EKS-TAG-00482

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00482

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	481.3	5.6E-145	5	267	263

Status

Unreviewed

Ensembl Protein

ENSTGUP00000001035

UniProt Accession

H0YRX5;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK3

Gene Synonyms/Alias

DAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000001010	ENSTGUP00000001035	ENSTGUT00000001047

Organism

Taeniopygia guttata

Functional Description

Protein Length

437

Protein Sequence
(FASTA)

VEDFYEMGEE LGSGQFAIVR KCRERKTGLE YAAKFIKKRR LSSSRRGVSR EEIEREVDIL 60

REIQHPNIIT LHDIFENKTD VVLILELVSG GELFDFLAEK ESLTEEEATQ FLKQILDGVH 120

YLHSKRIAHF DLKPENIMLL DKNVPNPRIK LIDFGIAHKI EAGNEFKNIF GTPEFVAPEI 180

VNYEPLGLEA DMWSIGVITY ILLSGASPFL GETKQETLTN ISAVNYDFDE EYFSNTSELA 240

KDFIRRLLVK DPKKRMTIAQ SLEHPWIKRR NVRNEDSCKK PERRRLKTTR LKEYTIKSHS 300

SMPPNNTYIN FERFSKVMEE VAAAEESLRE LERNKKSFQE DIEALLSIYE EKESWYKEEN 360

ESISQDLRQI RQELQKTEAL KKQAQEETKS VVQAANGLKR RYRKLENHYE ALAKQVASEM 420

KFVQELVWSI EREKLQS 437

Nucleotide Sequence
(FASTA)

GTGGAGGACT TCTATGAGAT GGGCGAAGAG CTGGGCAGCG GGCAGTTCGC CATCGTCCGC 60

AAGTGCCGGG AGAGGAAGAC GGGCCTGGAG TACGCGGCCA AGTTCATCAA GAAGCGGCGG 120

CTGTCGTCCA GCCGCCGGGG CGTGAGCCGC GAGGAGATCG AGCGCGAGGT GGACATCCTG 180

CGCGAGATCC AGCACCCCAA CATCATCACC CTGCACGACA TCTTCGAGAA CAAGACCGAC 240

GTGGTGCTCA TCCTGGAGCT GGTGTCCGGC GGGGAGCTCT TCGACTTCCT GGCCGAGAAG 300

GAGTCCCTGA CCGAGGAGGA GGCCACCCAG TTCCTCAAGC AGATCCTGGA CGGCGTGCAC 360

TACCTGCACT CCAAGCGCAT CGCCCACTTC GACTTGAAGC CAGAGAACAT CATGCTGCTG 420

GACAAGAACG TGCCAAACCC TCGCATCAAA CTCATCGACT TTGGGATCGC CCACAAGATC 480

GAGGCTGGGA ATGAGTTCAA GAATATCTTT GGGACCCCAG AGTTTGTAGC CCCCGAAATT 540

GTGAACTATG AGCCCCTGGG GCTGGAGGCC GACATGTGGA GCATCGGGGT CATCACCTAC 600

ATCCTGCTGA GCGGAGCCTC CCCGTTCCTG GGGGAGACCA AGCAGGAGAC ACTGACCAAC 660

ATCTCTGCTG TCAACTACGA CTTCGATGAG GAATATTTCA GCAACACCAG CGAGCTGGCC 720

AAGGACTTCA TCCGCCGCCT GCTCGTCAAG GACCCCAAGA AGCGAATGAC CATCGCCCAG 780

AGCCTGGAGC ACCCGTGGAT TAAGAGGAGG AACGTCCGCA ACGAGGACAG CTGCAAGAAG 840

CCCGAGCGGC GCCGGCTGAA GACCACGCGC CTGAAGGAGT ACACCATCAA ATCCCACTCC 900

AGCATGCCCC CCAACAACAC CTACATCAAC TTCGAGCGCT TCTCCAAGGT CATGGAGGAG 960

GTGGCTGCGG CCGAGGAGAG CCTCCGCGAG CTGGAGAGGA ACAAGAAGTC CTTCCAGGAG 1020

GACATCGAGG CGCTGCTGTC CATCTACGAG GAGAAGGAGT CGTGGTACAA GGAGGAGAAC 1080

GAGAGCATCA GCCAGGACCT GCGGCAGATC CGGCAGGAGC TGCAGAAGAC GGAGGCGCTG 1140

AAGAAGCAGG CGCAGGAGGA GACCAAGAGC GTGGTGCAGG CGGCCAACGG GCTCAAGCGG 1200

CGCTACCGCA AGCTGGAGAA CCACTACGAG GCCCTGGCCA AGCAGGTGGC CTCTGAGATG 1260

AAGTTTGTGC AGGAGCTGGT GTGGTCCATC GAGCGGGAGA AGCTGCAGAG C 1311

Domain Profile

S: 1     letgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeir  60

         +e+g+elgsG+fa+vrkcre++tG eyaakf+kkrrl+ssrrgvsreeierev +l+ei+

Q: 5     YEMGEELGSGQFAIVRKCRERKTGLEYAAKFIKKRRLSSSRRGVSREEIEREVDILREIQ  64

         5789********************************************************

S: 61    sepnvinlhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylh  120

          +pn+i+lh+++enk+dv+lilelv+GGelfd+laekesl+eeeat++lkqil+gv+ylh

Q: 65    -HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEEEATQFLKQILDGVHYLH  123

         .***********************************************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         sk+i+h+dlkPeni+lldk+vp+++iklidfG+++kie+g+e+k+i+GtPefvaPeivny

Q: 124   SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNY  183

         ************************************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         epl+le+dmwsiGvityillsgasPflG+tkqetl+nisavn+df+ee+fs++selakdf

Q: 184   EPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDF  243

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         irrllvkdp+kr+ti+++leh+w+

Q: 244   IRRLLVKDPKKRMTIAQSLEHPWI  267

         ***********************8

Domain Sequence
(FASTA)

YEMGEELGSG QFAIVRKCRE RKTGLEYAAK FIKKRRLSSS RRGVSREEIE REVDILREIQ 60

HPNIITLHDI FENKTDVVLI LELVSGGELF DFLAEKESLT EEEATQFLKQ ILDGVHYLHS 120

KRIAHFDLKP ENIMLLDKNV PNPRIKLIDF GIAHKIEAGN EFKNIFGTPE FVAPEIVNYE 180

PLGLEADMWS IGVITYILLS GASPFLGETK QETLTNISAV NYDFDEEYFS NTSELAKDFI 240

RRLLVKDPKK RMTIAQSLEH PWI 263

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:0090263	; P:positive regulation of canonical Wnt receptor signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013