EKS-TAG-00327

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00327

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	350.9	3.8E-105	22	272	251

Status

Unreviewed

Ensembl Protein

ENSTGUP00000006292

UniProt Accession

H0Z6U3;

Protein Name

Protein Synonyms/Alias

Gene Name

STK25

Gene Synonyms/Alias

STK25;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000006107	ENSTGUP00000006292	ENSTGUT00000006355

Organism

Taeniopygia guttata

Functional Description

Protein Length

428

Protein Sequence
(FASTA)

AGMAHLREFA SQHSRVDPEE LFTKLERIGK GSFGEVYKGI DNRTKEVVAI KIIDLEEAED 60

EIEDIQQEIT VLSQCDSPYI TRYYGSYLKG TKLWIIMEYL GGGSALDLLK PGPLEETYIA 120

TILREILKGL DYLHSERKIH RDIKAANVLL SEQGDVKLAD FGVAGQLTDT QIKRNTFVGT 180

PFWMAPEVIK QSAYDFKADI WSLGITAIEL AKGEPPNSDL HPMRVLFLIP KNNPPTLEGH 240

HSKPFKEFVE ACLNKDPRFR PTAKELLKHK FITRYTKKTS FLMELIDRFK RWKSEGHGED 300

SSSGDSDIVG DAKDGDQGPI WTFPPTILPN SLSKLLKGMA LHGSQKPTEP IKRQPRSQCL 360

STLVHPVFGE LKDKHKQTGG NVGAMEELEN AFSLAEESCP GISDKLIAHM VERVQRFSHS 420

RNHLTSAR 428

Nucleotide Sequence
(FASTA)

GCAGGCATGG CTCACCTAAG AGAATTTGCT AGCCAGCACT CCAGGGTGGA TCCTGAAGAG 60

CTGTTCACCA AGCTGGAGCG GATCGGCAAG GGATCCTTTG GTGAAGTGTA CAAAGGGATC 120

GACAACCGCA CCAAGGAAGT GGTTGCTATC AAGATCATTG ATCTGGAGGA GGCTGAGGAT 180

GAGATCGAGG ACATTCAGCA GGAGATCACA GTGCTCAGCC AGTGTGACAG CCCCTACATC 240

ACCCGGTACT ATGGCTCCTA CTTGAAGGGC ACTAAGCTGT GGATAATCAT GGAGTACCTG 300

GGAGGAGGTT CAGCCCTGGA TTTGCTGAAG CCAGGACCAC TGGAGGAGAC TTATATAGCT 360

ACTATCCTGA GAGAAATCCT AAAAGGTTTG GATTATTTAC ATTCAGAGAG GAAGATCCAC 420

AGAGACATCA AAGCTGCCAA TGTGCTGCTC TCGGAACAAG GAGATGTGAA ACTGGCTGAC 480

TTTGGGGTGG CTGGACAGCT GACAGACACC CAAATCAAGA GAAACACCTT TGTGGGGACT 540

CCATTCTGGA TGGCACCAGA GGTCATCAAA CAGTCTGCTT ATGACTTCAA GGCAGACATC 600

TGGTCCCTCG GGATTACAGC CATTGAACTA GCAAAGGGAG AGCCTCCAAA TTCTGACTTG 660

CATCCTATGA GGGTTCTCTT CTTGATCCCC AAAAACAACC CTCCAACACT TGAGGGTCAC 720

CACAGCAAGC CCTTCAAGGA GTTTGTGGAA GCCTGCCTCA ATAAGGATCC TAGATTTAGG 780

CCGACAGCTA AAGAATTGCT GAAGCACAAG TTCATCACAC GCTACACCAA GAAAACCTCA 840

TTCCTAATGG AGCTGATCGA TCGATTCAAA CGCTGGAAGT CTGAGGGCCA CGGAGAAGAT 900

TCCAGTTCTG GTGACTCCGA TATCGTTGGA GATGCAAAGG ATGGAGACCA AGGTCCAATC 960

TGGACATTCC CACCAACCAT TCTCCCCAAT TCCTTGAGCA AGCTGCTCAA AGGAATGGCT 1020

CTTCATGGTT CCCAGAAGCC TACTGAGCCC ATCAAGAGGC AACCACGGTC ACAGTGTCTC 1080

TCCACACTTG TTCACCCAGT TTTTGGGGAG CTCAAAGATA AGCACAAGCA GACTGGAGGC 1140

AACGTGGGAG CCATGGAGGA GCTGGAGAAT GCCTTCAGCT TGGCCGAGGA GTCCTGCCCA 1200

GGCATCTCTG ACAAACTGAT AGCACACATG GTGGAGCGGG TCCAAAGGTT TTCACACAGT 1260

CGGAACCACC TGACCTCTGC CCGC 1284

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         ++ le+igkG++g+vy++ +++t+e+vaik+i+le+  +++e++q+ei+vl+++++p+i+

Q: 22    FTKLERIGKGSFGEVYKGIDNRTKEVVAIKIIDLEEAeDEIEDIQQEITVLSQCDSPYIT  81

         7889*******************************99899********************

S: 60    eylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkv  119

         +y++s+lk ++lw++meyl gGs+ dl+k     +l+E+ ia+ilre+lk+L+ylHs+++

Q: 82    RYYGSYLKGTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSERK  138

         *****************************...****************************

S: 120   iHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYde  179

         iHrdika+n+Ll+e+g+VkL+dfgva ql++t+ kr+t+vgtp+wmAPEvi+  ++ Yd

Q: 139   IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK--QSAYDF  196

         ****************************************************..9*****

S: 180   kaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclq  239

         kaDiwslGItaiela+gepP +dl+p+++l++i+kn+pp+l+ +   sk fkefve+cl+

Q: 197   KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGH--HSKPFKEFVEACLN  254

         *****************************************666..9*************

S: 240   knpekRpsasellkhkFl  257

         k+p++Rp+a+ellkhkF+

Q: 255   KDPRFRPTAKELLKHKFI  272

         *****************7

Domain Sequence
(FASTA)

FTKLERIGKG SFGEVYKGID NRTKEVVAIK IIDLEEAEDE IEDIQQEITV LSQCDSPYIT 60

RYYGSYLKGT KLWIIMEYLG GGSALDLLKP GPLEETYIAT ILREILKGLD YLHSERKIHR 120

DIKAANVLLS EQGDVKLADF GVAGQLTDTQ IKRNTFVGTP FWMAPEVIKQ SAYDFKADIW 180

SLGITAIELA KGEPPNSDLH PMRVLFLIPK NNPPTLEGHH SKPFKEFVEA CLNKDPRFRP 240

TAKELLKHKF I 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0007163	; P:establishment or maintenance of cell polarity
GO:0051645	; P:Golgi localization

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013