EKS-TAG-00172

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00172

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/CDC7	518.6	4.9E-156	21	526	506

Status

Unreviewed

Ensembl Protein

ENSTGUP00000006330

UniProt Accession

H0Z6Y1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDC7

Gene Synonyms/Alias

CDC7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000006148	ENSTGUP00000006330	ENSTGUT00000006394

Organism

Taeniopygia guttata

Functional Description

Protein Length

531

Protein Sequence
(FASTA)

AGVKKDIEKL YEAVPQLVNV FKIKEKIGEG TFSSVYLATA QLQTGYEEKI ALKHLIPTSH 60

PLRIAAELQC LTVAGGQDNV MGVKYCFRKN DHVVIVMPYL EHESFLDILS SLSFEEVREY 120

MFNLFKALRR IHHFGIVHRD VKPSNFLYNR QLKKYALVDF GLAQGTPDTK IELLKTAHSE 180

DQQGSCLQTN PIVTSGNGVS VSVTAPKQIA QQTASKAADR RSSSLSKVQM KQGRGGKEDS 240

VHHSVQRSVF GERNFNVYSS TYQENSSTKL IKQPKMIDVS SRKLVTKKKI ISTKTVSNGA 300

ARKAASGCPL NVHCDCYATD RVCSVCLSRR QQVAPRAGTP GFRAPEVLTK CPTQTTAIDM 360

WSAGIIFLSL LSGRYPFFKA SDDLTALAQI MTVRGSRETI QAARTFGKSV VCTQVVPAQN 420

LRTLCEKLRG TNSSCKRSQG EGPGRSDNNT ALSVAADKPC APETLGKQIQ HLQNVQESDG 480

ALDIKAADMK GWDQVPDEAY DLLDKLLDLN PATRITAKEA LLHPFFKDIR L 531

Nucleotide Sequence
(FASTA)

GCAGGAGTAA AAAAAGATAT TGAAAAACTT TATGAAGCAG TGCCACAGCT TGTAAATGTG 60

TTTAAAATAA AGGAAAAAAT TGGGGAAGGT ACTTTTAGCT CTGTGTACTT GGCCACAGCA 120

CAGCTGCAAA CAGGATATGA GGAAAAAATT GCTCTGAAGC ACTTGATTCC AACCAGCCAC 180

CCTCTGCGAA TAGCTGCTGA ACTTCAGTGC CTCACAGTGG CAGGGGGACA AGATAATGTT 240

ATGGGAGTTA AATACTGCTT TAGGAAAAAT GATCACGTTG TTATTGTTAT GCCGTATCTG 300

GAGCATGAAT CCTTCTTGGA CATTTTGAGT TCCCTTTCCT TTGAAGAAGT GAGGGAATAC 360

ATGTTTAATC TGTTTAAAGC GTTGAGGCGC ATTCATCACT TCGGTATTGT TCACCGTGAC 420

GTCAAGCCCA GCAACTTCCT CTACAACAGG CAGCTAAAAA AGTATGCCTT GGTAGATTTT 480

GGCTTGGCAC AAGGAACCCC TGATACGAAA ATTGAGCTTC TTAAAACTGC CCACTCTGAA 540

GACCAGCAGG GAAGTTGCTT GCAAACTAAT CCCATTGTAA CCTCGGGAAA TGGGGTTTCT 600

GTCAGTGTCA CAGCACCTAA ACAGATAGCT CAACAGACAG CCTCAAAAGC AGCTGATAGA 660

AGGTCCAGCT CGCTTTCAAA AGTACAGATG AAACAAGGAA GAGGAGGAAA GGAGGACTCT 720

GTGCACCATT CTGTGCAGCG CTCTGTCTTT GGAGAGAGGA ATTTCAATGT CTATAGCTCC 780

ACATACCAGG AGAATTCAAG CACAAAACTC ATAAAGCAAC CAAAGATGAT AGATGTTTCA 840

TCTAGGAAGT TAGTAACAAA GAAGAAGATT ATTTCTACCA AAACTGTGAG CAATGGGGCA 900

GCCAGGAAAG CTGCCAGTGG TTGCCCTTTA AACGTGCACT GTGACTGTTA TGCAACGGAC 960

AGAGTTTGCA GTGTTTGCCT TTCAAGGCGT CAGCAAGTGG CTCCCAGGGC AGGAACACCT 1020

GGATTCAGAG CACCAGAAGT ATTAACAAAG TGCCCCACTC AGACCACAGC AATAGACATG 1080

TGGTCTGCAG GAATCATATT CCTTTCTCTG CTCAGTGGAC GGTATCCATT TTTCAAAGCA 1140

AGTGATGATT TAACTGCTCT GGCACAAATT ATGACAGTTC GTGGATCCAG AGAAACCATT 1200

CAGGCTGCTA GAACTTTTGG AAAATCAGTT GTGTGTACCC AAGTTGTCCC AGCTCAAAAC 1260

CTACGAACCC TCTGTGAAAA GCTGAGAGGA ACAAATAGCA GCTGTAAGAG ATCTCAGGGG 1320

GAAGGGCCCG GCAGGTCTGA CAACAACACA GCTTTGTCAG TTGCAGCAGA CAAACCTTGT 1380

GCTCCTGAGA CACTTGGAAA ACAAATTCAA CACTTACAGA ATGTTCAGGA AAGTGACGGT 1440

GCTTTGGATA TCAAGGCAGC TGACATGAAA GGATGGGATC AGGTTCCTGA TGAAGCATAT 1500

GACCTACTTG ATAAGCTACT AGACTTAAAC CCTGCAACAA GAATAACTGC AAAAGAGGCT 1560

TTGCTGCATC CTTTTTTTAA AGACATAAGG CTCTGA 1596

Domain Profile

S: 1     fkikdkiGeGtfssvylataqleegleekialkhliptshPeriaaeLelltvlgGqenv  60

         fkik+kiGeGtfssvylataql++g+eekialkhliptshP riaaeL++ltv+gGq+nv

Q: 21    FKIKEKIGEGTFSSVYLATAQLQTGYEEKIALKHLIPTSHPLRIAAELQCLTVAGGQDNV  80

         9***********************************************************

S: 61    vglkecfrkndsvvivlpylehesfldllrslsfqevreYlrnLlvalkrvhkfgivhrD  120

         +g+k+cfrknd+vviv+pylehesfld+l slsf+evreY++nL++al+r+h+fgivhrD

Q: 81    MGVKYCFRKNDHVVIVMPYLEHESFLDILSSLSFEEVREYMFNLFKALRRIHHFGIVHRD  140

         ************************************************************

S: 121   vkpsnfLynrrlkkfaLvDfGLaq..............seaqkeecsrn..........l  156

         vkpsnfLynr+lkk+aLvDfGLaq              se q+ +c ++

Q: 141   VKPSNFLYNRQLKKYALVDFGLAQgtpdtkiellktahSEDQQGSCLQTnpivtsgngvS  200

         **************************************9*******99889999999885

S: 157   lsaavekevd..................................................  166

         +s +++k++

Q: 201   VSVTAPKQIAqqtaskaadrrssslskvqmkqgrggkedsvhhsvqrsvfgernfnvyss  260

         55555555556777788889999*************************************

S: 167   ....................................................tcdcygtd  174

                                                              cdcy+td

Q: 261   tyqensstklikqpkmidvssrklvtkkkiistktvsngaarkaasgcplnvHCDCYATD  320

         ************************************************************

S: 175   kvcsvclsrrqqvanraGtpGfraPevLlkipdqttaiDiwsaGvilLsllsgryPffka  234

         +vcsvclsrrqqva+raGtpGfraPevL+k+p+qttaiD+wsaG+i+LsllsgryPffka

Q: 321   RVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPTQTTAIDMWSAGIIFLSLLSGRYPFFKA  380

         ************************************************************

S: 235   sddlealaeivtilGsreiikaakafgksvllskevp.......................  271

         sddl+ala+i+t++Gsre+i+aa++fgksv++++ vp

Q: 381   SDDLTALAQIMTVRGSRETIQAARTFGKSVVCTQVVPaqnlrtlceklrgtnssckrsqg  440

         ***************************************************999999999

S: 272   ..............................................dsdsye.......P  278

Q: 441   egpgrsdnntalsvaadkpcapetlgkqiqhlqnvqesdgaldikaA----DmkgwdqvP  496

         99999999999999999999999988888888888766666655541....05555677*

S: 279   deaydlldkllelnPakritaeealkhpff  308

         deaydlldkll+lnPa rita+eal+hpff

Q: 497   DEAYDLLDKLLDLNPATRITAKEALLHPFF  526

         *****************************8

Domain Sequence
(FASTA)

FKIKEKIGEG TFSSVYLATA QLQTGYEEKI ALKHLIPTSH PLRIAAELQC LTVAGGQDNV 60

MGVKYCFRKN DHVVIVMPYL EHESFLDILS SLSFEEVREY MFNLFKALRR IHHFGIVHRD 120

VKPSNFLYNR QLKKYALVDF GLAQGTPDTK IELLKTAHSE DQQGSCLQTN PIVTSGNGVS 180

VSVTAPKQIA QQTASKAADR RSSSLSKVQM KQGRGGKEDS VHHSVQRSVF GERNFNVYSS 240

TYQENSSTKL IKQPKMIDVS SRKLVTKKKI ISTKTVSNGA ARKAASGCPL NVHCDCYATD 300

RVCSVCLSRR QQVAPRAGTP GFRAPEVLTK CPTQTTAIDM WSAGIIFLSL LSGRYPFFKA 360

SDDLTALAQI MTVRGSRETI QAARTFGKSV VCTQVVPAQN LRTLCEKLRG TNSSCKRSQG 420

EGPGRSDNNT ALSVAADKPC APETLGKQIQ HLQNVQESDG ALDIKAADMK GWDQVPDEAY 480

DLLDKLLDLN PATRITAKEA LLHPFF 506

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008284	; P:positive regulation of cell proliferation
GO:0033261	; P:regulation of S phase

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013