EPS-TAG-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	287.2	1.2E-85	23	293	271

Status

Unreviewed

Ensembl Protein

ENSTGUP00000003910

UniProt Accession

H0Z025;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1B

Gene Synonyms/Alias

PPM1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000003793	ENSTGUP00000003910	ENSTGUT00000003952

Organism

Taeniopygia guttata

Functional Description

Protein Length

425

Protein Sequence
(FASTA)

MGAFLDKPKT EKHNAHGAGN GLRYGLSSMQ GWRVEMEDAH TAVVGIPHGL EDWSFFAVYD 60

GHAGSRVANY CSTHLLEHIT NNEDFRATEK PGSALEPSVE NVKSGIRTGF LKIDEYMRNF 120

ADLRNGMDRS GSTAVGVMIS PEHVYFINCG DSRAVLYRNG QVCFSTQDHK PCNPREKERI 180

QNAGGSVMIQ RVNGSLAVSR ALGDYDYKCV DGKGPTEQLV SPEPEVCEIL RAEEDEFIIL 240

ACDGIWDVMS NEELCEYVKS RLEVSDDLET VCNWVVDTCL HKGSRDNMSI VLVCFSNAPK 300

VSEEAVKKDA ELDKYLESRV EEIMEKAGEE GMPDLAHVIR ILTAENIPNL PPGGGLAGKR 360

NIIENVYTRL NPHRDNEGEP GAAEEGGTQG RLAEALRQMR INHRGHYRHL LEELLGGFRL 420

AQLRG 425

Nucleotide Sequence
(FASTA)

ATGGGTGCAT TTTTGGATAA ACCAAAAACT GAAAAACATA ATGCTCATGG TGCAGGGAAT 60

GGCTTGCGTT ACGGCCTCAG CAGTATGCAG GGATGGAGAG TGGAAATGGA AGATGCTCAC 120

ACAGCTGTTG TAGGTATTCC CCATGGCTTA GAAGACTGGT CCTTTTTTGC TGTCTATGAT 180

GGTCACGCGG GATCTCGTGT TGCAAATTAC TGCTCCACTC ACTTATTAGA ACACATCACT 240

AACAATGAAG ACTTTAGGGC GACAGAAAAA CCTGGATCTG CTCTTGAACC TTCAGTGGAA 300

AATGTCAAGA GTGGAATCAG AACTGGCTTT TTGAAAATTG ATGAGTATAT GCGCAATTTT 360

GCAGACCTCA GAAATGGCAT GGACAGAAGT GGCTCTACAG CAGTGGGAGT TATGATTTCA 420

CCTGAGCATG TATACTTTAT CAACTGTGGT GATTCACGTG CTGTTCTCTA TAGGAATGGA 480

CAAGTCTGTT TTTCAACACA GGATCACAAA CCTTGCAACC CGAGGGAGAA AGAGCGAATC 540

CAGAATGCAG GAGGCAGTGT AATGATTCAG CGTGTTAATG GTTCCTTGGC AGTTTCTCGA 600

GCTCTGGGAG ACTATGACTA CAAATGTGTT GATGGTAAAG GCCCTACAGA ACAACTTGTT 660

TCTCCAGAGC CTGAGGTGTG TGAAATTTTA AGGGCAGAAG AAGATGAGTT TATCATCCTG 720

GCTTGTGATG GCATCTGGGA TGTAATGAGC AATGAAGAGC TCTGTGAATA TGTAAAGTCT 780

AGACTTGAAG TATCAGATGA CCTGGAAACA GTGTGCAATT GGGTAGTGGA CACTTGTTTA 840

CATAAGGGGA GTCGTGATAA CATGAGTATT GTATTAGTTT GTTTTTCAAA TGCTCCTAAG 900

GTCTCAGAGG AGGCAGTGAA AAAAGATGCT GAGTTGGATA AGTACTTGGA ATCACGGGTT 960

GAAGAAATTA TGGAAAAAGC AGGTGAAGAA GGAATGCCTG ATCTTGCTCA TGTTATTCGT 1020

ATTTTAACTG CAGAGAATAT CCCTAATTTA CCACCAGGAG GTGGTTTAGC TGGCAAGCGT 1080

AATATTATTG AAAATGTGTA TACTAGGCTG AATCCACACA GAGACAATGA GGGGGAGCCC 1140

GGCGCGGCCG AGGAAGGCGG AACGCAGGGG AGGTTGGCGG AGGCGCTGAG GCAGATGCGG 1200

ATTAATCACA GGGGCCACTA CCGCCACCTG CTGGAGGAGC TGCTGGGCGG GTTCCGCCTG 1260

GCGCAGCTGC GGGGC 1275

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++s++g+r emeda+t++ ++    + +d ++ff+vyDGh+gs+va++cs++l e++

Q: 23    RYGLSSMQGWRVEMEDAHTAVVGIPH--GLED-WSFFAVYDGHAGSRVANYCSTHLLEHI  79

         69****************98555444..4434.***************************

S: 62    aeele.........sseseerkvkkalakaFlstdeelkvleeksldidksGstavvali  112

         +++ +         + e++ ++vk+ ++++Fl++de ++++ + ++ +d+sGstav ++i

Q: 80    TNNEDfratekpgsALEPSVENVKSGIRTGFLKIDEYMRNFADLRNGMDRSGSTAVGVMI  139

         ***99*********99********************************************

S: 113   kdsklyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvL  172

         +++++y++n+GdSravL rng+++  ++dHkp +++E+eRi++aggsv+ +   Rv+G+L

Q: 140   SPEHVYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSL  196

         ***************************************************...******

S: 173   avsRalGdlylk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavs  223

         avsRalGd+++k         ++v+pePev ++ + +edef+iLa+DG+wdv+snee+++

Q: 197   AVSRALGDYDYKcvdgkgpteQLVSPEPEVCEILRAEEDEFIILACDGIWDVMSNEELCE  256

         ************************************************************

S: 224   lvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

         +v+++le +++++++++ +v+++l++gs+dn+s+++v

Q: 257   YVKSRLEVSDDLETVCNWVVDTCLHKGSRDNMSIVLV  293

         ********************************98875

Domain Sequence
(FASTA)

RYGLSSMQGW RVEMEDAHTA VVGIPHGLED WSFFAVYDGH AGSRVANYCS THLLEHITNN 60

EDFRATEKPG SALEPSVENV KSGIRTGFLK IDEYMRNFAD LRNGMDRSGS TAVGVMISPE 120

HVYFINCGDS RAVLYRNGQV CFSTQDHKPC NPREKERIQN AGGSVMIQRV NGSLAVSRAL 180

GDYDYKCVDG KGPTEQLVSP EPEVCEILRA EEDEFIILAC DGIWDVMSNE ELCEYVKSRL 240

EVSDDLETVC NWVVDTCLHK GSRDNMSIVL V 271

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013