EKS-TAG-00228

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00228

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	472.2	3.8E-142	4	286	283

Status

Unreviewed

Ensembl Protein

ENSTGUP00000001848

UniProt Accession

H0YU80;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000001792	ENSTGUP00000001848	ENSTGUT00000001866

Organism

Taeniopygia guttata

Functional Description

Protein Length

551

Protein Sequence
(FASTA)

MDKYQVLGLV GEGSYGVVTK CRNRENGQVV AVKKFLESDD DAAVRIALRE IKLLKQLRHE 60

NLVSLLDVCK RKKRWYLVFE FVDHTVLDDL EAFFGGLDYD RVRKYLFQIM RGIAFCHSHN 120

IIHRDIKPEN ILVSQSGVVK LCDFGFARPL ATSGEVYTDY VATRWYRAPE LLVGDSKYGR 180

PVDVWAIGSL ITEMLTGEPL FPGDSDIDQL FHITKCLGNL IPRQQELFYK NPLFAGIKLP 240

EVKELESLEK RYPKLPPAAL DLAKECLQVD PDKRPSCAEL LQGDFFNKDG FAERFTQELK 300

QKIQKDARDH QLQKNPKITK RDKDDVLEER KTISVQDFSM GPRNKDGKLI KTKPTKADAE 360

KADRSSKLDF VYDSTIHPFK FSPQTNLKDS SSSLDYTKNL GTFIPPINQN FSPTFGMGSG 420

PGNLNYRLDE KSKKYLNPLL KARKPSPVGR CSVSLTPVTN EKPILQPSKK KWEFLKTDMR 480

LPELNHLPEL RGAEGSTRQF RFLKKEKRMF AEPRVPSLAA IDLHYSSLAS QQLSGTLMPD 540

ASEANFPWVE H 551

Nucleotide Sequence
(FASTA)

ATGGACAAGT ACCAGGTGCT GGGGCTGGTG GGGGAAGGCA GCTACGGGGT GGTGACCAAG 60

TGCAGGAACA GGGAGAACGG GCAGGTGGTG GCCGTCAAGA AGTTCCTGGA GAGCGACGAC 120

GACGCGGCGG TGAGGATCGC CCTGAGGGAA ATCAAACTGC TCAAGCAACT GAGGCACGAG 180

AATCTGGTGA GCCTGTTGGA TGTGTGTAAG AGGAAGAAGC GCTGGTACCT GGTGTTTGAA 240

TTTGTGGATC ACACGGTGCT CGATGACCTC GAGGCCTTTT TTGGTGGACT GGACTACGAC 300

AGGGTTCGGA AGTACTTATT TCAGATTATG AGAGGAATTG CCTTTTGTCA CAGCCATAAT 360

ATAATCCATC GCGATATTAA GCCAGAGAAC ATACTGGTTT CCCAGTCAGG AGTTGTGAAA 420

CTCTGTGACT TTGGATTTGC CCGGCCCTTG GCGACTTCTG GGGAAGTTTA CACGGACTAC 480

GTGGCGACCC GCTGGTACAG AGCCCCGGAG CTGCTGGTGG GGGACAGCAA ATACGGCAGG 540

CCTGTGGACG TGTGGGCTAT TGGCTCCCTG ATAACAGAAA TGCTTACAGG AGAGCCCCTT 600

TTCCCTGGAG ACTCGGACAT TGACCAGCTC TTCCATATCA CCAAGTGCCT GGGTAACTTA 660

ATTCCAAGAC AACAGGAGTT ATTCTATAAA AACCCCCTCT TTGCTGGCAT AAAGTTGCCA 720

GAGGTCAAGG AACTTGAATC CCTGGAGAAA CGCTATCCCA AGCTCCCTCC TGCTGCACTG 780

GATTTAGCCA AGGAGTGTTT GCAGGTTGAC CCAGACAAGA GACCATCCTG CGCCGAACTC 840

CTGCAGGGCG ATTTCTTCAA CAAGGATGGC TTTGCTGAAA GATTTACGCA GGAGCTTAAA 900

CAAAAGATCC AGAAAGATGC CAGAGACCAT CAGTTGCAAA AAAACCCCAA AATCACTAAA 960

AGGGACAAAG ATGATGTTTT AGAAGAAAGA AAAACCATCA GCGTCCAGGA TTTCAGCATG 1020

GGCCCAAGGA ACAAAGATGG AAAGCTGATA AAGACCAAGC CCACTAAAGC TGATGCAGAG 1080

AAAGCAGATC GATCCTCCAA GCTGGACTTT GTCTACGACA GCACAATCCA CCCGTTTAAA 1140

TTCAGCCCTC AGACCAACCT GAAAGATTCG AGCAGCAGCC TGGACTACAC CAAGAACCTG 1200

GGCACATTTA TCCCTCCCAT CAACCAGAAC TTCTCTCCTA CATTTGGGAT GGGGTCTGGG 1260

CCTGGGAACC TTAATTACAG ACTTGATGAA AAGAGTAAAA AATACTTGAA CCCCTTGCTA 1320

AAGGCACGGA AGCCTTCTCC AGTGGGGCGT TGCAGTGTCA GCTTGACACC GGTTACTAAT 1380

GAAAAACCTA TCCTTCAGCC AAGTAAGAAG AAATGGGAAT TCCTCAAGAC AGACATGCGT 1440

TTGCCAGAAC TAAATCATCT CCCTGAGCTA AGGGGAGCAG AAGGAAGCAC TCGGCAATTC 1500

AGATTTCTGA AAAAGGAAAA GAGAATGTTC GCAGAGCCCC GAGTCCCCTC CCTCGCTGCT 1560

ATTGACCTTC ATTACTCAAG TCTGGCTTCA CAGCAGCTGT CAGGGACCTT GATGCCAGAT 1620

GCATCAGAAG CTAACTTCCC CTGGGTCGAG CACTAG 1656

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         y+ lg vGeGsyGvv kcrn++ gq+va+kkfles+dd +v+ ialreikllkql+henl

Q: 4     YQVLGLVGEGSYGVVTKCRNRENGQVVAVKKFLESDDDAAVR-IALREIKLLKQLRHENL  62

         889**********************************99995.*****************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+ll+v++rkk++ylvfe+vd+tvld+le +  G+++++v+k+l+qi+++i+fch++nii

Q: 63    VSLLDVCKRKKRWYLVFEFVDHTVLDDLEAFFGGLDYDRVRKYLFQIMRGIAFCHSHNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sgvvklcdfGfar la++g+vytdyvatrwyrapellvgd+kyG++v

Q: 123   HRDIKPENILVSQSGVVKLCDFGFARPLATSGEVYTDYVATRWYRAPELLVGDSKYGRPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiG l++e+ltGeplfpg+sd+dql++i+k+lG+lipr+q++f+kn++faG+klpev

Q: 183   DVWAIGSLITEMLTGEPLFPGDSDIDQLFHITKCLGNLIPRQQELFYKNPLFAGIKLPEV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ++leslek+ypkl +++ldl+k+cl++dp++r sc+ell+ ++f

Q: 243   KELESLEKRYPKLPPAALDLAKECLQVDPDKRPSCAELLQGDFF  286

         ****************************************9998

Domain Sequence
(FASTA)

YQVLGLVGEG SYGVVTKCRN RENGQVVAVK KFLESDDDAA VRIALREIKL LKQLRHENLV 60

SLLDVCKRKK RWYLVFEFVD HTVLDDLEAF FGGLDYDRVR KYLFQIMRGI AFCHSHNIIH 120

RDIKPENILV SQSGVVKLCD FGFARPLATS GEVYTDYVAT RWYRAPELLV GDSKYGRPVD 180

VWAIGSLITE MLTGEPLFPG DSDIDQLFHI TKCLGNLIPR QQELFYKNPL FAGIKLPEVK 240

ELESLEKRYP KLPPAALDLA KECLQVDPDK RPSCAELLQG DFF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013