EKS-TAG-00148

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00148

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	284.8	5.8E-85	1	253	253

Status

Unreviewed

Ensembl Protein

ENSTGUP00000003961

UniProt Accession

H0Z075;

Protein Name

Protein Synonyms/Alias

Gene Name

AAK1

Gene Synonyms/Alias

AAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000003831	ENSTGUP00000003961	ENSTGUT00000004004

Organism

Taeniopygia guttata

Functional Description

Protein Length

899

Protein Sequence
(FASTA)

GGFAIVFLVR TSNGVKCALK RMYVNNEYDL QVCKREIQIM RDLSGHKNIV GYIDSSINSV 60

SSGDVWEVLI LMDFCRGEAV PKLPGGCSEL SKARAGAGEV GCVDSADGIV LHDLMSILGD 120

VTVENILLHD RGHYVLCDFG SATNKFQNPQ TEGVNAVEEE IKKYTTLSYR APEMVNLYSG 180

KLITTKADIW ALGCLLYKLC YFTLPFGESQ VAICDGNFTI PDNSRHSQDM HCLIRYMLEP 240

DPDKRPDIYQ VSYFAFKLAK KDCPVQNVQN SPIPAKLPDP VKASEAAAKK SQPKARLTDP 300

IPTTETSIAP RQRPKAGQTQ PNPGILPIQP ALTPRKRATA QAAIQPQGER VAQPSLPAST 360

PQPKAAPQQP PAQPQAKPAA APQAPPQAPS AQPQATPQHQ QQLFLKQQLL QQQQQQQQQA 420

ALPAAQQQQM MQAQQVGVGA GFITSVCPPH LQPLVSQFPV VQQGAPVQQQ QLMQNYYQQQ 480

QQQQLLAQQA AMQQKTTAAA AAQQKQQPQA QPGTAPPPQP QEQGQGHCAF LPWQAQVQAQ 540

RQQQAQGQKL GSLTPPSSPK AQRAGHRRIL SDVTHSAVFG VPASKSTQLL QAAAAEASLN 600

KSKSASTTPS GSPRTSQQNV YNPPDMSTWN PFDDDNFSKL TAEELLNKDF AKLGDGKAPE 660

KAGSSTENLI PGFQPAAPAA PADAFGGSSF PAGPAEKTKD ILSLDSSPAL LTVPDPFIPL 720

PLSDTPEKLI EGLKSPEPAL LLPELLPLAD PFGSTADTVN GKAAVAVESL IPGLEAPLPQ 780

RLVSQSDSVA SNRTDSLTGE DSLLDCSLLS NPAADLLDEF APVAFTAQPH KESKDTNLIS 840

GFDAPEGSEK VTEDEFDPIP VLISKNSQGG HSRNNSGSSE SSLPNIARSL LLVDQLIDL 899

Nucleotide Sequence
(FASTA)

GGTGGCTTTG CAATCGTGTT CCTGGTGAGG ACGAGCAATG GGGTGAAGTG TGCCCTGAAG 60

AGGATGTACG TCAATAACGA GTACGACCTG CAGGTCTGCA AGAGAGAGAT CCAGATCATG 120

CGGGATCTGT CTGGCCACAA GAACATTGTG GGCTACATCG ACTCCAGCAT CAACTCAGTC 180

AGCAGCGGGG ACGTGTGGGA AGTGCTGATC CTCATGGACT TCTGCCGGGG TGAAGCTGTC 240

CCTAAGCTGC CAGGAGGCTG TTCTGAGCTC AGCAAAGCCA GGGCTGGGGC TGGAGAAGTG 300

GGCTGTGTTG ACTCTGCTGA TGGGATTGTG TTACATGACT TGATGTCTAT TTTAGGAGAC 360

GTGACAGTTG AAAACATCCT GCTGCATGAC CGTGGCCACT ACGTCCTGTG TGACTTTGGG 420

AGTGCTACCA ACAAATTCCA GAACCCTCAA ACAGAGGGGG TGAACGCAGT CGAGGAGGAG 480

ATCAAGAAGT ACACGACGTT GTCCTACAGA GCACCAGAGA TGGTGAACCT GTACAGTGGC 540

AAACTCATCA CTACAAAAGC TGACATTTGG GCCCTGGGCT GTTTGCTGTA CAAGCTGTGC 600

TACTTCACCT TGCCCTTTGG GGAGAGCCAG GTGGCCATTT GTGACGGCAA CTTCACCATC 660

CCGGACAACT CGCGGCACTC GCAGGACATG CACTGCCTCA TCCGCTACAT GCTCGAGCCA 720

GACCCTGATA AGAGGCCTGA CATTTATCAG GTGTCCTACT TTGCATTCAA ACTGGCCAAG 780

AAGGACTGCC CGGTGCAGAA CGTCCAGAAC TCTCCAATCC CTGCTAAACT CCCAGACCCA 840

GTTAAAGCAA GTGAAGCTGC TGCAAAGAAG AGTCAACCAA AGGCCAGGCT CACAGACCCC 900

ATCCCTACCA CAGAAACGTC CATAGCACCC CGCCAGCGAC CTAAAGCAGG ACAGACCCAG 960

CCCAACCCTG GAATTCTGCC CATCCAGCCA GCCCTGACGC CCAGGAAGAG AGCCACAGCC 1020

CAGGCAGCCA TTCAGCCGCA GGGTGAGCGA GTTGCCCAGC CCTCGCTCCC TGCCAGCACC 1080

CCCCAGCCAA AAGCAGCCCC CCAGCAGCCT CCAGCCCAGC CCCAGGCCAA GCCGGCAGCA 1140

GCGCCCCAGG CACCGCCCCA GGCCCCCTCG GCACAGCCCC AGGCCACCCC TCAGCATCAG 1200

CAGCAGCTTT TCCTGAAGCA GCAGCTCCTG CAGCAGCAAC AGCAGCAGCA GCAGCAGGCT 1260

GCCCTTCCAG CAGCACAGCA GCAGCAGATG ATGCAGGCAC AGCAGGTGGG TGTGGGTGCT 1320

GGGTTCATCA CATCTGTGTG TCCACCACAC CTCCAACCTC TTGTTTCCCA GTTCCCAGTG 1380

GTGCAGCAAG GAGCGCCCGT GCAGCAGCAG CAGCTGATGC AGAACTACTA CCAGCAGCAG 1440

CAGCAGCAGC AGCTGCTGGC CCAGCAGGCA GCTATGCAGC AGAAGACCAC AGCAGCAGCA 1500

GCAGCTCAGC AGAAGCAGCA GCCCCAGGCC CAGCCTGGCA CGGCACCACC GCCGCAGCCA 1560

CAGGAGCAGG GGCAAGGTCA CTGTGCTTTC CTCCCCTGGC AGGCGCAGGT GCAGGCTCAG 1620

AGGCAGCAGC AGGCACAGGG GCAGAAGCTG GGCTCCCTCA CGCCGCCGTC CTCGCCCAAG 1680

GCGCAGCGCG CGGGGCACCG CCGCATCCTC AGCGACGTCA CCCACAGCGC CGTGTTCGGC 1740

GTGCCTGCCA GCAAATCCAC CCAGCTGCTG CAGGCTGCCG CCGCTGAGGC CAGCCTCAAC 1800

AAGTCCAAAT CTGCTTCCAC CACGCCCTCG GGCTCGCCAA GGACCTCGCA GCAGAATGTC 1860

TACAACCCCC CCGACATGTC CACGTGGAAC CCCTTTGATG ATGACAACTT CTCCAAGCTG 1920

ACAGCCGAGG AGCTGCTGAA CAAGGACTTT GCAAAGCTGG GGGATGGGAA AGCTCCAGAA 1980

AAGGCAGGCA GCTCCACAGA GAACCTGATC CCAGGTTTCC AGCCCGCTGC GCCCGCGGCC 2040

CCGGCGGATG CCTTCGGTGG CTCCTCCTTC CCTGCTGGGC CAGCAGAAAA AACGAAAGAC 2100

ATTCTGAGTT TGGACTCTAG CCCTGCTCTT CTGACTGTGC CTGATCCTTT CATCCCTCTC 2160

CCGTTATCCG ACACCCCAGA AAAACTGATT GAGGGCCTCA AATCTCCGGA GCCTGCGCTC 2220

CTGCTCCCCG AGCTGCTGCC TCTGGCTGAC CCCTTTGGCA GCACGGCAGA CACGGTCAAT 2280

GGCAAAGCTG CCGTGGCTGT GGAGAGCCTG ATCCCGGGGC TGGAGGCCCC GCTGCCCCAG 2340

CGCCTCGTGT CCCAGAGCGA CTCCGTGGCC TCCAACAGAA CAGACTCTCT CACTGGGGAA 2400

GACTCTCTGC TTGACTGTTC TCTGCTCTCT AACCCTGCTG CTGACCTCCT GGATGAGTTT 2460

GCTCCTGTAG CTTTCACAGC TCAGCCTCAC AAAGAATCAA AAGATACTAA CCTGATATCA 2520

GGCTTTGATG CTCCTGAGGG CTCTGAAAAA GTGACAGAAG ATGAGTTTGA CCCAATTCCA 2580

GTGTTGATAT CCAAAAATTC ACAAGGTGGG CATTCTAGAA ACAACAGTGG AAGCTCTGAG 2640

TCCAGTCTTC CCAACATAGC CAGGTCTTTG CTGCTGGTGG ATCAGCTCAT AGACCTGTAG 2700

Domain Profile

S: 10    GGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghknivklvdssvke  69

         GGfa+v+l++ +s+g k+alKr++vn+e dl+ +krEi+im++lsghkniv ++dss+++

Q: 1     GGFAIVFLVR-TSNGVKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINS  59

         9*********.99***********************************************

S: 70    ekdngskevlllleyckkgslvdllnkrlekgelseaeilki.lldvtravaalHalsvp  128

          ++++++evl+l+++c+ g+ v  l    ++ +   a   ++  +d + ++  lH

Q: 60    VSSGDVWEVLILMDFCR-GEAVPKLPGGCSELSKARAGAGEVgCVDSADGI-VLH--DLM  115

         ***9*************.566666665555432223333333134566666.588..777

S: 129   liHRDlkveNillsdegelvlcDlGSattaileveskqelsalqeeieknttlsyrsPEl  188

          i  D++veNill+d+g++vlcD+GSat+++++++ +++++a++eei+k+ttlsyr+PE+

Q: 116   SILGDVTVENILLHDRGHYVLCDFGSATNKFQNPQ-TEGVNAVEEEIKKYTTLSYRAPEM  174

         8899*******************************.9***********************

S: 189   idlysnlvideksDiWaLGcllYklcffesPfeesvklailngkysiPensryseklksl  248

         ++lys++ i++k+DiWaLGcllYklc+f+ Pf+es ++ai++g+++iP+nsr+s+++++l

Q: 175   VNLYSGKLITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGNFTIPDNSRHSQDMHCL  233

         ***********************************.************************

S: 249   ikkmlevdpeeRptiaqvle  268

         i++mle+dp++Rp+i+qv++

Q: 234   IRYMLEPDPDKRPDIYQVSY  253

         ******************87

Domain Sequence
(FASTA)

GGFAIVFLVR TSNGVKCALK RMYVNNEYDL QVCKREIQIM RDLSGHKNIV GYIDSSINSV 60

SSGDVWEVLI LMDFCRGEAV PKLPGGCSEL SKARAGAGEV GCVDSADGIV LHDLMSILGD 120

VTVENILLHD RGHYVLCDFG SATNKFQNPQ TEGVNAVEEE IKKYTTLSYR APEMVNLYSG 180

KLITTKADIW ALGCLLYKLC YFTLPFGESQ VAICDGNFTI PDNSRHSQDM HCLIRYMLEP 240

DPDKRPDIYQ VSY 253

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0045747	; P:positive regulation of Notch signaling pathway
GO:0050821	; P:protein stabilization
GO:2000369	; P:regulation of clathrin-mediated endocytosis
GO:0032880	; P:regulation of protein localization

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013