EKS-TAG-00301

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00301

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	468.5	5.3E-141	542	803	262

Status

Unreviewed

Ensembl Protein

ENSTGUP00000004917

UniProt Accession

H0Z2X5;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1

Gene Synonyms/Alias

ERN1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000004752	ENSTGUP00000004917	ENSTGUT00000004966

Organism

Taeniopygia guttata

Functional Description

Protein Length

946

Protein Sequence
(FASTA)

NTSSVTVPET LLFVSTLDGS LHAVSKRTGT IKWTLKEDPV LQVPIHVEEP AFLPDPNDGS 60

LYTLGGKNSE GLTKLPFTIP ELVQASPCRS SDGILYMGKK QDIWYVVDMT GEKQQTLTSF 120

FAESLCPSTS LLYLGRTEYT ITMYDTKKKE LRWNATYFDY AATLPDEDIK YKMSHFVSNG 180

DGLVVTVDSE SGDVLWIQNY ASPVVAFYIW QREGLRKVLH TNVGIETLRY LTFMSGEVGH 240

ITKWKYPFPK ETETKSKLTP TLYVGKYSTS LYASPSMVHE GVTVVPRGSA IPLLEGPKTE 300

GVTIEDNGEC VITPSTDVKF SGRLKEKHKL NYWNDWLLIG HHETPLSAPT KILEKFPSNL 360

PKRPENVIPA GSEKATIEEV IDIVEGSSTE GPPAAPKDIE ETPARPIPRP EAPVDSMLKD 420

MATIILSTFL LVGWVAFIIT YPMSVHQQQQ RQHQLEEKIQ LLQQQKLPFG AAGDLPPEAD 480

FLDTSCGRTE SSAASTPNLS PRASNHSAYS NISTSDVGSC LSTEQEEGDE EANRVIVGKI 540

SFNPKDVLGH GAEGTIVYRG SFDNRDVAVK RILPECFSFA DREVQLLRES DEHPNVIRYF 600

CTERDRQFQY IAIELCAATL QEYVEQKAFS HHGLQPITLL QQTTSGLAYL HSLNIVHRDL 660

KPHNILISMP NAHGKVKAMI SDFGLCKKLA VGRHSFSRRS GVPGTEGWIA PEMLSEDCKE 720

NPTYTVDIFS AGCVFYYVVS EGGHPFGKSL QRQANILLGA YSLEALDAGR HEDIVARDLI 780

EQMINMDPQK RPSASCVLKH PFFWSLEKQL QFFQDVSDRI EKESLDGPIV KQLERGGREV 840

VKMDWREHIT VPLQTDLRKF RSYKGGSVRD LLRAMRNKKH HYRELPPEVQ ETLGSIPDDF 900

VCYFTARFPR LLLHTYHAMH ICCQERLFQH YYAEDSAELS LTGDTV 946

Nucleotide Sequence
(FASTA)

AACACCAGCT CAGTAACTGT GCCAGAAACA CTGTTGTTTG TTTCAACCCT GGATGGAAGT 60

TTGCACGCTG TCAGCAAGAG GACAGGAACA ATCAAGTGGA CTTTAAAAGA AGATCCTGTC 120

CTCCAGGTGC CGATCCATGT GGAAGAGCCA GCATTTCTTC CAGACCCAAA TGATGGCAGT 180

TTGTACACAC TTGGTGGCAA GAACAGTGAA GGCTTGACTA AACTTCCATT TACTATCCCA 240

GAGCTGGTGC AGGCATCTCC CTGTCGCAGT TCTGATGGAA TCCTTTATAT GGGTAAAAAG 300

CAGGATATTT GGTACGTGGT TGACATGACT GGGGAGAAAC AGCAGACCTT GACTTCCTTT 360

TTTGCAGAAA GTCTCTGCCC ATCAACATCC CTCCTGTATC TTGGGAGAAC AGAGTACACG 420

ATCACAATGT ATGACACCAA AAAGAAGGAG CTGCGATGGA ATGCCACCTA TTTTGATTAT 480

GCAGCTACTT TGCCTGATGA AGACATAAAA TACAAAATGT CCCACTTTGT GTCCAACGGG 540

GACGGGCTGG TGGTGACCGT GGACAGCGAG TCTGGGGACG TGCTGTGGAT CCAGAATTAC 600

GCGTCCCCCG TGGTGGCCTT TTACATCTGG CAGCGAGAGG GGCTGAGGAA AGTCCTGCAC 660

ACCAACGTGG GCATCGAGAC CCTGCGCTAC CTGACCTTCA TGTCAGGGGA GGTTGGACAC 720

ATCACCAAGT GGAAATATCC CTTCCCAAAG GAAACAGAGA CCAAGAGCAA ACTAACCCCA 780

ACCCTGTACG TGGGGAAATA CTCCACGAGT TTGTACGCGT CGCCCTCCAT GGTGCACGAG 840

GGAGTCACTG TCGTGCCCCG TGGCAGCGCC ATTCCCTTGC TGGAGGGTCC AAAAACAGAA 900

GGAGTCACCA TTGAAGACAA CGGCGAGTGC GTGATCACGC CCAGCACTGA TGTCAAGTTT 960

TCGGGCAGGC TGAAGGAAAA GCACAAACTC AACTACTGGA ATGACTGGCT GCTGATAGGG 1020

CACCATGAAA CACCATTATC TGCCCCCACA AAGATCCTGG AGAAATTCCC AAGCAACTTA 1080

CCAAAGAGGC CTGAAAATGT GATTCCAGCT GGCTCTGAGA AAGCCACTAT TGAAGAGGTC 1140

ATTGACATTG TTGAAGGTTC CTCAACAGAA GGGCCTCCAG CTGCTCCAAA GGATATCGAG 1200

GAGACTCCTG CTCGGCCCAT CCCACGGCCA GAGGCTCCAG TGGACTCCAT GCTGAAGGAC 1260

ATGGCCACGA TCATCCTCAG CACTTTCCTG CTTGTGGGCT GGGTGGCTTT TATCATCACC 1320

TACCCAATGA GTGTCCACCA GCAGCAGCAG AGGCAGCATC AGCTGGAAGA GAAGATCCAG 1380

CTCCTGCAGC AACAGAAGCT GCCCTTCGGT GCTGCCGGTG ACCTCCCGCC CGAGGCAGAT 1440

TTCCTGGACA CGTCGTGTGG CCGGACGGAG AGCTCAGCTG CCAGCACCCC AAACCTGTCC 1500

CCCCGCGCAT CAAACCACTC TGCCTATTCC AACATCTCCA CATCTGATGT CGGGAGCTGC 1560

CTCTCCACTG AGCAAGAAGA GGGAGATGAA GAAGCAAATC GAGTGATTGT TGGCAAGATT 1620

TCGTTTAACC CTAAAGATGT ACTGGGACAT GGTGCTGAAG GGACAATTGT TTACAGGGGC 1680

TCCTTTGATA ACCGTGATGT GGCAGTGAAG AGGATTCTTC CCGAGTGCTT CAGCTTCGCA 1740

GACCGGGAGG TGCAGCTGCT GCGCGAGTCC GATGAGCACC CGAACGTGAT CCGCTACTTC 1800

TGCACGGAGA GGGACCGGCA GTTCCAGTAC ATCGCCATCG AGCTGTGCGC TGCCACCCTG 1860

CAGGAGTACG TTGAGCAGAA GGCCTTCAGC CACCATGGCT TACAACCCAT CACTCTCCTG 1920

CAGCAGACAA CCTCTGGGCT AGCTTACCTG CACTCCCTGA ATATTGTCCA CAGGGACCTG 1980

AAGCCCCACA ACATCCTCAT CTCGATGCCC AACGCTCACG GGAAAGTCAA GGCCATGATT 2040

TCAGACTTTG GGCTGTGTAA GAAGCTGGCG GTGGGCAGGC ACAGCTTCAG CCGCCGCTCG 2100

GGCGTGCCAG GCACTGAAGG CTGGATCGCC CCAGAGATGC TGAGTGAAGA CTGCAAAGAG 2160

AACCCTACAT ACACTGTGGA CATCTTTTCA GCTGGCTGTG TCTTCTATTA CGTGGTGTCT 2220

GAAGGTGGCC ATCCCTTTGG CAAGTCCCTG CAGCGGCAAG CCAACATCCT GCTGGGAGCA 2280

TACAGCCTGG AGGCTCTGGA TGCAGGGAGG CACGAAGACA TTGTTGCTCG TGATTTAATA 2340

GAGCAGATGA TAAACATGGA CCCTCAGAAA CGGCCATCTG CCAGTTGTGT GCTCAAGCAC 2400

CCCTTCTTTT GGAGTCTAGA AAAACAGCTA CAGTTCTTTC AGGATGTTAG TGACCGGATA 2460

GAGAAAGAAT CTTTAGACGG TCCAATAGTC AAGCAGTTAG AAAGAGGTGG AAGAGAAGTG 2520

GTGAAAATGG ACTGGAGAGA GCACATCACT GTTCCTCTTC AGACAGATCT TCGAAAATTC 2580

AGATCCTATA AAGGTGGCTC TGTCCGGGAC CTTCTGAGGG CGATGAGAAA TAAGAAGCAC 2640

CATTACAGGG AACTGCCTCC TGAAGTGCAG GAAACCCTGG GCTCCATCCC AGATGATTTT 2700

GTGTGTTACT TCACAGCTCG TTTCCCTCGC CTGCTCCTGC ACACCTACCA CGCTATGCAC 2760

ATCTGCTGCC AAGAAAGACT CTTCCAGCAT TACTATGCTG AGGACTCTGC AGAGCTGAGC 2820

CTAACAGGAG ACACGGTT 2838

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+GaeGt+v+rGsf++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 542   FNPKDVLGHGAEGTIVYRGSFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  601

         799*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+drqf+yia+elcaa+lq+yve+k ++ +++l+pi+ll+q++sGla+lhsl+ivhrdl

Q: 602   TERDRQFQYIAIELCAATLQEYVEQKAFS-HHGLQPITLLQQTTSGLAYLHSLNIVHRDL  660

         *****************************.99****************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nilis+p+a+gk++++isdfGlckkl+vG++sfsrrsgv+GteGwiape+l+e++ke

Q: 661   KPHNILISMPNAHGKVKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKE  720

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t++vdifs+Gcvfyyv+s+G hpfG+sl+rqanil g++sl+ l   ++e+++a+dli

Q: 721   NPTYTVDIFSAGCVFYYVVSEGGHPFGKSLQRQANILLGAYSLEALDAGRHEDIVARDLI  780

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++mi++dp+krpsa++vlkhp+f

Q: 781   EQMINMDPQKRPSASCVLKHPFF  803

         **********************9

Domain Sequence
(FASTA)

FNPKDVLGHG AEGTIVYRGS FDNRDVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TERDRQFQYI AIELCAATLQ EYVEQKAFSH HGLQPITLLQ QTTSGLAYLH SLNIVHRDLK 120

PHNILISMPN AHGKVKAMIS DFGLCKKLAV GRHSFSRRSG VPGTEGWIAP EMLSEDCKEN 180

PTYTVDIFSA GCVFYYVVSE GGHPFGKSLQ RQANILLGAY SLEALDAGRH EDIVARDLIE 240

QMINMDPQKR PSASCVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013