EKS-TAG-00259

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00259

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	352.5	1.0E-105	26	283	258

Status

Unreviewed

Ensembl Protein

ENSTGUP00000006072

UniProt Accession

H0Z674;

Protein Name

Protein Synonyms/Alias

Gene Name

SIK1

Gene Synonyms/Alias

SIK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000005884	ENSTGUP00000006072	ENSTGUT00000006131

Organism

Taeniopygia guttata

Functional Description

Protein Length

805

Protein Sequence
(FASTA)

MVIMSEFASA PAAAHGQQRP LRVGFYDIER TLGKGNFAVV KLARHRVTKT QVAIKIIDKT 60

RLDPSNLEKI YREVQIMKLL NHPHIIKLYQ VMETKDMLYI VTEFAKNGEM FDHLTSNGHL 120

SESEARKKFW QILSAVEYCH SHHIVHRDLK TENLLLDANM NIKLADFGFG NFYKSGEPLS 180

TWCGSPPYAA PEVFEGKEYE GPHLDIWSLG VVLYVLVCGS LPFDGPNLPT LRQRVLEGRF 240

RIPYFMSEVC LCHPNCETLI RRMLVVDPTK RITISQIKQH KWMQADPSLQ QQQSLCFSMQ 300

NYNSNLGDYN EQVLGIMQTL GIDRQRTVES LQNSSYNHFA AIYYLLLERL KEYWSSQVST 360

RPAAGRQPRP RSSEIANAEM PQDSLTSETL RSSLLYQQPQ SLIQPSLQAE MDCDISNPLQ 420

PVFFPVDTNF NGLFRNRSIS PNSLLETTIS EEVRQEKELE DEIKAFDHPI CIPSNTSRRH 480

TLAEVTTHFY QHVPPCIVIS SSASPTEGTS SDSCLTSSSN DSSVALSSCL AGQVMTGSPA 540

TARMTSPFLA SQSDAPVLQA QGCMGGASLL PVSFQEGRRA SDTSLTQGLK AFRQQLRKNA 600

RAKGFLGLNK IKGFARQVCQ SSSSRAARSA MSPFQHTQPN TCMYSSSGSS REGRSLLEEV 660

LQQQRMLQFQ HHQLLQTACP HSHTPAASSF PSSDGPGTCK ASNSILLSEL QRENSFELAF 720

AGSSQLLQPH FFGVSVSPVS SAAHLLDTQL YISGGGGVPP LAASFSQQQS FSTPSPSYDG 780

VTLQHGDCEM EDLTSSQLGK FVLVK 805

Nucleotide Sequence
(FASTA)

ATGGTGATCA TGTCGGAGTT CGCCTCGGCG CCCGCGGCCG CGCACGGCCA GCAGCGGCCC 60

CTGCGAGTCG GCTTCTACGA CATCGAGAGG ACCCTGGGGA AAGGCAACTT CGCCGTGGTC 120

AAGCTGGCCC GGCACAGGGT GACCAAGACG CAGGTTGCAA TAAAAATAAT AGATAAAACA 180

AGGTTAGACC CAAGCAACCT GGAGAAGATT TATAGAGAAG TTCAGATAAT GAAGCTTTTG 240

AATCATCCCC ACATTATCAA GCTATATCAG GTTATGGAGA CAAAGGATAT GCTGTACATT 300

GTTACTGAGT TTGCAAAGAA TGGAGAAATG TTTGATCACC TGACCTCCAA CGGGCACTTG 360

AGCGAGAGCG AAGCACGGAA GAAGTTCTGG CAGATTCTCT CAGCAGTGGA ATATTGTCAC 420

AGCCACCACA TCGTGCACAG GGATCTCAAA ACAGAGAACC TCCTGCTGGA TGCTAACATG 480

AATATCAAAT TAGCAGACTT TGGCTTTGGA AACTTCTACA AGTCGGGAGA GCCCCTCTCC 540

ACTTGGTGTG GAAGCCCACC CTATGCAGCT CCAGAAGTTT TTGAAGGCAA AGAATATGAA 600

GGCCCTCACC TTGATATATG GAGCCTTGGG GTGGTTCTGT ACGTCCTTGT CTGCGGTTCT 660

CTGCCTTTTG ATGGACCCAA TTTACCAACT CTGAGGCAAA GAGTGCTGGA GGGGCGGTTC 720

CGCATCCCAT ACTTCATGTC CGAAGTTTGT CTTTGTCACC CAAACTGTGA AACACTAATC 780

CGACGGATGC TGGTTGTGGA CCCAACCAAG CGGATAACCA TCTCCCAGAT AAAGCAGCAC 840

AAGTGGATGC AGGCTGACCC CTCCCTTCAG CAGCAGCAGT CCTTGTGCTT CTCCATGCAA 900

AACTACAACT CCAACCTGGG CGACTACAAC GAGCAGGTCC TTGGCATCAT GCAGACCCTT 960

GGCATCGACA GGCAGAGGAC TGTAGAGTCT CTGCAGAACA GCAGCTACAA CCATTTTGCT 1020

GCCATTTATT ACCTGCTCCT GGAGCGCCTC AAGGAGTACT GGAGCAGCCA GGTGTCCACT 1080

CGGCCGGCAG CCGGCCGGCA GCCGCGGCCC AGGAGCTCCG AGATCGCCAA CGCCGAGATG 1140

CCTCAGGACA GTCTCACTAG TGAAACCCTG CGATCATCTC TGCTTTACCA GCAACCTCAG 1200

AGCCTGATTC AGCCATCTTT GCAGGCAGAA ATGGACTGTG ACATAAGCAA TCCATTACAG 1260

CCTGTGTTCT TCCCTGTGGA TACCAACTTC AATGGGCTCT TCCGGAACCG CTCCATCTCC 1320

CCGAACAGCC TGCTGGAGAC CACCATCAGT GAGGAAGTGA GGCAAGAGAA GGAGCTGGAA 1380

GATGAAATTA AGGCATTTGA CCACCCCATC TGCATCCCGA GCAACACCAG CAGGAGGCAC 1440

ACCCTGGCTG AAGTGACCAC CCATTTCTAT CAGCATGTCC CTCCATGTAT AGTCATTTCC 1500

TCCTCTGCCA GCCCCACAGA GGGAACTAGC TCAGACAGCT GCCTTACTTC ATCTTCAAAT 1560

GACAGCTCAG TGGCCCTGAG CAGCTGTTTG GCAGGTCAAG TAATGACGGG GAGCCCGGCC 1620

ACAGCGAGGA TGACGTCGCC TTTCCTCGCT TCCCAGTCTG ACGCTCCCGT CTTACAAGCC 1680

CAGGGCTGCA TGGGAGGTGC TTCTCTCCTG CCTGTCAGCT TCCAAGAAGG AAGGAGAGCA 1740

TCTGATACCT CATTAACTCA AGGCTTGAAG GCTTTTAGGC AGCAGCTGCG GAAGAACGCT 1800

CGAGCCAAGG GGTTCCTCGG CTTGAATAAA ATCAAAGGCT TTGCTCGGCA GGTGTGTCAG 1860

TCCTCCTCCT CTCGGGCAGC AAGGAGTGCC ATGAGCCCTT TCCAGCACAC TCAGCCCAAC 1920

ACCTGCATGT ACAGCAGCAG CGGGAGCAGC AGAGAGGGGA GAAGCCTCCT GGAGGAGGTG 1980

CTGCAGCAGC AGAGAATGCT CCAGTTCCAG CATCACCAAC TGCTCCAAAC AGCTTGTCCC 2040

CACTCCCACA CACCTGCAGC AAGCAGCTTC CCCTCTTCTG ACGGGCCAGG TACCTGCAAA 2100

GCCTCCAACT CCATCCTGCT GTCAGAGCTG CAAAGAGAGA ACTCCTTTGA GCTGGCCTTC 2160

GCTGGCAGCA GCCAACTGCT CCAACCTCAC TTCTTCGGGG TGAGCGTGTC CCCGGTGTCG 2220

TCGGCCGCTC ACCTGCTGGA CACGCAGCTG TACATCAGCG GTGGTGGCGG TGTGCCCCCG 2280

CTGGCCGCCA GCTTCTCCCA GCAGCAGAGC TTCTCCACGC CCTCACCCAG CTACGACGGC 2340

GTCACCCTGC AGCACGGGGA CTGCGAGATG GAGGACCTGA CTTCCAGCCA GCTGGGCAAG 2400

TTCGTGCTGG TCAAGTGA 2418

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y++ +tlG+g+f+ Vkla+h+ tk++va+Kii+k++l+ ++leki+rE++i+k l+hp+i

Q: 26    YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHI  85

         899*********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         ikl++v+etk++ly+v+e+a++ge+fd+++++g+l+e+eark f q++sav+Y+hs++iv

Q: 86    IKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIV  145

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld+++nik+aDFG++n++k+g+ l+t+cGsppYaaPe+++gk+Yegp++D

Q: 146   HRDLKTENLLLDANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLD  205

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkk......lskelesLlrklLv  234

         +WslGvvLy+lv+g+lPfd++nl +l++++l+g+++ip+       +++++e+L+r++Lv

Q: 206   IWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFmsevclCHPNCETLIRRMLV  265

         **************************************9955555556789*********

S: 235   vdpekRatieeilkhewl  252

         vdp+kR+ti++i++h+w+

Q: 266   VDPTKRITISQIKQHKWM  283

         *****************8

Domain Sequence
(FASTA)

YDIERTLGKG NFAVVKLARH RVTKTQVAIK IIDKTRLDPS NLEKIYREVQ IMKLLNHPHI 60

IKLYQVMETK DMLYIVTEFA KNGEMFDHLT SNGHLSESEA RKKFWQILSA VEYCHSHHIV 120

HRDLKTENLL LDANMNIKLA DFGFGNFYKS GEPLSTWCGS PPYAAPEVFE GKEYEGPHLD 180

IWSLGVVLYV LVCGSLPFDG PNLPTLRQRV LEGRFRIPYF MSEVCLCHPN CETLIRRMLV 240

VDPTKRITIS QIKQHKWM 258

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013