EKS-TAG-00495

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00495

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	530.9	5.4E-160	23	280	258

Status

Unreviewed

Ensembl Protein

ENSTGUP00000004661

UniProt Accession

H0Z271;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000004480	ENSTGUP00000004661	ENSTGUT00000004710

Organism

Taeniopygia guttata

Functional Description

Protein Length

352

Protein Sequence
(FASTA)

PSTPTDNINL GPSANPNAKP TDFDFLKVIG KGSFGKVLLA KRKCDGTFYA VKVLHKKTIL 60

KKKEQNHIMA ERNVLLKNVK HPFLVGLHYS FQTSEKLYFV LDYVNGGELF FHLQRERCFR 120

EPRARFYAAE VASAVGYLHS LNIIYRDLKP ENILLDCQGH IVLTDFGLCK EGMEQEETTS 180

TFCGTPEYLA PEVLKKQPYD RTVDWWCLGA VLYEMLFGLP PFYSRDVSQM YDNILHKPLQ 240

IQGTKTVAAC DILQGLLHKD QKRRLGAKTD FLEIKNHVFF SPINWDDLYH KRITPPFNPN 300

VAGPADLRHF DPEFTQEAIS ASITRTPDLA ASSSSASDAF LGFSYASTEE DF 352

Nucleotide Sequence
(FASTA)

CCTTCAACAC CAACTGACAA CATCAACCTC GGACCTTCTG CTAACCCCAA TGCCAAGCCA 60

ACAGACTTTG ACTTCCTGAA GGTTATTGGC AAAGGAAGCT TTGGAAAAGT TCTCCTGGCC 120

AAACGCAAGT GCGATGGGAC TTTTTATGCA GTGAAAGTCT TGCATAAGAA AACCATCCTC 180

AAGAAAAAAG AGCAAAACCA CATCATGGCA GAACGCAACG TGCTTCTGAA AAATGTCAAG 240

CACCCCTTCC TTGTGGGACT CCACTATTCC TTCCAGACCT CAGAGAAGCT TTACTTTGTG 300

CTTGACTATG TAAATGGAGG AGAGCTCTTC TTCCACCTGC AAAGGGAGCG CTGTTTCCGT 360

GAGCCCCGGG CCCGGTTCTA CGCTGCAGAA GTGGCCAGTG CTGTTGGCTA CCTGCATTCC 420

CTAAACATCA TCTACAGGGA CTTAAAGCCT GAGAACATCC TCCTGGATTG CCAGGGACAC 480

ATAGTATTGA CAGACTTTGG ACTCTGCAAA GAAGGAATGG AGCAAGAGGA GACAACTTCT 540

ACCTTTTGTG GCACTCCTGA GTATCTGGCT CCTGAGGTGC TAAAGAAGCA GCCCTATGAC 600

AGGACAGTAG ACTGGTGGTG CCTGGGAGCT GTTCTCTATG AAATGCTCTT TGGACTGCCT 660

CCTTTTTACA GCCGGGATGT GTCTCAGATG TATGACAACA TTCTGCACAA GCCACTACAG 720

ATCCAAGGAA CCAAGACTGT GGCAGCTTGT GACATCCTTC AGGGACTTCT CCACAAGGAC 780

CAGAAGAGGA GGCTGGGTGC CAAAACAGAC TTTCTTGAGA TAAAGAACCA CGTATTCTTC 840

AGCCCAATAA ACTGGGATGA TTTATATCAC AAGAGGATTA CTCCTCCATT CAACCCCAAT 900

GTGGCTGGCC CAGCTGATCT GCGACACTTT GATCCTGAGT TCACCCAAGA AGCCATCTCT 960

GCCTCCATCA CCCGCACGCC TGACCTAGCA GCCAGCAGCT CCAGTGCCTC AGATGCGTTT 1020

TTAGGATTTT CATATGCATC AACTGAAGAG GACTTT 1056

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d++fyavkvl+kk+ilkkke++himaernvllknvkhp

Q: 23    FDFLKVIGKGSFGKVLLAKRKCDGTFYAVKVLHKKTILKKKEQNHIMAERNVLLKNVKHP  82

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvldyvnggelffhlqrer+f eprarfyaae+asa+gylhsln

Q: 83    FLVGLHYSFQTSEKLYFVLDYVNGGELFFHLQRERCFREPRARFYAAEVASAVGYLHSLN  142

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++gh+vltdfglcke++e+e+ttstfcgtpeylapevl+k+pydrt

Q: 143   IIYRDLKPENILLDCQGHIVLTDFGLCKEGMEQEETTSTFCGTPEYLAPEVLKKQPYDRT  202

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml+glppfysrdv++mydnil+kplq++++ +vaa+++l++ll+kd+k

Q: 203   VDWWCLGAVLYEMLFGLPPFYSRDVSQMYDNILHKPLQIQGTKTVAACDILQGLLHKDQK  262

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgak dfleiknhvff

Q: 263   RRLGAKTDFLEIKNHVFF  280

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KCDGTFYAVK VLHKKTILKK KEQNHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TSEKLYFVLD YVNGGELFFH LQRERCFREP RARFYAAEVA SAVGYLHSLN 120

IIYRDLKPEN ILLDCQGHIV LTDFGLCKEG MEQEETTSTF CGTPEYLAPE VLKKQPYDRT 180

VDWWCLGAVL YEMLFGLPPF YSRDVSQMYD NILHKPLQIQ GTKTVAACDI LQGLLHKDQK 240

RRLGAKTDFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0015459	; F:potassium channel regulator activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013