EKS-TAG-00291

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00291

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	448.6	7.9E-135	209	496	288

Status

Unreviewed

Ensembl Protein

ENSTGUP00000003297

UniProt Accession

H0YYB9;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1B

Gene Synonyms/Alias

BMPR1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000003164	ENSTGUP00000003297	ENSTGUT00000003330

Organism

Taeniopygia guttata

Functional Description

Protein Length

507

Protein Sequence
(FASTA)

ATFLNSMALR SSGKLSMETR KDGESMAPAP PQKKLSCQCH HHCPEDAVNN TCSTDGYCFT 60

IIEEDESGGH LVTKGCLGLE GSDFQCRDTP IPHQRRSIGC CTGQDYCNRY LHPTLPPLKN 120

RDFAEGNIHH KALLISVTVC SILLVLIIIF FYFRYKRQET RPHYSIGLEQ DETYIPPGES 180

LKDLIEQSQS SGSGSGLPLL VQRTIAKQIQ MVKQIGKGRY GEVWMGKWRG EKVAVKVFFT 240

TEEASWFRET EIYQTVLMRH ENILGFIAAD IKGTGSWTQL YLITDYHENG SLYDYLKSTT 300

LDTKAMLKLA YSSVSGLCHL HTEIFSTQGK PAIAHRDLKS KNILVKKNGT CCIADLGLAV 360

KFISDTNEVD IPPNTRVGTK RYMPPEVLDE SLNRNHFQSY IMADMYSFGL ILWEIARRCV 420

SGGIVEEYQL PYHDLVPSDP SYEDMREIVC IKRLRPSFPN RWSSDECLRQ MGKLMMECWA 480

HSPASRLTAL RVKKTLAKMS ESQDIKL 507

Nucleotide Sequence
(FASTA)

GCCACTTTTC TAAACAGCAT GGCCTTGCGA AGTTCTGGCA AGCTGAGCAT GGAGACCAGG 60

AAAGATGGTG AGAGTATGGC CCCTGCTCCT CCTCAGAAGA AGCTGTCCTG CCAGTGCCAC 120

CACCACTGCC CTGAGGATGC TGTCAACAAC ACCTGCAGCA CCGATGGCTA CTGCTTCACC 180

ATAATAGAAG AGGATGAGTC TGGTGGACAT TTAGTCACCA AGGGATGTCT TGGATTAGAG 240

GGCTCAGACT TCCAGTGTCG GGACACTCCT ATTCCACACC AAAGAAGATC TATTGGATGT 300

TGCACAGGCC AAGATTACTG TAACAGATAC CTTCACCCTA CACTGCCACC ACTGAAGAAT 360

CGAGACTTTG CGGAAGGAAA CATTCACCAC AAGGCCTTGC TGATCTCAGT GACTGTTTGC 420

AGCATCCTTC TGGTGCTTAT CATCATATTT TTCTACTTCA GATACAAACG CCAAGAGACG 480

AGGCCCCACT ACAGCATCGG GCTGGAGCAG GATGAGACCT ACATTCCCCC CGGAGAGTCC 540

CTGAAGGATT TGATCGAGCA GTCCCAGAGC TCAGGCAGCG GTTCCGGGCT CCCTCTCCTG 600

GTTCAAAGGA CCATTGCAAA ACAGATTCAA ATGGTGAAGC AGATTGGAAA AGGTCGCTAT 660

GGAGAAGTCT GGATGGGAAA GTGGCGTGGC GAAAAGGTAG CAGTGAAAGT GTTTTTTACT 720

ACAGAGGAGG CCAGCTGGTT CAGAGAAACA GAAATCTACC AGACTGTCCT GATGAGGCAT 780

GAAAATATTC TTGGATTCAT TGCTGCAGAT ATTAAAGGTA CAGGATCTTG GACCCAGCTG 840

TATCTTATCA CTGACTACCA TGAGAACGGC TCACTTTATG ATTATCTAAA ATCTACTACC 900

TTGGACACAA AAGCCATGCT GAAACTGGCT TACTCCTCTG TCAGTGGCTT GTGCCACCTG 960

CACACTGAGA TCTTCAGTAC TCAGGGCAAA CCTGCTATTG CCCACCGTGA CCTAAAGAGT 1020

AAGAATATCC TGGTGAAAAA GAATGGCACC TGCTGTATAG CAGATTTGGG CTTGGCTGTT 1080

AAATTTATCA GTGATACAAA TGAGGTAGAC ATCCCTCCAA ATACCCGTGT AGGAACAAAA 1140

CGTTATATGC CTCCTGAGGT GCTGGATGAA AGCTTGAATA GAAATCACTT TCAGTCCTAC 1200

ATCATGGCTG ATATGTACAG TTTTGGACTC ATCCTTTGGG AGATAGCAAG GAGATGTGTT 1260

TCAGGAGGAA TAGTTGAAGA ATACCAGCTT CCGTACCACG ACCTTGTGCC CAGCGACCCC 1320

TCATACGAGG ACATGCGGGA GATCGTGTGC ATCAAGAGAC TACGCCCCTC CTTTCCCAAC 1380

AGATGGAGCA GTGATGAGTG CCTACGGCAG ATGGGGAAGC TGATGATGGA GTGCTGGGCT 1440

CACAGCCCTG CCTCCCGCCT CACAGCCCTG CGCGTCAAGA AAACACTTGC CAAAATGTCA 1500

GAGTCCCAGG ACATTAAACT C 1521

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 209   IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  268

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+dyLk++tld++ +l+la+s +sGl+hLH+ei+ t+

Q: 269   ADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKAMLKLAYSSVSGLCHLHTEIFSTQ  328

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNilvkk++tcciaDlGLa+k+ ++++e+d+  n++vGtkRYm PE

Q: 329   G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPE  386

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+++ +aD+Ys+gL+lWE+a+Rc + +++veey+lp+++ v+sdPs+e+m

Q: 387   VLDESLNRNHFQSYIMADMYSFGLILWEIARRCVS-GGIVEEYQLPYHDLVPSDPSYEDM  445

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +e+v+ k+lrP++p++w+++e+l+++ kl+ ecW++ p++Rltalrvkk+l

Q: 446   REIVCIKRLRPSFPNRWSSDECLRQMGKLMMECWAHSPASRLTALRVKKTL  496

         *************************************************97

Domain Sequence
(FASTA)

IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDTKAMLK LAYSSVSGLC HLHTEIFSTQ 120

GKPAIAHRDL KSKNILVKKN GTCCIADLGL AVKFISDTNE VDIPPNTRVG TKRYMPPEVL 180

DESLNRNHFQ SYIMADMYSF GLILWEIARR CVSGGIVEEY QLPYHDLVPS DPSYEDMREI 240

VCIKRLRPSF PNRWSSDECL RQMGKLMMEC WAHSPASRLT ALRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005025	; F:transforming growth factor beta receptor activity, type I
GO:0030509	; P:BMP signaling pathway
GO:0030154	; P:cell differentiation
GO:0006954	; P:inflammatory response
GO:0030501	; P:positive regulation of bone mineralization
GO:0045669	; P:positive regulation of osteoblast differentiation

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013