 1620
GACAGCGAGG AAGAGCCCAC CCGGCTGTAG 1650
Domain Profile
S: 1     freyrvlGkGGfGevcacqvkatGkmyalkklekkrikkrkgealalnekkilekvdsrf  60
         fr+yrvlGkGGf evcacqv+atGkmya+kklekkrikkrkgea+alnek+ilekv+srf
Q: 169   FRQYRVLGKGGFWEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRF  228
         99**********************************************************
S: 61    vvslayafetkdklclvltlmnGGdlkyhlynleeggfeeeralfyaaeiilGlehlhke  120
         vvslaya+etkd+lclvltlmnGGdlk+h+y+++e+gfee ra fyaaei++Gle+lh+e
Q: 229   VVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGEAGFEEPRAAFYAAEICCGLEDLHQE  288
         ************************************************************
S: 121   rivyrdlkpenillddkGhvrisdlGlavelkekekikgrvGtv.Gymapevlkkekydf  179
         rivyrdlkpenilldd+Gh+risdlGlav+++e+++ikgrvGtv  +++pev+k+e+y+f
Q: 289   RIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVaTWVTPEVVKNERYTF  348
         *******************************************83599************
S: 180   sadwfalGcllyelikgkspfrqrkekvkkeevdrrvleeevkysekfseeakslleall  239
         s+dw+alGcl+ye+i+g+spf+qrk+k+k+eev+r+v+e +++ysekfs+ a+sl+++ll
Q: 349   SPDWWALGCLVYEMIEGQSPFQQRKKKIKREEVERLVKEVQEEYSEKFSPCARSLCSMLL  408
         ************************************************************
S: 240   ekdvekrlGcreegaeevkehplf  263
          kd+ +rlGcr+ ga+evkehplf
Q: 409   CKDPLERLGCRGAGAKEVKEHPLF  432
         **********************99
Domain Sequence
(FASTA)
FRQYRVLGKG GFWEVCACQV RATGKMYACK KLEKKRIKKR KGEAMALNEK QILEKVNSRF 60
VVSLAYAYET KDALCLVLTL MNGGDLKFHI YHMGEAGFEE PRAAFYAAEI CCGLEDLHQE 120
RIVYRDLKPE NILLDDHGHI RISDLGLAVH VPEGQTIKGR VGTVATWVTP EVVKNERYTF 180
SPDWWALGCL VYEMIEGQSP FQQRKKKIKR EEVERLVKEV QEEYSEKFSP CARSLCSMLL 240
CKDPLERLGC RGAGAKEVKE HPLF 264
KeywordComplete proteome; Reference proteome.
Sequence SourceEnsembl
Orthology
Ortholog group
Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>
EKS-AIM-00039
EKS-ANC-00038
EKS-BOT-00045
EKS-CAJ-00044
EKS-CAF-00044
EKS-CAP-00044
EKS-DAR-00055
EKS-EQC-00041
EKS-FEC-00041
EKS-GAG-00036
EKS-GAA-00059
EKS-GOG-00042
EKS-HOS-00044
EKS-ICT-00040
EKS-LAC-00046
EKS-LOA-00043
EKS-MAM-00042
EKS-MAE-00021
EKS-MEG-00036
EKS-MOD-00043
EKS-MUM-00045
EKS-MUP-00045
EKS-MYL-00046
EKS-NOL-00045
EKS-OCP-00032
EKS-ORN-00061
EKS-ORA-00038
EKS-ORC-00042
EKS-OTG-00046
EKS-POA-00040
EKS-PRC-00032
EKS-RAN-00045
EKS-SAH-00042
EKS-TUB-00031
EKS-VIP-00023
EKS-XET-00044
EKS-XIM-00059
Gene Ontology
GO:0005524; F:ATP binding
GO:0004703; F:G-protein coupled receptor kinase activity
GO:0007165; P:signal transduction
GO:0038032; P:termination of G-protein coupled receptor signaling pathway
KEGG
InterPros
IPR000961; AGC-kinase_C.
IPR000239; GPCR_kinase.
IPR011009; Kinase-like_dom.
IPR000719; Prot_kinase_cat_dom.
IPR000342; Regulat_G_prot_signal.
IPR016137; Regulat_G_prot_signal_superfam.
IPR002290; Ser/Thr_dual-sp_kinase_dom.
IPR008271; Ser/Thr_kinase_AS.
Pfam
PF00069; Pkinase; 1.
PF00615; RGS; 1.
SMARTs
SM00315; RGS; 1.
SM00133; S_TK_X; 1.
SM00220; S_TKc; 1.
Prosites
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; 1.
PS50132; RGS; 1.
Prints
PR00717; GPCRKINASE.
Created Date20-Feb-2013