EKS-TAG-00298

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00298

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	368.0	2.9E-110	225	518	294

Status

Unreviewed

Ensembl Protein

ENSTGUP00000004109

UniProt Accession

H0Z0M2;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000003987	ENSTGUP00000004109	ENSTGUT00000004154

Organism

Taeniopygia guttata

Functional Description

Protein Length

557

Protein Sequence
(FASTA)

MGYWRRPGLL PLLLLSLSWG ASARRSLKTN LCKWCDSTAP ACKEKLCYSN CNLNSYCEDP 60

YEICVAIWRQ DNESIRISTL CHNPHHPIEN LMVPNYNTSR CIMSHQPSED GIIYICGCVD 120

EQECNDKLIF ENHTNGYSML QSKEVIPVAA ISLLPPLLVA VMITVIFYLC RTQKRHKRAK 180

AWGGKQGQPP VLPEQGKAAE REEKLTVLMD ESPASSSHPA ELLPIELDEM VGKGQFAEVW 240

RAKLSHSRSG QYETVAVKIF PCEEYSSWKN ESQIFTDTSL RHDSVLQFLT AEDRGTGPRR 300

EYWLITAYHS RGNLKDYLSH HVLSWMDLQK MAGSLVSGVA HLHSDYTACG RPKIPIAHRD 360

IKSTNVLVKD EQECVLCDFG IAIRLDPSLT VDDFANSGQV GTARYMAPEV LESRVNLEDL 420

ESFKQMDVYS MALVLWEMAS RCEVVGEVKN YELPFGSKVQ EQPCVDTMRD IVLHGRGRPE 480

IPSSWLVHQG MRFLCDTITE CWDHDPEARL TAHCVAERFN LMAQMDCDDI LNNNMDNEAS 540

KTASPGGELQ DSDGSRN 557

Nucleotide Sequence
(FASTA)

ATGGGCTACT GGAGGAGACC GGGTCTGCTT CCCTTACTGC TGCTCTCCTT GTCCTGGGGT 60

GCCAGCGCCC GGCGCAGCCT CAAGACCAAC CTGTGCAAGT GGTGCGACTC CACCGCTCCG 120

GCCTGCAAGG AGAAGCTGTG CTACAGCAAC TGCAACCTCA ACTCCTACTG CGAGGACCCC 180

TACGAGATCT GCGTGGCAAT ATGGAGACAG GACAACGAGA GCATCAGGAT CAGCACGCTC 240

TGCCACAACC CCCACCACCC CATCGAAAAC CTCATGGTCC CCAACTACAA CACCTCCCGC 300

TGCATCATGA GCCACCAGCC CAGCGAGGAT GGCATCATCT ACATCTGTGG CTGTGTGGAT 360

GAGCAGGAGT GCAACGACAA ACTCATCTTT GAAAACCACA CCAATGGCTA CTCCATGCTG 420

CAGAGCAAAG AGGTGATCCC AGTGGCTGCC ATCAGCCTGC TGCCCCCGCT GCTGGTGGCG 480

GTGATGATCA CGGTGATATT TTACCTCTGC CGCACGCAGA AGCGACACAA GAGAGCCAAG 540

GCGTGGGGTG GGAAACAGGG ACAGCCCCCA GTGCTGCCGG AGCAGGGGAA GGCAGCTGAG 600

CGGGAGGAGA AGTTGACCGT GCTGATGGAT GAGAGCCCGG CCAGCAGCAG CCACCCCGCT 660

GAGCTGCTCC CCATCGAGCT GGACGAGATG GTGGGCAAGG GGCAGTTCGC GGAGGTCTGG 720

AGAGCCAAGC TGAGCCACAG CCGCTCCGGG CAGTACGAGA CCGTGGCCGT GAAGATCTTC 780

CCCTGCGAGG AATACTCCTC CTGGAAGAAC GAGAGCCAGA TCTTCACCGA CACCAGCCTC 840

AGGCACGACA GCGTCCTGCA GTTCCTCACT GCTGAGGACC GGGGCACAGG GCCCCGCCGG 900

GAGTACTGGC TCATCACCGC CTACCACAGC CGAGGCAACC TCAAGGACTA CCTCTCCCAC 960

CACGTGCTGA GCTGGATGGA CCTGCAGAAG ATGGCTGGGT CCCTGGTGAG TGGGGTGGCC 1020

CACCTTCACA GCGACTACAC CGCATGCGGC CGCCCGAAAA TCCCCATCGC CCACCGCGAC 1080

ATCAAGAGCA CAAACGTCCT GGTGAAGGAC GAGCAGGAGT GCGTGCTCTG CGACTTCGGC 1140

ATCGCCATAC GCCTTGACCC CTCCCTGACA GTGGATGACT TTGCCAACAG TGGGCAGGTG 1200

GGCACTGCCA GGTACATGGC CCCAGAGGTC CTGGAGTCCA GAGTGAACCT GGAAGACCTG 1260

GAGTCTTTTA AGCAGATGGA TGTCTACTCC ATGGCCCTTG TTTTGTGGGA AATGGCCTCC 1320

AGATGTGAAG TGGTAGGAGA GGTAAAGAAT TATGAGCTAC CTTTTGGGTC AAAAGTCCAG 1380

GAGCAGCCTT GTGTGGACAC CATGAGGGAC ATCGTGCTGC ATGGCAGAGG CCGGCCCGAG 1440

ATCCCAAGCA GCTGGCTGGT GCACCAGGGA ATGCGCTTCC TGTGCGACAC CATCACGGAG 1500

TGCTGGGACC ACGACCCCGA GGCTCGGCTC ACCGCCCACT GCGTGGCTGA GCGCTTCAAC 1560

CTGATGGCAC AGATGGATTG TGATGACATC CTCAACAACA ACATGGACAA TGAGGCCAGC 1620

AAAACAGCTT CTCCAGGTGG GGAGCTCCAG GACAGTGATG GGAGCAGAAA C 1671

Domain Profile

S: 1     lklleligkGrygeVwkaklrg......eevAvKifstedeaswkrEkeiyqtvllrhen  54

         ++l e++gkG+++eVw+akl++      e+vAvKif+ e+ +swk+E++i++ + lrh++

Q: 225   IELDEMVGKGQFAEVWRAKLSHsrsgqyETVAVKIFPCEEYSSWKNESQIFTDTSLRHDS  284

         6899****************999999999*******************************

S: 55    ilqfiaadkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHe  114

         +lqf++a+ + ++ + e++l+t+yh +g+L dyL++++l++ +l ++a sl+sG+ahLH+

Q: 285   VLQFLTAEDRGTGPRREYWLITAYHSRGNLKDYLSHHVLSWMDLQKMAGSLVSGVAHLHS  344

         ************************************************************

S: 115   eivgtkgkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtk  174

         +  + +g+ K  iaHRD+ks N+lvk+++ c+++D+G+a++l+ + ++ d a++ qvGt

Q: 345   DY-TACGRPKIPIAHRDIKSTNVLVKDEQECVLCDFGIAIRLDPSLTVDDFANSGQVGTA  403

         *5.66799****************************************************

S: 175   RYmaPEvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsd  234

         RYmaPEvle+++nl+d+e+fk++DvYs++LvlWE+asRce   +ev++y+lpf ++v+++

Q: 404   RYMAPEVLESRVNLEDLESFKQMDVYSMALVLWEMASRCEV-VGEVKNYELPFGSKVQEQ  462

         ****************************************9.999***************

S: 235   PsleemkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkr  290

         P+++ m+++v++ + rP+ip++w  ++ ++ l+++++ecWd+dpeaRlta++v++r

Q: 463   PCVDTMRDIVLHGRGRPEIPSSWLVHQGMRFLCDTITECWDHDPEARLTAHCVAER  518

         *****************************************************987

Domain Sequence
(FASTA)

IELDEMVGKG QFAEVWRAKL SHSRSGQYET VAVKIFPCEE YSSWKNESQI FTDTSLRHDS 60

VLQFLTAEDR GTGPRREYWL ITAYHSRGNL KDYLSHHVLS WMDLQKMAGS LVSGVAHLHS 120

DYTACGRPKI PIAHRDIKST NVLVKDEQEC VLCDFGIAIR LDPSLTVDDF ANSGQVGTAR 180

YMAPEVLESR VNLEDLESFK QMDVYSMALV LWEMASRCEV VGEVKNYELP FGSKVQEQPC 240

VDTMRDIVLH GRGRPEIPSS WLVHQGMRFL CDTITECWDH DPEARLTAHC VAER 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Latimeria chalumnae"; ?>Meleagris gallopavo"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Tetraodon nigroviridis"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0043235	; C:receptor complex
GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005026	; F:transforming growth factor beta receptor activity, type II
GO:0023014	; P:signal transduction by phosphorylation
GO:0007179	; P:transforming growth factor beta receptor signaling pathway

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR017194	; Transform_growth_fac-b_typ-2.
IPR015013	; Transforming_GF_b_rcpt_2_ecto.

Pfam

PF08917	; ecTbetaR2; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013