EPS-TAG-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	223.9	2.6E-66	95	344	250

Status

Unreviewed

Ensembl Protein

ENSTGUP00000002579

UniProt Accession

H0YWA6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1K

Gene Synonyms/Alias

PPM1K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000002504	ENSTGUP00000002579	ENSTGUT00000002607

Organism

Taeniopygia guttata

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSTATLINLV RNGGFQVRRR AALRSRFLQD EKRPAAACSI STCERRASRF DPDGSGRPTT 60

WDTFGIWDNR IDEPILLPPS IKYGKPIPKV SLSNVGCASH IGKRKENEDR FDYAQLTEDI 120

LYFAVYDGHG GAAAADFCDK YMEKYIKEFL AEEENLENAL SKAFLEIDKA YERHANLSAD 180

ATLLSSGTTA TVALLRDGIE LVVASVGDSR ALLCRKGKPM KLTIDHTPER KEEKERIKKC 240

GGFVSWNSLG QPHVNGRLAM TRSIGDLDLK NSGVIAQPET KRVQLHHADD SFLVLTTDGI 300

NFIVNSQEIC NFISQCHDPA EAAHVLTEQA VHFGSEDNST VVIVPFGAWG KYKNGEVTFS 360

FSRSFASSGR WA 372

Nucleotide Sequence
(FASTA)

ATGTCCACAG CTACTCTGAT TAATTTGGTA CGGAATGGAG GGTTCCAAGT AAGAAGGAGA 60

GCCGCGCTCA GGTCCCGCTT CCTGCAGGAC GAGAAGCGCC CCGCAGCCGC CTGCTCCATC 120

TCCACCTGCG AGCGCCGCGC CTCCCGCTTC GACCCCGACG GGAGCGGGCG GCCGACCACA 180

TGGGACACCT TCGGCATCTG GGACAATCGC ATCGATGAAC CCATCCTCCT CCCACCCAGC 240

ATAAAGTACG GGAAGCCGAT CCCAAAGGTG AGCCTGAGCA ACGTAGGCTG CGCCAGCCAC 300

ATCGGGAAGC GAAAGGAAAA CGAGGACCGG TTCGATTACG CTCAGCTGAC AGAGGATATC 360

CTGTACTTCG CAGTGTACGA TGGGCATGGT GGGGCAGCAG CCGCTGACTT CTGTGATAAG 420

TACATGGAAA AATATATTAA GGAATTTCTT GCCGAGGAGG AGAACCTGGA AAATGCTTTG 480

AGCAAAGCTT TTCTAGAAAT AGACAAAGCA TATGAAAGGC ATGCTAATCT CTCTGCTGAT 540

GCAACTCTGC TGAGCTCTGG GACCACTGCA ACAGTGGCTC TGCTCCGGGA TGGAATTGAG 600

CTGGTTGTGG CAAGTGTGGG AGACAGTCGC GCTCTGCTTT GCCGGAAAGG AAAGCCTATG 660

AAACTCACCA TTGACCATAC TCCAGAGAGA AAGGAGGAGA AGGAAAGGAT TAAGAAGTGT 720

GGTGGCTTCG TTTCCTGGAA CAGTTTGGGA CAACCTCATG TGAATGGTAG ACTTGCAATG 780

ACACGGAGCA TAGGAGATTT GGATCTTAAA AACAGTGGTG TGATAGCCCA GCCAGAAACA 840

AAAAGGGTTC AGCTGCACCA TGCAGACGAC AGCTTCCTGG TGCTGACAAC TGATGGCATC 900

AACTTCATCG TGAACAGCCA GGAGATCTGC AACTTCATCA GCCAGTGCCA TGACCCTGCT 960

GAGGCTGCCC ACGTGCTCAC TGAGCAGGCA GTGCATTTTG GTTCTGAAGA CAACAGCACA 1020

GTTGTCATAG TGCCATTTGG AGCTTGGGGC AAGTACAAGA ATGGGGAGGT GACCTTTTCC 1080

TTCAGCCGCA GTTTCGCTTC CAGCGGGAGG TGGGCGTGA 1119

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         vg++s  g+r+e ed++++    ++ +e  d + +f+vyDGhgg  +a+fc + ++++++

Q: 95    VGCASHIGKRKENEDRFDY----AQLTE--D-ILYFAVYDGHGGAAAADFCDKYMEKYIK  147

         7999999999999999976....33322..2.78**************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidk....sGstavvalikds.kl  117

         e l     ee+++++al kaFl++d++++   +  ++  +    sG+ta+val++d  +l

Q: 148   EFLA----EEENLENALSKAFLEIDKAYERHANL-SAD-AtllsSGTTATVALLRDGiEL  201

         **99....9*******************333333.333.34799*************9**

S: 118   yvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd.ga.RvlGvLavs  175

         +va vGdSra+Lcr+gk+++l+ dH+p+r++E+eRi++ gg v  ++ g+ +v+G La++

Q: 202   VVASVGDSRALLCRKGKPMKLTIDHTPERKEEKERIKKCGGFVSWNSlGQpHVNGRLAMT  261

         *******************************************98889999*********

S: 176   RalGdlylk.pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekke  233

         R++Gdl+lk + v+++Pe+  ++l++ d+ fl+L +DG+  +v+++e+++++ ++++

Q: 262   RSIGDLDLKnSGVIAQPETKRVQLHHADDsFLVLTTDGINFIVNSQEICNFISQCHD---  318

         *********555************999999***************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + eaa+ L+++a++ gs+dn ++++v

Q: 319   -PAEAAHVLTEQAVHFGSEDNSTVVIV  344

         .*********************88775

Domain Sequence
(FASTA)

VGCASHIGKR KENEDRFDYA QLTEDILYFA VYDGHGGAAA ADFCDKYMEK YIKEFLAEEE 60

NLENALSKAF LEIDKAYERH ANLSADATLL SSGTTATVAL LRDGIELVVA SVGDSRALLC 120

RKGKPMKLTI DHTPERKEEK ERIKKCGGFV SWNSLGQPHV NGRLAMTRSI GDLDLKNSGV 180

IAQPETKRVQ LHHADDSFLV LTTDGINFIV NSQEICNFIS QCHDPAEAAH VLTEQAVHFG 240

SEDNSTVVIV 250

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

tgu:100227426

;

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013