EPS-TAG-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	206.3	5.9E-61	651	896	246

Status

Unreviewed

Ensembl Protein

ENSTGUP00000002089

UniProt Accession

H0YUW9;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000002028	ENSTGUP00000002089	ENSTGUT00000002109

Organism

Taeniopygia guttata

Functional Description

Protein Length

1180

Protein Sequence
(FASTA)

SGKPHSTGSS ERIQLSGMYN VRKGKIHLPV NRWTRRQAIL CGTCLIVSSV KESQTGKMHV 60

LPLIGGKVEE VKKHQHCLAF SSSGPQSQTY YICFDNFTEY LRWLRQASKV ASQRISSVDL 120

SCCSLEHLPA NLFYSQDLTH LNLKQNFLRL NPSPSTSRAL SELQRFTKLK SLNLSNNNLG 180

DFPLAVCSIP TLTELNLSCN ALRSIPAVVG EMHNLQTFLL DGNFLQSLPD ELEHIHQLSY 240

VSLSFNEFTD IPGVLEKLTA MDKLCMSGNC IDTLNLQVLK RMPHIKHVDL RLNSIRRLES 300

DEIDFLHHVT QLDLRDNKLG ELDATVFNNV EVLHCERNQL VTLKISGYFL KALYASCNEL 360

VHLDVYPVPN CLAYMDISRN HLENLPEWVC DSRKLEVLDV GHNQIRELPA RLFYNSSLRK 420

LLAGHNMLGR LPDRLERTQV EVLDVQHNQL LELPSNLLLK ADSLRFLNAS ANKLEMLPPA 480

TLSEETHSIL QELYLTNNNL TDKCVPLLTG HPHLKILHMA YNRLQSFPAS KMAKLEELEE 540

IDISGNKLKA IPTTIMNCRR MHTVIAHSNC IEVFPEVMQL SEIKCVDLSC NELSEVTLPE 600

NLPPKLQELD LTGNPRLALD HKTLELLNNI RCFKIDQPSA GDASGAPAVW SHGYTEASGV 660

KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ KTKNEEEYMI 720

NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGCFTLT SANVGKCQTV LCRNGKPLPL 780

SRCYVMSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVVPR PHVQSITLTP 840

QDEFFILGSK GLWDSLSMDE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS ISAVVVQLNV 900

TEDSFCCCEL NGVPPPSPGI FPQSVNVVIK DRPADALGMP SSSSGMASEI SSEISTSEMS 960

SEVGSTASDE PPQVTMNENS PAYPGEQRCM LHPVCLSNSF QRQLSSATFS SAFSDNGLDS 1020

DDEEPIEGVF TNGSRVEVEV DIHCSRAKEK QLLQVPVEAS DEGIVISANE DEPGLPRKAE 1080

YSATGTIGRR RGNGSVAPHE RSHNLIEVAT DAPLRKTGGY FAAPAQPDPD DQFIIPPELE 1140

EEVKEIMKQH QEQQQQQQQQ QQQQKQYPMD HLADYYDTPL 1180

Nucleotide Sequence
(FASTA)

TCAGGAAAGC CCCACAGCAC TGGCAGCTCC GAACGGATTC AGCTCTCAGG AATGTACAAT 60

GTTCGAAAAG GGAAAATACA TTTGCCAGTC AACAGATGGA CAAGACGCCA AGCTATCCTT 120

TGTGGAACAT GCCTAATTGT CTCATCAGTA AAAGAAAGCC AGACTGGAAA GATGCATGTC 180

CTTCCTTTAA TTGGTGGAAA AGTGGAAGAA GTGAAAAAGC ACCAGCACTG TTTAGCATTT 240

AGCTCCTCTG GACCTCAAAG CCAGACCTAC TACATTTGTT TTGATAACTT CACTGAATAT 300

CTGCGATGGC TGCGACAAGC ATCAAAGGTT GCATCACAAC GCATCAGCTC AGTGGATCTT 360

TCATGCTGCA GCCTGGAGCA CCTGCCTGCC AACCTGTTTT ATAGCCAAGA CCTCACTCAT 420

CTCAATTTAA AGCAGAACTT CCTGAGGCTA AACCCCAGCC CATCCACAAG TAGAGCGCTT 480

AGTGAATTAC AAAGATTCAC CAAATTGAAG AGCCTTAACC TTTCGAATAA CAATTTAGGA 540

GACTTCCCAC TGGCAGTCTG CAGTATCCCA ACCCTGACTG AACTCAACCT GTCCTGCAAT 600

GCCCTCAGAA GCATTCCAGC AGTTGTAGGC GAAATGCACA ACTTGCAGAC ATTTTTGCTG 660

GATGGCAACT TTCTCCAGTC CCTTCCTGAT GAATTGGAGC ATATTCATCA ACTCAGCTAT 720

GTGAGTCTGT CCTTCAATGA GTTCACTGAC ATTCCTGGAG TGCTGGAGAA GCTGACTGCC 780

ATGGATAAGC TGTGTATGTC AGGAAACTGC ATAGATACCC TGAACCTACA GGTGTTAAAA 840

AGGATGCCTC ATATTAAGCA TGTGGATCTA AGATTGAATT CAATTAGAAG ATTGGAGTCT 900

GATGAAATAG ATTTTCTGCA TCATGTGACC CAGCTGGATC TGCGAGACAA CAAACTTGGG 960

GAGCTGGACG CAACAGTTTT TAACAATGTG GAAGTGTTAC ACTGTGAACG GAATCAGCTG 1020

GTGACCCTCA AAATCAGTGG CTATTTTCTC AAAGCTCTGT ACGCTTCCTG CAATGAACTT 1080

GTTCACCTTG ATGTGTATCC AGTTCCTAAT TGCCTGGCTT ATATGGATAT TTCTAGAAAT 1140

CACCTGGAGA ACCTGCCTGA GTGGGTGTGT GACAGCAGGA AACTGGAAGT GTTGGATGTT 1200

GGCCACAATC AGATACGTGA GCTGCCTGCC CGGTTGTTTT ACAATAGTAG CTTGCGGAAG 1260

CTGCTGGCGG GACATAATAT GTTAGGAAGG CTCCCAGATC GGCTCGAGCG AACGCAGGTG 1320

GAGGTCCTGG ACGTGCAGCA CAACCAGCTC CTGGAACTGC CTTCTAACCT GCTTTTGAAA 1380

GCAGACAGCC TGAGATTTCT TAATGCCTCT GCCAACAAAC TGGAAATGCT TCCTCCGGCC 1440

ACTCTTTCTG AAGAAACCCA TAGCATCTTG CAGGAGTTGT ATTTGACCAA TAACAACCTC 1500

ACAGATAAAT GTGTACCCTT GTTAACAGGC CACCCACACC TAAAAATCTT GCACATGGCT 1560

TACAATCGCC TACAGAGCTT CCCTGCAAGC AAAATGGCCA AGCTGGAGGA GTTGGAGGAA 1620

ATTGATATTA GTGGGAACAA ACTGAAAGCC ATTCCAACAA CCATCATGAA CTGCAGACGT 1680

ATGCATACTG TAATTGCTCA CTCCAACTGC ATTGAAGTCT TCCCAGAAGT CATGCAGCTT 1740

TCTGAAATAA AGTGTGTGGA CCTAAGCTGC AATGAACTGA GTGAAGTCAC ATTGCCTGAA 1800

AATCTGCCTC CAAAACTGCA GGAGCTGGAC CTGACTGGAA ATCCCAGATT AGCCCTGGAT 1860

CACAAAACCC TAGAGCTTCT GAACAATATC CGGTGCTTCA AGATCGACCA GCCGTCGGCC 1920

GGCGACGCGT CGGGAGCGCC GGCGGTGTGG AGTCACGGCT ACACGGAGGC GTCCGGCGTC 1980

AAGAACAAGC TGTGTGTGGC AGCGCTTTCG GCCAACAACT TCTGCGACAA CCGGGAGGCC 2040

CTTTATGGTG TGTTTGATGG GGACCGCAAT GTGGAAGTGC CCTATCTGCT GCAGTGCACA 2100

ATGAGTGACA TCCTGGCAGA AGAGCTGCAG AAAACAAAGA ATGAGGAGGA ATACATGATC 2160

AACACTTTCA TTGTTATGCA GAGGAAACTT GGAACGGCTG GGCAGAAACT TGGAGGCTCT 2220

GCTGTCCTTT GCCACATAAA ACATGATCCC ATGGACCCTG GTGGATGCTT CACGCTAACC 2280

TCAGCAAACG TGGGGAAGTG CCAAACCGTT CTCTGCCGGA ATGGGAAACC TCTGCCTTTG 2340

TCCAGGTGTT ATGTGATGAG CTGTGAAGAA GAGCTGAAGA GGATTAAGCA ACATAAGGCC 2400

ATTATCACAG AGGATGGCAA AGTGAATGGT GTGACAGATT CAACAAGAAT CTTGGGGTAC 2460

ACCTTCCTTC ACCCAAGTGT TGTGCCGCGT CCTCACGTCC AGTCCATTAC CTTAACTCCA 2520

CAAGATGAGT TCTTCATTTT GGGGAGCAAG GGGCTGTGGG ACAGTCTCTC CATGGATGAA 2580

GCAGTTGAGG CCGTCAGAAA CGTGCCTGAT GCGCTGGCAG CCGCCAAGAA GCTTTGCACT 2640

TTGGCCCAGA GTTACGGCTG CAACGACAGC ATCAGCGCTG TCGTGGTTCA GCTCAATGTG 2700

ACGGAGGACA GCTTCTGCTG CTGTGAGCTC AATGGGGTCC CGCCCCCCAG CCCCGGCATC 2760

TTCCCCCAGT CTGTCAACGT GGTCATCAAG GACAGGCCTG CAGACGCGCT CGGGATGCCG 2820

TCTTCGAGCA GCGGCATGGC TTCCGAAATC AGCAGCGAGA TCTCCACCTC GGAAATGAGC 2880

AGCGAGGTGG GGTCCACAGC CTCCGACGAG CCTCCCCAGG TGACCATGAA CGAGAACAGC 2940

CCGGCGTACC CAGGAGAGCA GCGCTGCATG CTGCACCCCG TCTGCCTGTC CAACTCTTTC 3000

CAGCGGCAGC TCTCCAGCGC CACCTTCTCC AGCGCCTTCT CCGACAACGG CCTTGACAGC 3060

GACGACGAGG AGCCCATCGA GGGGGTGTTC ACCAATGGCA GCCGCGTGGA GGTGGAGGTG 3120

GACATCCACT GCAGCCGAGC GAAGGAGAAG CAGCTTCTCC AAGTGCCAGT GGAAGCCAGT 3180

GACGAAGGGA TCGTCATCAG TGCCAATGAA GATGAGCCCG GCCTTCCCAG GAAAGCTGAA 3240

TATTCTGCCA CAGGCACAAT AGGGCGCCGG CGGGGCAACG GCTCTGTGGC ACCACACGAG 3300

AGGAGCCATA ACTTAATTGA AGTTGCAACA GATGCGCCAC TCAGAAAAAC CGGGGGCTAC 3360

TTTGCTGCTC CAGCACAACC TGATCCTGAT GACCAGTTCA TCATCCCACC AGAGCTTGAA 3420

GAAGAAGTCA AGGAGATTAT GAAGCAGCAC CAGGAACAAC AACAACAACA GCAGCAGCAG 3480

CAGCAACAGC AGAAGCAGTA TCCGATGGAC CACCTGGCAG ACTATTATGA CACACCACTA 3540

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 651   SHGYTEASGVKNKLCVAALSANNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  705

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 706   AEELQ----KTKNEEEYMINTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpgg  755

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv+

Q: 756   cfTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDG--KVNGVTD  813

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s  eav++vr+v +

Q: 814   STRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPD---  870

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 871   -ALAAAKKLCTLAQSYGCNDSISAVVV  896

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMI NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGCFTLT SANVGKCQTV 120

LCRNGKPLPL SRCYVMSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVVPR 180

PHVQSITLTP QDEFFILGSK GLWDSLSMDE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>