EKS-TAG-00233

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00233

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF3	498.4	9.5E-150	1327	1658	332

Status

Unreviewed

Ensembl Protein

ENSTGUP00000003789

UniProt Accession

H0YZQ5;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK269

Gene Synonyms/Alias

SGK269;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000003685	ENSTGUP00000003789	ENSTGUT00000003831

Organism

Taeniopygia guttata

Functional Description

Protein Length

1741

Protein Sequence
(FASTA)

MSACNTFTEH VWKPGECKNC FKPKSLHQLP PVSEKKPLSH GNLKPNANQS SSQRGRFRPP 60

VAKKPTIAVK PTMMVADGLC GELATLEQCE NKALPAGWNR NKAVLNKKPL NNNNEEEIEG 120

YSHVPRPYGN SEGVGKVPSN NNNGLTEVLK EIAGLDTTPQ LTGNETNSRE TFLGRINNCY 180

KRSLERKIPP SCMVAGMKDS QSKHVILSGS TEVISNEGGR FCYPELSSGD ESEDDTFFGS 240

MQEEHESWDE SDEELLAMEI RMRGQPRFAN FRANTLSPVP FCVDKKWNTV PLRNKSLQRI 300

CAVDYDDSYD EILNGYGEET VILYGQESMQ SMVSSDSTSP DSSLTEESRS GTTSSSSQKL 360

CNGGLSPSTP QDLKVIEPEY ESLCDNQQVK DVPKAPRNAL KSQETHKAVL ALRLEEKDGK 420

IAVQTDTQEN KSSSDAAGQA VTINLVPVEE QAKPYRVVNM EQPVCKPYTV VDVSAAMTSE 480

CKENQTETSE TKKASSSPSS PVTPGTPIAS SAASPVRVHA NLKKSSAIRY QEVWTSSTSP 540

RQKIPKVELI GNSSGPSVPP RKTSHKSAPT SPTATNVSSK TIPVKSPNLS EIKFNSYNNA 600

GMPPFPIIIH DEPTYARSSK NAIKVPIVIN PNAYDNLAIY KSFLGTTGEL SVKDKTTSVI 660

SHTYEEIETE SKGTEAIGSK STELPQARGV ASSSECRLGS VAQKVQEFNS CLTKSQISPQ 720

RSHSADHSSP SRVQKAMQEP AAKADITPDG SIGSSGGREN ASTVLSQIVA SIQPPQSPPE 780

TPQSAPKSCS VEELYSLPPE GDATKNTLVR PKSLFTSQPE MESTAIKMQK DPLSQPAATP 840

SPKPARATPS AVSPQAEQAP PFPPPRSTSS PYHASNLLQR HFSSWAKPNS PTRSTEAESI 900

LHSEGRRPDA KPKRWISFKS FFRRRKADDE EEREKEREKG KLVGLDGTVI HMLPPPPVQR 960

HHWFSEAKSD SSEKPSIVFM YRCDPAQGEP RAELPHQAGL DSAIAEALAK DKGETQEKPP 1020

ESSEQNIAGH SSPPQAPKKI PSQVPDDPAL EELSPRVPRA VFVKQDNGGS ASVIPVSAAR 1080

APPAEEEKEE APNSPDISTC SATYSNLGQS RAAMIPPKQP RQPKGALDDA IAFGGLADQE 1140

TVNSLQPTPP PLPKKTILRA NTEPTPRDLQ KQALENNLCI MANPTYDIDT NWEASSACSS 1200

VSLELKVLDN ESGDSLDRPT EKLRAATSAT NSVSSLTTLS VKERCSNSME SLTGRRLAQA 1260

RQGRGVQKPQ RQALYRGIEN REEVVGKIRS LHADSLKKLA LRCEDLFMAG QKDQLRFGVD 1320

SWSDFRLTSD KPCCEAGDAV YYPASYAKDP LNNYAVKICK SKAKESQQYY HSLSIRQSLA 1380

INFNIQQDCG HFLAEVPVRL LPWEDDDAPD VEEEREEEEK EAEQKSRDAA SSPEASRRDS 1440

PSRQGTTSKP RSRVVVITRE VPQLTVADFV RESAPRHSKS PDLYERQVCL LLLQLCLGLE 1500

HLKPYHITHC DLRLENLLLV HSRPGGSALS PEATEPNPNT ACPARLIVSN FSQAKQKSHM 1560

VDPEVLRDQS RLAPEIITAT QYKKCDEFQT GILIYEMLHL PNPFDENPEL KEKEYTCADL 1620

PKIPCRSLYS QGLQQLASCL LNPNPSERIL ISEAKGILQC LLWGPREDLF HALSTSSNPS 1680

RRDAILQNWL DIKRTLLMIK FAEKSLERDC GIILEDWLCC QYLAFATTDS LHRIVRLMKQ 1740

H 1741

Nucleotide Sequence
(FASTA)

ATGTCTGCTT GCAACACTTT CACTGAGCAC GTGTGGAAAC CCGGTGAATG TAAGAACTGC 60

TTCAAGCCCA AGAGCTTGCA CCAGCTACCC CCAGTGTCAG AAAAGAAGCC CCTCTCGCAT 120

GGAAACCTGA AACCCAATGC AAACCAGAGC AGCAGCCAGC GTGGCAGGTT CCGGCCGCCC 180

GTGGCCAAGA AGCCGACGAT AGCTGTGAAA CCCACCATGA TGGTGGCCGA CGGGCTCTGC 240

GGGGAGCTGG CCACGCTGGA GCAGTGCGAG AACAAAGCCC TGCCCGCGGG GTGGAACCGC 300

AACAAGGCGG TGCTGAACAA AAAACCACTG AACAACAACA ATGAGGAGGA GATCGAGGGC 360

TACAGCCATG TGCCTAGGCC TTATGGCAAC AGCGAGGGCG TGGGTAAGGT ACCCAGTAAC 420

AATAATAATG GACTGACAGA AGTTCTGAAG GAGATTGCAG GTTTGGATAC CACACCTCAG 480

CTCACTGGAA ATGAAACAAA CTCCAGGGAA ACCTTCTTGG GAAGGATAAA TAATTGTTAC 540

AAAAGATCAT TAGAAAGGAA GATCCCTCCG AGCTGCATGG TGGCTGGAAT GAAGGATTCA 600

CAGAGTAAGC ATGTTATTCT GAGTGGAAGC ACTGAAGTCA TAAGTAATGA AGGTGGACGT 660

TTCTGTTATC CAGAGTTGTC TAGTGGAGAT GAGAGTGAGG ATGACACGTT TTTTGGCAGC 720

ATGCAGGAAG AGCACGAGAG CTGGGATGAA AGTGATGAAG AGCTGTTAGC AATGGAAATC 780

CGGATGAGGG GCCAACCTCG CTTTGCTAAT TTCAGAGCTA ACACCCTGTC TCCTGTTCCG 840

TTTTGTGTTG ACAAAAAATG GAATACCGTG CCCCTTCGGA ACAAGTCTCT CCAGCGGATC 900

TGTGCCGTGG ATTACGATGA CAGTTATGAT GAAATTTTGA ATGGTTACGG GGAAGAGACT 960

GTGATTCTTT ATGGGCAAGA GAGCATGCAG AGCATGGTAT CTTCTGATTC TACATCTCCT 1020

GATTCTTCTT TGACGGAAGA GTCTCGTTCT GGGACAACCA GCAGTTCTTC CCAGAAGCTC 1080

TGTAATGGAG GCTTATCTCC TAGCACTCCT CAGGACCTCA AAGTAATTGA ACCAGAATAT 1140

GAAAGTCTAT GTGACAATCA ACAAGTGAAA GATGTGCCAA AAGCACCCAG AAATGCTCTG 1200

AAAAGTCAGG AAACTCACAA AGCTGTCCTT GCGCTTCGCC TGGAGGAGAA GGATGGCAAA 1260

ATTGCTGTGC AGACTGATAC GCAGGAGAAT AAAAGTTCTT CAGATGCTGC TGGTCAGGCC 1320

GTAACTATTA ATTTGGTGCC TGTGGAGGAG CAAGCTAAGC CTTACAGGGT GGTGAACATG 1380

GAACAACCAG TGTGCAAGCC ATACACCGTA GTGGATGTAT CAGCTGCCAT GACCAGTGAA 1440

TGTAAAGAGA ATCAGACTGA AACCTCAGAA ACCAAAAAGG CATCATCTAG CCCAAGCTCA 1500

CCAGTAACCC CAGGCACACC TATTGCATCC TCTGCAGCAT CACCTGTACG TGTACACGCT 1560

AATCTGAAAA AATCCAGCGC AATCAGATAC CAAGAAGTGT GGACTTCTAG CACTAGTCCA 1620

AGACAGAAGA TACCTAAGGT GGAACTGATT GGAAACAGCT CAGGACCTTC TGTTCCTCCC 1680

AGGAAGACAA GCCACAAGTC AGCTCCTACT TCACCTACAG CTACAAACGT TTCTTCGAAA 1740

ACTATCCCAG TTAAGTCTCC CAATTTGTCT GAGATAAAAT TCAACAGTTA CAACAATGCT 1800

GGCATGCCAC CTTTCCCTAT TATCATTCAT GATGAGCCCA CTTACGCTAG GAGTTCCAAA 1860

AATGCTATTA AAGTTCCTAT TGTAATCAAT CCAAATGCAT ATGATAACTT GGCAATCTAT 1920

AAAAGTTTTC TAGGGACCAC TGGGGAGCTC TCTGTCAAAG ATAAAACTAC AAGTGTGATA 1980

AGCCATACCT ATGAAGAAAT AGAAACTGAA AGTAAAGGCA CCGAAGCCAT AGGCAGCAAA 2040

TCCACTGAGT TGCCCCAAGC AAGAGGGGTG GCCAGTAGCT CTGAGTGCAG GCTGGGCTCT 2100

GTGGCTCAAA AGGTCCAAGA GTTCAACAGC TGCCTCACTA AAAGCCAGAT ATCCCCACAG 2160

AGAAGCCACA GTGCTGACCA CAGCTCCCCA TCCAGAGTTC AAAAGGCAAT GCAAGAGCCT 2220

GCAGCAAAAG CAGACATAAC CCCAGATGGT TCCATTGGCA GCAGTGGTGG CAGAGAGAAT 2280

GCGAGCACAG TGCTCTCACA GATTGTGGCT TCTATCCAGC CTCCACAGTC TCCTCCAGAA 2340

ACGCCTCAGT CTGCTCCCAA GTCCTGTAGT GTAGAAGAAC TGTATTCCTT ACCCCCTGAG 2400

GGAGATGCTA CTAAAAACAC CCTGGTACGA CCCAAATCTC TGTTTACATC ACAGCCTGAA 2460

ATGGAAAGCA CTGCCATTAA AATGCAGAAA GATCCACTTT CACAGCCAGC TGCCACTCCC 2520

TCTCCAAAGC CAGCGCGAGC CACCCCGAGT GCCGTGAGTC CCCAGGCAGA GCAGGCACCG 2580

CCATTCCCCC CTCCACGCTC CACCTCCTCT CCCTACCATG CCAGTAACTT GCTGCAAAGG 2640

CATTTCAGCA GTTGGGCCAA ACCCAACAGC CCCACCAGGT CGACAGAAGC CGAGTCCATC 2700

CTGCACTCGG AGGGGCGGCG TCCCGACGCG AAACCCAAAC GCTGGATATC GTTCAAGAGC 2760

TTCTTCCGCC GCAGGAAAGC TGACGATGAG GAGGAGAGAG AGAAGGAGAG GGAGAAAGGG 2820

AAGCTGGTGG GTCTGGATGG AACTGTTATA CACATGCTCC CCCCGCCTCC AGTGCAGCGG 2880

CACCACTGGT TCAGCGAGGC CAAGTCGGAC TCCAGCGAGA AGCCCTCGAT CGTTTTCATG 2940

TACAGGTGCG ACCCGGCACA GGGGGAGCCG AGGGCTGAGC TCCCACACCA GGCTGGGCTG 3000

GACTCTGCTA TCGCAGAGGC ACTGGCAAAG GACAAGGGAG AAACGCAGGA AAAGCCTCCA 3060

GAGAGCTCGG AACAAAACAT TGCCGGCCAT TCCTCACCAC CTCAGGCTCC CAAGAAAATC 3120

CCCAGTCAAG TGCCTGATGA CCCGGCCCTG GAGGAGCTGT CCCCTCGTGT CCCCAGAGCT 3180

GTGTTTGTCA AGCAGGACAA TGGGGGCAGC GCCTCGGTCA TCCCGGTCTC GGCCGCCCGC 3240

GCGCCGCCGG CCGAGGAGGA GAAAGAAGAA GCTCCAAACT CTCCTGATAT CAGTACCTGC 3300

AGTGCTACCT ACAGCAATTT AGGGCAGTCC AGAGCAGCCA TGATCCCTCC AAAGCAGCCC 3360

AGGCAACCCA AGGGAGCTTT GGATGATGCC ATTGCCTTTG GAGGGCTGGC AGACCAGGAG 3420

ACAGTGAACA GCCTGCAGCC AACACCACCT CCACTGCCAA AGAAAACAAT TCTGAGAGCT 3480

AACACAGAGC CAACTCCCCG AGATCTCCAG AAGCAGGCTC TGGAGAACAA CCTGTGCATC 3540

ATGGCCAACC CCACCTATGA CATTGACACC AACTGGGAAG CAAGCAGCGC CTGTTCCTCG 3600

GTCAGCCTGG AGCTCAAGGT CCTGGATAAC GAGTCGGGAG ATTCCTTGGA CAGGCCGACA 3660

GAGAAACTGA GGGCAGCCAC CTCGGCGACG AACAGCGTCT CCAGCCTGAC CACTCTCAGC 3720

GTTAAGGAGC GCTGCTCCAA CAGCATGGAG TCCCTGACGG GGCGGCGCCT CGCGCAGGCC 3780

AGGCAGGGCC GCGGCGTGCA GAAGCCACAG AGACAAGCAC TTTACCGAGG CATCGAGAAC 3840

AGGGAGGAGG TGGTGGGCAA GATCCGGAGC CTGCACGCGG ATTCGCTGAA GAAGCTGGCG 3900

CTGAGGTGTG AGGACCTGTT CATGGCCGGG CAGAAGGACC AGCTGCGCTT CGGGGTGGAC 3960

AGCTGGTCGG ATTTCCGGCT CACCAGCGAC AAGCCGTGCT GCGAGGCGGG TGATGCCGTC 4020

TACTACCCCG CCTCCTACGC CAAGGATCCC CTCAACAACT ACGCGGTCAA GATTTGTAAG 4080

AGCAAGGCTA AGGAATCGCA GCAGTATTAC CACAGCCTGT CTATCCGGCA GAGCCTGGCT 4140

ATCAACTTCA ACATCCAGCA GGACTGTGGC CATTTCCTTG CTGAAGTGCC AGTTCGCCTC 4200

CTGCCGTGGG AGGATGATGA CGCGCCGGAC GTGGAAGAAG AGCGGGAAGA AGAGGAGAAA 4260

GAAGCTGAGC AGAAGAGCAG AGACGCTGCT TCCAGCCCCG AGGCCTCCCG CAGGGACAGC 4320

CCCAGCAGGC AGGGCACCAC CAGCAAGCCC CGCAGCCGCG TGGTGGTGAT CACACGGGAG 4380

GTCCCGCAGC TGACGGTGGC CGACTTCGTG CGGGAGTCCG CGCCCCGCCA CAGCAAGAGC 4440

CCCGACCTGT ATGAGAGACA GGTCTGCCTG CTGCTCCTGC AGCTGTGCCT GGGCCTCGAG 4500

CACCTGAAGC CCTACCACAT CACACACTGT GACCTGCGCT TGGAGAACCT GCTGTTGGTT 4560

CACTCCAGAC CGGGAGGAAG CGCCCTGAGC CCCGAGGCCA CAGAACCCAA TCCCAACACT 4620

GCCTGCCCGG CCAGATTAAT TGTGAGCAAC TTCTCCCAGG CCAAGCAGAA GAGTCATATG 4680

GTGGATCCTG AGGTCCTGCG GGATCAGTCC CGCCTGGCTC CAGAAATCAT CACTGCAACA 4740

CAGTACAAGA AGTGTGATGA GTTCCAGACT GGCATCCTCA TCTATGAAAT GCTGCACTTA 4800

CCCAACCCCT TTGATGAGAA TCCAGAGCTG AAAGAGAAAG AATACACTTG TGCTGATCTG 4860

CCCAAGATAC CTTGCCGTTC CCTCTACTCT CAAGGGCTTC AACAACTTGC CAGCTGCCTG 4920

CTGAATCCCA ACCCTTCAGA GAGGATCTTG ATATCAGAAG CCAAAGGAAT CCTTCAGTGT 4980

TTGCTTTGGG GTCCACGTGA GGACTTGTTC CATGCTCTCA GTACATCTTC CAACCCCTCA 5040

CGGAGAGATG CTATACTTCA GAACTGGCTC GATATAAAAA GGACGCTGCT GATGATCAAG 5100

TTTGCAGAGA AGTCCTTGGA GAGGGACTGT GGAATTATTC TGGAAGACTG GCTTTGTTGT 5160

CAGTATCTGG CTTTTGCCAC TACAGACTCA CTTCATCGCA TTGTGAGACT CATGAAGCAG 5220

CACTAG 5226

Domain Profile

S: 1     ltsdkpcceagdavyytasyakdplsnyavkickskekksqsy.....vrqslpvhfniq  55

         ltsdkpcceagdavyy asyakdpl+nyavkicksk+k+sq+y     +rqsl++ fniq

Q: 1327  LTSDKPCCEAGDAVYYPASYAKDPLNNYAVKICKSKAKESQQYyhslsIRQSLAINFNIQ  1386

         79**********************************************************

S: 56    qdcGhflaevpsrlla..dpdapekd....................pkpasetepsake.  92

         qdcGhflaevp rll+  d dap+ +                    p      e+s+++

Q: 1387  QDCGHFLAEVPVRLLPweDDDAPDVEeereeeekeaeqksrdaassP------EASRRDs  1440

         ****************8766666655778899999988886555442......3333334

S: 93    ..........rdhvvvitrevphltvadfvrdslashraepelyerrvcllllqlcsGle  142

                   r+ vvvitrevp+ltvadfvr+s+ +h ++p+lyer+vcllllqlc Gle

Q: 1441  psrqgttskpRSRVVVITREVPQLTVADFVRESAPRHSKSPDLYERQVCLLLLQLCLGLE  1500

         4455688888**************************************************

S: 143   hlkeygvihrdlrlenlllvhlqpqagaaqaaapaepaptsaapsaapaattasqegpre  202

         hlk+y+++h+dlrlenlllvh +p +g+a ++  +ep p +a+p

Q: 1501  HLKPYHITHCDLRLENLLLVHSRP-GGSALSPEATEPNPNTACP----------------  1543

         ************************.9******************................

S: 203   kqltrlivsnflkakqksgglvdlqikkdqarlapeivsasqykkfdefqtGiliyellh  262

            +rlivsnf++akqks ++vd+++++dq+rlapei++a+qykk+defqtGiliye+lh

Q: 1544  ---ARLIVSNFSQAKQKS-HMVDPEVLRDQSRLAPEIITATQYKKCDEFQTGILIYEMLH  1599

         ...8**************.*****************************************

S: 263   lpnpfevraelkereyrredlprlpllslysrGlqqlasllleadpikriliseakrvl  321

         lpnpf++++elke+ey+ +dlp++p +slys+Glqqlas+ll+++p++riliseak++l

Q: 1600  LPNPFDENPELKEKEYTCADLPKIPCRSLYSQGLQQLASCLLNPNPSERILISEAKGIL  1658

         *********************************************************98

Domain Sequence
(FASTA)

LTSDKPCCEA GDAVYYPASY AKDPLNNYAV KICKSKAKES QQYYHSLSIR QSLAINFNIQ 60

QDCGHFLAEV PVRLLPWEDD DAPDVEEERE EEEKEAEQKS RDAASSPEAS RRDSPSRQGT 120

TSKPRSRVVV ITREVPQLTV ADFVRESAPR HSKSPDLYER QVCLLLLQLC LGLEHLKPYH 180

ITHCDLRLEN LLLVHSRPGG SALSPEATEP NPNTACPARL IVSNFSQAKQ KSHMVDPEVL 240

RDQSRLAPEI ITATQYKKCD EFQTGILIYE MLHLPNPFDE NPELKEKEYT CADLPKIPCR 300

SLYSQGLQQL ASCLLNPNPS ERILISEAKG IL 332

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005925	; C:focal adhesion
GO:0005524	; F:ATP binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0016477	; P:cell migration
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013